A5113882118- Extracellular vesicles in disease
- MicroRNA in disease regulation
- RNA Interference and Gene Delivery
- Barrier Structure and Function Studies
- Drug Transport and Resistance Mechanisms
- Connexins and lens biology
- Endometriosis Research and Treatment
- Graphene and Nanomaterials Applications
- Immune cells in cancer
- Biomarkers in Disease Mechanisms
- Microbial Natural Products and Biosynthesis
- Family Dynamics and Relationships
- Fecal contamination and water quality
- Chemical Synthesis and Analysis
- Traditional Chinese Medicine Analysis
- Wastewater Treatment and Reuse
- Circular RNAs in diseases
- Plant pathogens and resistance mechanisms
- Education, Achievement, and Giftedness
- Legume Nitrogen Fixing Symbiosis
- Plant Molecular Biology Research
- Nanoplatforms for cancer theranostics
- Reproductive Health and Technologies
- Advancements in Transdermal Drug Delivery
- Advanced Drug Delivery Systems
Anhui University of Traditional Chinese Medicine
2024
Hebei University of Technology
2024
Xinjiang Medical University
2022-2024
Duquesne University
2019-2023
Heilongjiang Bayi Agricultural University
2023
Binzhou University
2023
Binzhou Medical University
2023
National Medical Products Administration
2022
China Pharmaceutical University
2022
Jilin International Studies University
2022
Based on the control-value theory (CVT), this study qualitatively investigated relationship between appraisals, achievement emotions (mainly enjoyment, pride, and hope), English-as-a-foreign-language (EFL) performance, explored other antecedents of in addition to appraisals. Data were collected from six Chinese high school students through two semi-structured interviews one focus group discussion. With thematic analysis, data analyzed under framework CVT using NVivo 11.0. Results indicate...
Infertility is one of the three major public health problems in world, bringing immense physical and psychological damage to men affecting quality men's fertility life. Thus, purpose this study was analyze status social support, stress, mindfulness, life infertile men, explore dual mediating effects support stress on mindfulness quality.A case-control group conducted, with 246 case 149 control group. The Social Support Scale, Fertility Stress Mindfulness Quality Life Scale were used...
The blood-brain barrier BBB consists of endothelial cells that form a between the systemic circulation and brain to prevent exchange non-essential ions toxic substances. Tight junctions (TJ) effectively seal paracellular space in monolayers resulting an intact barrier. This study describes LY-based fluorescence assay can be used determine its apparent permeability coefficient (Papp) turn kinetics formation confluent tight junction integrity hCMEC/D3 monolayers. We further demonstrate...
First Asp-containing actinomycin and two unusual tetracyclic chromophoric analogues with potent cytotoxic antibacterial activities from marine-derived Streptomyces sp. strain S22.
The blood-brain barrier BBB consists of endothelial cells that form a between the systemic circulation and brain to prevent exchange non-essential ions toxic substances. Tight junctions (TJ) effectively seal paracellular space in monolayers resulting an intact barrier. This study describes LY-based fluorescence assay can be used determine its apparent permeability coefficient (Papp) turn kinetics formation confluent tight junction integrity hCMEC/D3 monolayers. We further demonstrate...
This study aims to investigate the effects of Linggui Zhugan Decoction(LGZGD) on myocardial fibrosis(MF) and Lats1/Yap signaling pathway in mice after infarction(MI), exploring its role mechanism inhibiting MF. The MI-induced ischemic mouse model was established by left anterior descending coronary artery ligation, followed continuous intervention for six weeks. Doppler ultrasound imaging-system small animals used detect ventricular ejection fraction(LVEF), fractional shortening(LVFS),...
This study aims to investigate the effect of Linggui Zhugan Decoction(LGZGD) on autophagy in mouse model chronic heart failure(CHF) induced by myocardial infarction(MI), as well regulatory LGZGD hypoxia-inducible factor-1α(HIF-1α)/heme oxygenase-1(HO-1) signaling pathway, based bioinformatics and animal experiments. The active ingredients corresponding targets were retrieved from Traditional Chinese Medicine Systems Pharmacology Analysis Database, GEO, GeneCards, DisGeNET searched for...
The possible targets underlying the activity of bufalin on renal cell carcinoma (RCC) were investigated using network pharmacology and experimental approaches. PharmMapper other databases explored for predicting RCC-related targets. Finally, enriched pathways analyzed by Kyoto Encyclopedia Genes Genomes (KEGG) Gene Ontology (GO) pathway enrichment analyses. Furthermore, in vitro experiments used to verify activation AKT MAPK signaling human mesangial cells. therapeutic related identified via...
Abstract We have demonstrated, for the first time that microvesicles, a sub-type of extracellular vesicles (EVs) derived from hCMEC/D3: human brain endothelial cell (BEC) line transfer polarized mitochondria to recipient BECs in culture and neurons mice acute cortical hippocampal slices. This mitochondrial increased ATP levels by 100 200-fold (relative untreated cells) exposed oxygen-glucose deprivation, an vitro model cerebral ischemia. also demonstrated larger EV fraction, but not exosomes...