A5072960118- Burn Injury Management and Outcomes
- Wound Healing and Treatments
- Surgical Sutures and Adhesives
- Dermatologic Treatments and Research
- Sleep and Wakefulness Research
- Orthopedic Surgery and Rehabilitation
- Reconstructive Surgery and Microvascular Techniques
- Injury Epidemiology and Prevention
- Pressure Ulcer Prevention and Management
- Disaster Response and Management
- Elbow and Forearm Trauma Treatment
- Sleep and related disorders
- Body Contouring and Surgery
- Prostate Cancer Treatment and Research
- Cardiac Arrest and Resuscitation
- Orthopedic Infections and Treatments
- Rabies epidemiology and control
- Restless Legs Syndrome Research
- Prostate Cancer Diagnosis and Treatment
- Restraint-Related Deaths
- Trauma and Emergency Care Studies
- Medical Malpractice and Liability Issues
- Olfactory and Sensory Function Studies
- Congenital limb and hand anomalies
- Hemostasis and retained surgical items
Heidelberg University
1988-2024
Berufsgenossenschaftliche Unfallklinik Frankfurt am Main
2021-2024
Goethe University Frankfurt
1974-2024
Ludwigshafen University of Business and Society
2018-2022
Klinikum Ludwigshafen
2016-2021
Berufsgenossenschaftliche Unfallklinik Ludwigshafen
2016-2020
Universität Hamburg
2020
University Medical Center Hamburg-Eppendorf
2020
Martini-Klinik
2020
The University of Texas Medical Branch at Galveston
2019
Bromelain-based Enzymatic Debridement has been introduced as an additional concept to the burn surgeon's armamentarium and is best indicated for mid-to deep dermal burns with mixed patterns. Increasing evidence published focusing on special regions settings well limitations of improve patient care. To better guide in view increasing experience, there a need update formerly consensus guidelines user-orientated recommendations, which were last produced 2017. A multi-professional expert panel...
Abstract In sepsis and burns, ascorbic acid (AA) is hypothesized advantageous during volume resuscitation. There uncertainty regarding its safety dosing. This study evaluated high dose AA (HDAA: 66 mg/kg/h for 24 hours) versus low (LDAA: 3.5 g/days) administration the first hours in severely burned adults. We conducted a retrospective comparing fluid before after switching from to HDAA A total of 38 adults with burns >20% TBSA, who received either or LDAA were included this study....
Abstract For nearly two decades, Negative Pressure Wound Therapy (NPWT) has been used for temporary wound coverage as well bed preparation. The addition of instillation and dwell time an adjunct to NPWT (NPWTi‐d) enables cleaning improved granulation. Thirty patients with different types colonised wounds (traumatic, surgical, chronic) were treated NPWTi‐d using saline instillation. Patient data, microbiological data characteristics collected analysed. Endpoints bacterial decontamination...
Secondary lymphedema (SL)is a frequent and devastating complication of modern oncological therapy filarial infections. A lack reliable preclinical model to investigate the underlying mechanism clinical stage progression has limited development new therapeutic strategies. Current first line treatment shown be merely symptomatic relies on lifetime use compression garments decongestive physiotherapy. In this study, we present secondary in 35 rats using pre- intraoperative fluorescence-guided...
Enzymatic debridement (ED) has become a reliable tool for eschar removal. Although ED application is simple, wound bed evaluation and therapy decision post-intervention are prone to subjectivity failure. Experience in might be the key, but this not been proven yet. The aim of study was assess interrater reliability (IR) as well impact experience. In addition, authors introduce video assessment valuable post-ED decision-making education. A video-based survey conducted among physicians with...
Introduction Severe thermal trauma to the hand can result in major impairment and reduced function due defective healing or even extremity loss. Full-thickness injuries frequently incur exposure of tendons bone require an early stable coverage with soft tissue transplants allow for rapid induction exercise preserve structures function. Free transfer after is a rare indication, safety, management, outcome free flap surgery severe acute burn remains underreported. Methods Patients primary...
Despite overall advances in burn therapy, wound infection remains one of the leading causes morbidity and mortality patients with severe injuries. This prospective, multicenter, noncomparative clinical trial was conducted to assess efficacy safety Prontosan® Wound Gel X (PWX), a gel containing polihexanide betaine, for moistening cleansing deep tissue wounds requiring split-thickness skin grafting. Patients partial or full thickness grafting were treated evaluate its tolerability as well...
Background Early reconstruction of burn sequelae the hand can be challenging owing to high goals for functional and aesthetic outcome. A variety reconstructive procedures with ascending levels complexity exists warrants careful indication. Methods In this case series, main techniques defects are described, illustrated, discussed: split thickness skin grafting (STSG) fibrin glue, dermal matrices STSG, distant random pattern (abdominal bridge) flap, pedicled flap (superficial circumflex iliac...
The effects of di-n-propylacetic acid (DPA) on sleep, for some years used as an anticonvulsive drug, has been investigated in 11 healthy volunteers using all-night sleep EEG recordings. DPA acts by enhancement the gamma-aminobutyric (GABA) level brain. Its influence seemed to be interest account metabolic relationship GABA other short chain fatty acids. After short-term application only a shortening time fall asleep and waking could found, whereas under long-term administration decrease deep...
Surgical treatment of deep partial thickness to full burn wounds by knife has been the undisputed standard care and was one key point in surgical medicine for decades. Recently, it gets more challenged Bromelain-based enzymatic wound debridement (ED) as technique non-surgical, selective eschar removal. Although literature on ED is increasing constantly cannot comprise rapid progress that made clinical application ED. To outline current state art ED, recent well experience summarized main...
Abstract Background Microsurgery is an indispensable tool of upper extremity reconstruction addressing defect coverage and the restoration function. Perioperative anticoagulation antiplatelet therapy are controversially discussed with impact on microsurgical outcome, but without clear evidence. This study aims to evaluate perioperative in reconstruction. Methods All eligible patients treated between January 2000 July 2014 were included a comparative analysis define superior regime...
Abstract Herein, we report the synthesis of seleno‐substituted chromenes from selenoalkynes and phenols. In this cascade reaction, applied gold catalyst not only functions as a π‐acid, but also Lewis acid, enabling propargylic substitution in first step to connect oxygen carbon bond. Under optimal reaction condition total 26 were accessible by modular access. During scale up experiments, hydrolysis vinylselenium substructure corresponding chromenones was observed. By revisiting electron‐rich...