A5014957135- Systemic Lupus Erythematosus Research
- Systemic Sclerosis and Related Diseases
- Adolescent and Pediatric Healthcare
- Childhood Cancer Survivors' Quality of Life
- Drug-Induced Ocular Toxicity
- Forensic Anthropology and Bioarchaeology Studies
- Autoimmune and Inflammatory Disorders Research
- Lymphatic System and Diseases
- Dermatologic Treatments and Research
- Child and Adolescent Health
- Rheumatoid Arthritis Research and Therapies
- Cancer Cells and Metastasis
- Spondyloarthritis Studies and Treatments
- Primary Care and Health Outcomes
- Autoimmune Bullous Skin Diseases
- Retinal Diseases and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cancer Treatment and Pharmacology
- Eosinophilic Esophagitis
- Morphological variations and asymmetry
- Paleopathology and ancient diseases
- Inflammatory Myopathies and Dermatomyositis
- Forensic and Genetic Research
- Pediatric health and respiratory diseases
University of Utah
2015-2025
George E. Wahlen Department of VA Medical Center
2018
Mercyhurst University
2009-2012
University of Tennessee Health Science Center
2012
To better define components of successful Health Care Transition (HCT) we surveyed patients in an academic Rheumatology clinic at the University Utah. Results can be used to improve HCT over time. We asked and parents complete Mind Gap Feedback survey as part a larger registry dataset collected from said clinic. were analyzed. Survey responses are presented averages. Sixty-five 42 completed Gap. Patients report that is outperforming their expectations 20 22 variables. Parents underperforming...
To standardly assess and describe nailfold videocapillaroscopy (NVC) assessment in children adolescents with juvenile rheumatic musculoskeletal diseases (jRMD) vs healthy controls (HCs).In consecutive jRMD matched HCs from 13 centres worldwide, 16 NVC images per patient were acquired locally read centrally international consensus standard evaluation of the EULAR Study Group on Microcirculation Rheumatic Diseases. A total 95 patients JIA, 22 JDM, 20 childhood-onset SLE (cSLE), SSc (jSSc), 21...
Studies of skeletal development frequently document populational incidences bilateral asymmetry. Degenerative morphological changes, attributed to age related and irregular ossification, may also progress asymmetrically, either as the result asymmetric biomechanical factors expressed over lifespan, expression physiological processes, or progressive magnification asymmetry acquired previously during development. This study illustrates effects on at death estimates obtained from human remains....
Abstract Background Juvenile idiopathic arthritis (JIA)-associated uveitis is a chronic paediatric ocular inflammatory condition that can result in visual impairment. Adalimumab, tumour necrosis factor (TNF)-alpha inhibitor, effectively controls joint and eye inflammation; however, its long-term use may increase the risk of adverse health outcomes place an undue financial burden on patient healthcare system given high cost. There great interest for patients to stop adalimumab following...
The transition of health care from Pediatric to Adult providers for adolescents and young adults with chronic disease is associated poor outcomes. Despite the importance this transition, over 80% these patients do not receive services necessary care. In 2018, we initiated a clinic structure, integrating an Internal Medicine - Pediatrics trained Rheumatologist in Rheumatology guide transition. Our goal was improve We report methods its preliminary outcomes.For referred clinic, assumed medical...
Abstract Background The concept of mixed connective tissue disease (MCTD) as a unique has endured for half century. Disease onset can be in adulthood or juvenile (jMCTD) and is characterized by overlapping features systemic lupus erythematosus (SLE), polymyositis dermatomyositis (PM/DM) sclerosis (SSc). No universally accepted classification criteria MCTD exists, however agreed upon include the presence high titers U1 small nuclear ribonucleoprotein particle antibodies (U1snRNP) peripheral...
Despite poor health care transition outcomes among young adults with pediatric rheumatic diseases, adoption of best practices is low. We sought to understand how structured processes were operationalized within rheumatology and what factors perceived enable adaptations during a global pandemic.We conducted mixed methods study team leaders' experiences an interim analysis pilot project implement policy discussions at sites in the Childhood Arthritis Rheumatology Research Alliance Transition...
Objective Uptake of evidence‐informed health care transition processes among pediatric rheumatologists is low despite poor outcomes from to adult care. We piloted a learning collaborative model implement guides. dually assessed implementation and changes in reported patient–care team discussions about transition. Methods This was type II hybrid effectiveness‐implementation pilot study guide dissemination patients at least 14 years old with rheumatic conditions across nine rheumatology...
Objective. Early diagnosis of systemic sclerosis (SSc) is imperative, and Raynaud phenomenon (RP) an important component progressive vasculopathy. Nailfold videocapillaroscopy (NVC) a well-established tool that can quantify structural vascular abnormalities. Digital thermal monitoring (DTM) assesses microvascular functional dysfunction related to thermoregulation. In this study, we investigated the correlation NVC patterns DTM variables in patients with SSc. Methods. Patients SSc according...
Our purpose was to determine the frequency of normal diffusing capacity for carbon monoxide defined as ⩾70% predicted, in those diagnosed with pulmonary arterial hypertension Pulmonary Hypertension Assessment and Recognition Outcomes Scleroderma cohort. We compared reduced <70% order better clarify role function testing a screening test understand this population.Entry criteria included right heart catheterization mean artery pressure ⩾25 mm Hg capillary wedge ⩽15 Hg. Demographics,...
Objective Observational research of axial spondyloarthritis (axSpA) is limited by a lack methods for identifying diverse axSpA phenotypes in large datasets. Algorithms were previously designed to identify broad spectrum patients with axSpA, including not identifiable diagnosis codes. The study objective was estimate the performance identification general Veterans Affairs (VA) population. Methods A patient sample known status (n = 300) established chart review. For feasibility, this enriched...
Abstract Background Retinal toxicity is a rare adverse event related to the use of hydroxychloroquine (HCQ). To address this, in 2016, American Academy Ophthalmology (AAO) issued guidelines recommending that HCQ not exceed 5 mg/kg/day. We analyzed prescribing habits at our institution, compared these guidelines, and used surveys determine opinions on guidelines. then introduced, prospective non-controlled study, clinical decision support (CDS) tool into electronic medical record (EMR) study...
e21077 Background: CTCs have prognostic capability in the treatment of MBC based on a dichotomous level ≥5/7.5 ml blood (Hi) vs. <5/7.5 (Lo) at baseline and first follow-up. The value beyond is not well established, implication values that are reduced but remain high has been explored. Methods: Chart review patients (pts) 1 st or 2 nd line MBC, with CTC determinations between 2/2008 9/2011, were retrospectively identified large community oncology practice. Pts ≥2 ≥5 eligible....
p>Background: Fatigue is common in inflammatory arthritis (IA). Obstructive sleep apnea (OSA) causes fatigue and IA. OSA IA are associated with systemic inflammation, including elevated levels of tumor necrosis factor alpha (TNFα). Tumor inhibitors (TNFi) reduce musculoskeletal symptoms The effects TNFi on unknown. Our goal was to explore the relationships between TNFi, fatigue, IA. Methods: Consecutive patients starting for high risk were enrolled. assessed Apnea Hypopnea Index (AHI)...
Abstract Background Retinal toxicity is a rare adverse event related to the use of hydroxychloroquine (HCQ). To address this, in 2016, American Academy Ophthalmology (AAO) issued guidelines recommending that HCQ not exceed 5 mg/kg/day. We analyzed prescribing habits at our institution, compared these guidelines, and used surveys determine opinions on guidelines. then introduced, prospective non-controlled study, an electronic medical record (EMR) tool study how this intervention might affect...