A5101682243- Bone health and osteoporosis research
- Rheumatoid Arthritis Research and Therapies
- Bacterial Identification and Susceptibility Testing
- Systemic Lupus Erythematosus Research
- Diphtheria, Corynebacterium, and Tetanus
- Clostridium difficile and Clostridium perfringens research
- Systemic Sclerosis and Related Diseases
- Bone health and treatments
- Autoimmune and Inflammatory Disorders Research
- Spondyloarthritis Studies and Treatments
- Body Composition Measurement Techniques
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Psoriasis: Treatment and Pathogenesis
- Sports injuries and prevention
- Monoclonal and Polyclonal Antibodies Research
- Multiple Sclerosis Research Studies
- Inflammatory Myopathies and Dermatomyositis
- Immunodeficiency and Autoimmune Disorders
- Chronic Lymphocytic Leukemia Research
- Nutrition and Health Studies
- Medical Device Sterilization and Disinfection
- Hip and Femur Fractures
- Occupational Health and Performance
- Bone and Joint Diseases
- Preterm Birth and Chorioamnionitis
Poznan University of Medical Sciences
2014-2025
Medical University of Warsaw
1997-2022
Krakowskie Centrum Rehabilitacji
2013
Medical University of Silesia
2012
Wojskowy Instytut Medyczny
1995
Background The mechanism of cognitive dysfunction in systemic lupus erythematosus (SLE) is still not fully understood. Even though many SLE patients present some neurological dysfunction, including various deficits, neither a specific pattern nor structural changes associated with impairment have been established. Moreover, although prevalent and bothersome, deficits included the most recent diagnostic criteria. Purpose aim this study was to determine relationship between presence white...
Systemic sclerosis (SSc) is a connective tissue disease characterized by progressive fibrosis of the skin and internal organs, leading to their failure disturbances in morphology function blood vessels. The affects people different ways, identifying how difficulties limitations are related quality life may contribute designing helpful interventions. aim this study was identify factors associated with SSc.This cross-sectional conducted 11 rheumatic centres Poland. Patients diagnosed SSc were...
Long-term analyses of demographical and clinical characteristics COVID-19 patients can provide a better overview the course disease. They also help understand whether changes in infection symptomatology, disease severity, outcome occur over time. We aimed to analyze demographics, early symptoms infection, laboratory parameters, manifestation hospitalized during first 17 months pandemic Poland (March 2020–June 2021). The patients’ data (n = 5199) were extracted from national SARSTer database...
Tofacitinib is a newly approved small-molecule targeted synthetic disease-modifying antirheumatic drug. The drug was designed as selective and specific inhibitor of pro-inflammatory receptor signalling. inhibits the process intracellular signalling from to cellular nucleus inflammation via new pathway (inhibition Janus kinases), which unavailable biological medicines. has been for use in treatment patients with moderate severe active RA. may be used combination methotrexate or another...
The purpose of this study was to analyze the influence aqua fitness training in deep water on bone tissue. performed with 18 postmenopausal women separated into two groups: and control groups. Before after program, hip spine areal mineral density were measured along biochemical parameters serum concentration osteocalcin (OC) C-terminal telopeptide type I collagen (CTX). most significant effect found differences between groups terms femur strength index (p < 0.05) during period program....
Ultrasound examinations are recognised as being safe. The greatest epidemiological threat during the performance of examination is transfer pathogenic and opportunistic microorganisms between patients from personnel to patients. Colonization skin with bacteria immunocompromised high risk may lead infection following an ultrasound scan.To identify evaluate strains occurring on equipment subjected unexpected control performed by a local infectious diseases team. We assumed that transducers,...
<h3>Background</h3> SB4 is approved by the European Medicines Agency as a biosimilar of etanercept reference product (ETN). The phase I clinical study results and 52-week III have been reported previously.<sup>1–3</sup> <h3>Objectives</h3> To evaluate long term safety, immunogenicity, efficacy continuing vs. switching (as will occur in practice) from ETN to patients with moderate severe RA. <h3>Methods</h3> randomised, double-blind period consisted 52 weeks treatment either weekly dose...
Corynebacterium coyleae is part of the commensal microflora skin, urethra, mucous membranes, and genital tract. Isolates from patients with urinary tract infection (UTI) were reported, but pathogenic potential this species has not been defined yet. The aim study to determine whether C. could be etiological agent UTI analyze its antibiotic susceptibility. Urine samples cultured quantitatively according accepted laboratory procedures. identification bacterial isolates was carried out using...
Cognitive impairment is a significant clinical problem both in multiple sclerosis (MS) and systemic lupus erythematosus (SLE) patients. In MS cognitive dysfunction has been associated with brain atrophy total demyelinating lesion volume. SLE much less understood, its link to structural damage remains be established. The aim of this study was identify the relationship between subcortical gray matter volume SLE. We recruited 37 38 patients matched by age, disease duration educational level....
Bacteroides fragilis is an anaerobic bacterial species that involved in gynecological infections and pathology. The incidence of vaginal carriage largely unknown, order to study this, 120 pregnant women attending a general hospital for delivery were examined. Cultures positive eight these (6.6%). Interestingly, potential clonal relatedness could be demonstrated among several the nonenterotoxigenic B. strains. Among strains, only one produced metalloprotease enterotoxin. presence gene...
Differentiation of systemic lupus erythematosus (SLE) from multiple sclerosis (MS) can be challenging, especially when neuropsychiatric (NP) symptoms are accompanied by white matter lesions in the brain. Given lack discriminative power currently applied tools for their differentiation, there is an unmet need other measures that aid distinguishing between two autoimmune disorders. In this study we aimed at exploring whether brain atrophy could serve as markers differentiating MS and SLE....
<b><i>Objective:</i></b> Central nervous system (CNS) involvement in systemic lupus erythematosus (SLE) remains poorly understood. Damage within the CNS is driven by autoimmune response; however, immunopathophysiology of neuropsychiatric (NP) SLE multifactorial. Immune cell neurotrophin production could be neuroprotective against autoimmunity-driven damage, as has been shown multiple sclerosis. The aim this study was to establish whether immune associated with damage...
1. Aletaha D, Neogi T, Silman AJ, et al. Rheumatoid Arthritis Classification Criteria An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative. Rheum. 2010; 62, 9: 2569–2581, doi: 10.1002/art.27584. CrossRef Google Scholar
Primary Sjögren’s syndrome (pSS) is a chronic, autoimmune disease predominantly involving exocrine glands. Lymphadenopathy one of the possible symptoms pSS. It may also suggest development non-Hodgkin lymphoma (NHL), most severe complication pSS, or be symptom less common diseases, such as Kikuchi-Fujimoto (KFD), presented in this paper. an extremely rare, benign and self-limiting disorder, characterized by regional lymphadenopathy. <br /> This paper presents case previously unreported...
Objectives Biologics are medications widely applied in the management of inflammatory rheumatic diseases. The drugs were found to be effective but their application is associated with some disadvantages. Medication biologics relatively expensive, and Poland, it carried out specialized centers. study was designed evaluate various aspects satisfaction dissatisfaction Polish patients treated biologics. Material methods An anonymous questionnaire distributed 23 rheumatological centers involved...
<h3>Background</h3> The efficacy and safety profile of intravenous (IV) tocilizumab (TCZ) has been well established in patients (pts) with rheumatoid arthritis (RA). aim a subcutaneous (SC) TCZ dosing regimen is to provide the convenience patient home use self-administration. In BREVACTA study, primary endpoint was met by demonstrating superiority SC 162 mg q2w over placebo for ACR20 response at 24 weeks (ACR 2012). <h3>Objectives</h3> objective SUMMACTA study compare IV regimens pts adult...