- Chronic Myeloid Leukemia Treatments
- Chronic Lymphocytic Leukemia Research
- Liver Disease Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Eosinophilic Disorders and Syndromes
- Reproductive tract infections research
- Sexual function and dysfunction studies
- Acute Lymphoblastic Leukemia research
- Urinary Tract Infections Management
- Pancreatic and Hepatic Oncology Research
- Diet and metabolism studies
- Lymphoma Diagnosis and Treatment
- Connective tissue disorders research
- Craniofacial Disorders and Treatments
- Cardiovascular and Diving-Related Complications
- BRCA gene mutations in cancer
- Diabetes and associated disorders
- COVID-19 and healthcare impacts
- Protein Degradation and Inhibitors
- Sympathectomy and Hyperhidrosis Treatments
- Urinary and Genital Oncology Studies
- Fatty Acid Research and Health
- Palliative Care and End-of-Life Issues
- Pediatric Urology and Nephrology Studies
- Restless Legs Syndrome Research
University of California, Irvine
2021-2024
University of Turin
1989-2022
Roger Williams Medical Center
2021
Providence College
2021
Boston University
2021
Lifespan
2021
University of Balamand
2021
Hospital do Rim e Hipertensão
2018-2020
Universidade Federal de São Paulo
2018
Instituto de Biomedicina de Sevilla
2015
Restless legs syndrome (RLS) often presents with paresthesias and dysesthesisas. We have investigated the prevalence clinical features of RLS in a cohort patients referred for suspicion peripheral neuropathy (PN). Sixty-four sensory symptoms, 101 age-matched controls were prospectively evaluated RLS, PN causes both conditions. In 64 (60 +/- 14 years), none RLS. Forty-one had sensori-motor which 22 definite (54%). When excluding other 8 41 associated (20%). The proportion healthy was 10%,...
Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis, with 5-year overall survival rate of 10%. In November 2018, NCCN recommended that all patients PDAC receive genetic counseling (GC) and germline testing regardless family history. We hypothesized were more likely to be referred for after this change the guidelines, presumed predictive factors, compliance would further improved following implementation hereditary cancer clinic (HCC).
Abstract Background and Objectives The SARS‐COVID‐19 pandemic significantly limited healthcare access. We sought to evaluate whether California's lockdown in March 2020 affected staging time treatment of pancreatic ductal adenocarcinoma (PDAC). hypothesized that patients diagnosed after the would have longer higher stage at presentation. Methods retrospectively identified categorized 1294 presenting five University California systems with a new diagnosis PDAC into “pre‐lockdown”...
Summary. The t(8;21) (q22;q22) translocation is a recurring chromosomal abnormality observed in about 20‐40% of AML patients with subtype FAB M2 (AML‐M2). molecular facet this represented by the formation new hybrid gene, AML1‐ETO, which regularly transcribed chimaeric mRNA and translated into fusion protein believed to have key role pathogenesis type leukaemia. We looked for presence AML1‐ETO transcripts, RT‐PCR, 49 unselected affected AML‐M2 diagnosed at various Italian Institutions. A...
Objectives. Self-administered vaginal swabs were used to determine the prevalence of Chlamydia trachomatis in a population under 25 years age order evaluate if this is an acceptable and accurate method compared traditional cervical swabs. Methods. Patients asked perform double self-administered swab prior swab. One self-collected was with AMPLIFIED CT DNA PROBING (GENPROBE bioMérieux) that based on probe against amplified target for identification ribosomal RNA. The remaining two processed...
Parts of the Bcr/Abl hybrid transcript supposed to be important for its transforming ability were sequenced in a series CML blast crises, order evaluate possible presence alterations responsible disease transition from chronic acute phase. In addition, N and Ki-ras as well p53 involvement was investigated by exploring their structure expression same patients. We used traditional types molecular analysis including Southern Northern blot, together with methods that allow rapid detection point...
Chlamydia trachomatis (C.t.) infection is one of the most prevalent sexually transmitted disease in Europe and developed countries. The main biological features pathogenic mechanisms C.t. are summarized this review. It usually occurs without symptoms often goes undiagnosed. If untreated, it can cause severe consequences for women, including pelvic inflammatory (PID), ectopic pregnancy tubal infertility. Several studies have found that more common among young women <25 years old, with...
S ummary . The Philadelphia chromosome (Ph 1 ) is present in 95% of chronic myelogenous leukaemias (CML) and 15% acute lymphoblastic (ALL). This cytogenetic marker due to a t(9;22) translocation, which causes rearrangement the ABL oncogene. In order better define relationship between type genomic rearrangement, variant protein expressed haematological phenotype, series Ph l ‐positive leukaemias, both myeloblastic (AML) lymphoblastic, several CML lymphoid blast crises have been analysed at...
As the number of kidney transplants continues to rise, so does and complexities surgical-related complications, which may be associated with increased morbidity potentially graft loss. Ureteral stenosis, most prevalent urological complication, require diverse techniques for surgical correction depending on several recipient abnormalities. Here we report clinical outcomes a 62-year-old man posttransplant pyeloureterostomy stricture successfully treated ureterocalicostomy after lower pole...
Abstract: Repeated PCR analysis was performed on bone marrow and/or peripheral blood samples from 4 CML patients in complete cytogenetic remission during treatment with IFN‐α. Two became PCR‐negative. One negative for the analyses carried out 9th to 30th months, but reverted positivity 10 months after IFN reduced 1.5 × 6 IU/day 1 IU and given alternate days. Although dose again raised 3 IU/day, 8 later her cells were still PCR‐positive, remained persistently Ph'‐negative. Another patient...