Şehribanu Işık

ORCID: 0000-0003-2999-059X
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About
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Research Areas
  • Neonatal Respiratory Health Research
  • Infant Development and Preterm Care
  • Neonatal and fetal brain pathology
  • Cardiovascular Issues in Pregnancy
  • Congenital Heart Disease Studies
  • Pituitary Gland Disorders and Treatments
  • Streptococcal Infections and Treatments
  • Neonatal and Maternal Infections
  • Respiratory Support and Mechanisms
  • Apelin-related biomedical research
  • Nitric Oxide and Endothelin Effects
  • Pediatric Pain Management Techniques
  • Parathyroid Disorders and Treatments
  • Vasculitis and related conditions
  • Growth Hormone and Insulin-like Growth Factors
  • Tracheal and airway disorders
  • Thyroid Cancer Diagnosis and Treatment
  • Congenital Diaphragmatic Hernia Studies
  • Thermal Regulation in Medicine
  • Adrenal and Paraganglionic Tumors
  • Infectious Encephalopathies and Encephalitis
  • Intestinal Malrotation and Obstruction Disorders
  • Congenital Ear and Nasal Anomalies
  • Inflammasome and immune disorders
  • Psoriasis: Treatment and Pathogenesis

State Hospital
2025

Karadeniz Technical University
2024-2025

Sağlık Bilimleri Üniversitesi
2019-2024

Ankara Bilkent City Hospital
2023-2024

Bilkent University
2024

Çankaya University
2020-2023

University of Health Sciences
2022

Memorial Ankara Hospital
2022

University of Health Sciences Antigua
2022

Ankara Mevki Asker Hastanesi
2020-2021

ABSTRACT Doxorubicin (DOX) is an anthracycline antibiotic widely used as antineoplastic agent. L‐theanine (LTN) a unique amino acid obtained from tea ( Camellia sinensis ) and highly valuable nutraceutical additive in the food industry. The aim of this study was to investigate effects LTN on ovarian endoplasmic reticulum stress (ERS) DOX‐induced rats. rats were divided into one four groups: Control (saline), DOX (20 mg/kg DOX, i.p.), + LTN200 (DOX 200 LTN) LTN400 400 LTN). administered first...

10.1002/fsn3.70150 article EN cc-by Food Science & Nutrition 2025-04-01

Amaç: Doğumsal kalp hastalıkları (DKH) yenidoğanlarda yaygın görülen sağlık sorunları arasındadır. prenatal ve postnatal dönemlerde çeşitli yöntemler ile teşhis edilirken, işitme kayıpları, doğum sonrası yapılan taramalarla tespit edilebilir. hastalıklarında kalbin yapısı bozulduğu için akciğerlere vücudun diğer organlarına yeterli oksijen sağlanamaz. Yenidoğan taraması (YDİT) açısından DKH risk faktörü olarak tanımlanmamış olsa da yetersizliğine duyarlı birçok organ gibi korti organı...

10.51536/tusbad.1614470 article TR Türkiye Sağlık Bilimleri ve Araştırmaları Dergisi 2025-04-28

Leukotrienes, free oxygen radicals, tumor necrosis factor-alpha, and inflammatory mediators play major roles in the development of necrotizing enterocolitis (NEC). Rhus coriaria (RC: sumac) extracts may enhance cell viability by reinforcing defenses against radical species several progressive diseases as well diseases. The aim present study was to evaluate effects RC a rat NEC model terms intestinal damage. Newborn pups were separated into three groups: control, NEC, treated with RC....

10.1111/jfbc.13068 article EN Journal of Food Biochemistry 2019-10-03

The EDIN scale (Échelle Douleur Inconfort Nouveau-Né, neonatal pain and discomfort scale) heart rate variability has been used for the evaluation of prolonged pain. aim our study was to assess value newborn infant parasympathetic (NIPE) index in preterm infants with chest tube placement due pneumothorax.This prospective observational assessed a gestational age between 33 35 weeks undergoing installation tubes. Prolonged using NIPE index.There significant correlation (r=-0.590, P=0.003). is...

10.3345/kjp.2017.05939 article EN cc-by-nc-nd Korean Journal of Pediatrics 2018-09-16

Background: Infants fed breast milk are known to have lower rates of childhood obesity. However, there is evidence suggesting an increased risk obesity in infants who receive from a diabetic mother. The aim this study was investigate the calorie and macronutrient content colostrum mothers with gestational diabetes mellitus (GDM). Methods: This prospective, controlled included had diagnosis GDM control group without delivered at term. Colostrum samples were analyzed for macronutrients (fat,...

10.1089/bfm.2021.0209 article EN Breastfeeding Medicine 2022-02-10

Abstract BACKGROUND Pulse oximetry is commonly used to monitor arterial oxygen saturation and heart rate during the transition period reference intervals have been determined. However, effect of change in on tissue oxygenation does not seem be same. So, a non-invasive method for monitoring cerebral or regional will potentially useful vulnerable infants. This study aims evaluate effectiveness autoregulation first 10 min after delivery term late preterm newborns without resuscitation...

10.1093/tropej/fmae004 article EN Journal of Tropical Pediatrics 2024-02-07

Psoriasis is a common chronic inflammatory skin disease caused by genetic and epigenetic factors. There are conflicting results in the literature about association between psoriasis methylenetetrahydrofolate reductase gene (MTHFR), ranging from strong linkage to no association. To investigate germline MTHFR polymorphisms C677T A1298C with risk Turkish population. The study enrolled 84 patients 212 healthy controls (HCs) without any history of psoriasis. DNA was extracted peripheral blood...

10.1111/ced.12909 article EN Clinical and Experimental Dermatology 2016-12-27

Patent ductus arteriosus (PDA) has been associated with early morbidities and long-term developmental problems in very preterm infants.The aim of this study is to investigate the effect patent medical treatment on outcomes low birth weight infants.This a retrospective case control observational study.The included infants who were born before 30 weeks' gestation less than 1,500 g underwent neurodevelopmental testing at corrected age 24 months during follow-up our centre. The results...

10.1111/cch.12997 article EN Child Care Health and Development 2022-03-11

Objective Sepsis is one of the most significant contributors to mortality and morbidity in neonatal population. The need find specific biomarkers that provide meaningful information about diagnosis sepsis still ongoing. This study aimed investigate utility N-terminal pro-brain natriuretic peptide (NT-proBNP) as a diagnostic biomarker newborn infants with late-onset sepsis. Methods A prospective, observational was conducted intensive care unit between July 2016 January 2017. patients...

10.1055/s-0039-1692341 article EN Journal of Pediatric Infectious Diseases 2019-05-22

<h3>Background:</h3> Understanding disease progression in patients with Takayasu arteritis (TA) has not always been simple for rheumatologists due to possibility of mild vascular inflammation without clinical signs and ongoing fibrosis independent activity. There is no hesitation regarding the indication radiological imaging case differences or laboratory findings however there consensus among on whether should be performed at regular intervals detect <h3>Objectives:</h3> It was aimed...

10.1136/annrheumdis-2024-eular.5892 article EN Annals of the Rheumatic Diseases 2024-06-01

<h3>Background:</h3> A significant portion of Takayasu arteritis (TA) patients have cardiac valvular involvement, and it is reported that the affected valve usually aortic [1, 2]. Cardiac involvement often leads to insufficiency progressive deterioration in functions negatively affects disease outcomes. Involvement ascending aorta known as a risk factor for (AV) insufficiency. However, more data on factors prognosis are needed. <h3>Objectives:</h3> The aim this study determine frequency AV...

10.1136/annrheumdis-2024-eular.5914 article EN Annals of the Rheumatic Diseases 2024-06-01

Purpose: The aim of our present study was to investigate the simultaneous findings both blood and cerebrospinal fluid cultures determine etiological pathogens responsible for neonatal sepsis meningitis in intensive care unit.Materials Methods: This carried out newborn department from November 2013 October 2015. During this period 732 neonates with signs symptoms were included study. Sepsis work up performed taken eligible patients.Results: Cerebrospinal positive in100 (13.7%) cases. Positive...

10.17826/cumj.485624 article EN Çukurova medical journal (Online)/Çukurova medical journal 2019-09-13

Objective: Asymmetric dimethylarginine (ADMA), a methylated L-arginine analog, is major endogenous competitive inhibitor of Nitric oxide (NO).NO an important critical vasoactive mediator synthesized by the vascular endothelium, previously referred to as endothelium-derived relaxing factor.ADMA novel risk factor and statement endothelial dysfunction.ADMA levels are clinically increased in several clinical conditions such diabetes mellitus (DM), hypertension, insulin resistance syndrome,...

10.12956/tjpd.2016.265 article EN Turkish Journal of Pediatric Disease 2016-12-28
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