A5054608884- Advanced Fiber Optic Sensors
- Photonic and Optical Devices
- Photonic Crystal and Fiber Optics
- Advanced Fiber Laser Technologies
- Advanced MIMO Systems Optimization
- Ultrasonics and Acoustic Wave Propagation
- Cancer Genomics and Diagnostics
- Spectroscopy and Laser Applications
- Acoustic Wave Resonator Technologies
- Advanced MEMS and NEMS Technologies
- Advanced Chemical Sensor Technologies
- Analytical Chemistry and Sensors
- Plasmonic and Surface Plasmon Research
- Cellular and Composite Structures
- Electrical and Bioimpedance Tomography
- Microwave Imaging and Scattering Analysis
- Photorefractive and Nonlinear Optics
- Advanced Measurement and Detection Methods
- Ultrasound Imaging and Elastography
- Acoustic Wave Phenomena Research
- Genetic factors in colorectal cancer
- Circular RNAs in diseases
- Wireless Communication Networks Research
- Nerve injury and regeneration
- Cancer-related molecular mechanisms research
Burning Rock Biotech (China)
2020-2025
Henan University
2024
State Key Laboratory of Metastable Materials Science and Technology
2023-2024
Yanshan University
2023-2024
Chengdu University of Technology
2024
PLA Army Engineering University
2021-2023
Xiamen University
2005-2023
Northwestern Polytechnical University
2020-2021
Southern Medical University
2016-2020
NARI Group (China)
2020
Significance Spinal cord injury (SCI) is a debilitating medical condition with no cure at present time. In this study we have discovered that biodegradable material, chitosan, when loaded with, Neurotrophin-3 (NT3), allowed for slow release of neural trophic factor, providing an optimal microenvironment regeneration. NT3-chitosan, inserted into 5 mm gap completely transected and excised rat thoracic spinal cord, elicited robust activation endogenous stem cells forming functional networks,...
In this paper, high-order LP modes based Sagnac interference for temperature sensing are proposed and investigated theoretically. Based on the specific excited through mode selective couplers (MSCs), we design a stress-induced Panda-type few-mode fiber (FMF) supporting 4 construct interferometer to achieve highly sensitive sensor. The performances of different (LP
In this study, PMI foam and aluminum are used as reinforcement materials for filling the cells of carbon fiber-reinforced composite square honeycomb sandwiches (CSHSs), forming two new sandwich structures, namely, foam-reinforced CSHS (PRCSHS) (AFRCSHS). The impact resistance residual flexural performance composites is compared by using low-velocity (LVI) three-point bending (3 PB) experiments. different energy levels 25 J, 50 65 100 J applied. failure process mechanism analyzed a...
Abstract In this paper, a fiber optic glucose concentration sensor based on cascaded Mach–Zehnder interferometers (CMZIs) was proposed and experimentally verified. Two single-mode fibers (SMFs) with slightly different tapering lengths as well free spectral ranges (FSRs) were obtained through the melt-drawn cones technique then together to achieve Vernier effect (VE). Experimental results showed that measurement sensitivity of single tapered SMF 0.0494 nm (mmol l −1 ) . Furthermore, SMFs...
Abstract Methane gas, due to its high flammability, is convenient for people’s daily lives, but flammability poses safety hazards. tends explode when mixed with air. Therefore, it particularly important be able effectively detect methane gas concentrations. A new sensor presented in this paper. It extremely sensitive the reaction of gas. consists two fiber Sagnac interferometer (SI) loops, which utilize vernier effect. The SI loops remain parallel. optical structure effective sensing loop...
Abstract Background: Liquid biopsy stands as a valuable tool in the field of precision medicine, with its utility extending across cancer detection, recurrence monitoring, and treatment selection. However, achieving desired level sensitivity often requires access to tumor tissue, which can be limiting factor. Recent studies have shown that analyzing methylation patterns circulating DNA (ctDNA) enables sensitive accurate measurement burden tissue-independent manner, thus opening up new...
Abstract Background: Multiomic circulating tumor DNA (ctDNA) assays offer several benefits over tumor-dependent ones, including being more rapid, less invasive, and cost-effective for monitoring recurrence or therapy response through serial testing. Despite these advantages, identifying ultra-low frequency ctDNA alterations, whether genetic epigenetic, from limited input material is highly challenging. Furthermore, complex are often susceptible to experimental computational variables...
Abstract Dual-parameter sensors are highly competitive and commercially valuable in industrial, medical, biochemical fields. A two-parameter surface plasmon resonance (SPR) sensor with an ultra-wide measuring range is proposed, which can measure both refractive index (RI) temperature (T). The structure a right-angle side-polished type, Ag+Au deposited on one for RI measurement Ag+Au+polydimethylsiloxane (PDMS) the other T measurement. combination of side polishing gold-silver composite film...
Chronic obstructive pulmonary disease (COPD) is an incomplete, reversible with progressive inflammation obstruction in airways. This study aims to explore the regulatory mechanism of hypoxia-inducible factor-1α (HIF-1α) inflammatory response and progression COPD.71 bronchoalveolar lavage fluid (BALF) samples were collected, including 59 from COPD patients (COPD group) 12 normal function (control group). The mRNA protein levels HIF-1α epidermal growth factor receptor (EGFR) BALF detected by...
Utilization of the vernier effect in fiber optic interferometers represents latest approach to enhance sensitivity and resolution sensors. In this paper, Vernier Sagnac interference (SI) with a double D-shaped photonic crystal (PCF) was proposed for methane gas sensing. The sensing arm SI composed PCF which coated cryptophane-A film, while polarization maintaining (PM-PCF) is used as reference arm. were cascaded parallel generate effect. influence structural parameters on performance...
Purpose Knowledge of dielectric properties malignant human tissues is necessary for the recently developed magnetic resonance (MR) technique called MR electrical property tomography. This may be used in early tumor detection based on obvious differentiation between normal and tissues. However, scale Larmor frequencies are not completely available literature. In this study, authors focused only colorectal tissue. Methods The 504 samples excised from 85 patients were measured using precision...
In this study, a three-rib intersecting composite diamond honeycomb structure is fabricated by interlocking technology. The mechanical properties of the interlocked (CIDH) and corresponding sandwich (CIDHSS) are experimentally tested. stiffness, strength, failure characteristics CIDH CIDHSS analyzed. results show that has better than Kagome square honeycombs. edge effect limits compressive strength stiffness CIDH. Debonding main mode both bending CIDHSS. reinforced plate added to effectively...
A novel highly sensitive D-shaped photonic crystal fiber-based surface plasmon resonance (PCF-SPR) sensor for dual parameters of refractive index and temperature detecting is proposed. PCF cladding polishing provides a D-shape design with gold (Au) film coating (RI) sensing (Core 1) composite silver (Ag) polydimethylsiloxane (PDMS) 2). Comsol Multiphysics 5.5 used to simulate the proposed by finite element method (FEM). The numerically results maximum wavelength sensitivities (WSs) 51,200...
Abstract A novel aldo-keto reductase Tm1743 characterized from Thermotoga maritima was explored as an effective biocatalyst in chiral alcohol production. Natural catalyzes asymmetric reduction of ethyl 2-oxo-4-phenylbutyrate (EOPB) at high efficiency, but the production of, (S)-2-hydroxy-4-phenylbutyrate ((S)-EHPB), which is less desirable, preferred with enantiomeric excess ( ee ) value 76.5%. Thus, altering enantioselectivity to obtain more valuable product (R)-EHPB for angiotensin drug...
The aim of this study was to explore the role microRNA-143-3p (miR-143-3p) in cartilage injury, and investigate possible underlying mechanism.A chondrogenic differentiation cell model established bone marrow mesenchymal stem cells (BMSCs). mRNA expression levels runt-related transcription factor 2 (RUNX2), miR-143-3p morphogenetic protein (BMPR2) BMSCs were detected by quantitative Real Time-Polymerase Chain Reaction (qRT-PCR) after 0 d, 5 d 10 respectively. Mesenchymal (MSCs) transfected...
Abstract A wide measurement range plasmonic refractive index (RI) sensor based on side-polished photonic crystal fiber (PCF) was proposed and studied in this paper. composite film containing an Au layer a TiO 2 coated the polished surface of PCF to excite modulate plasmon resonance (SPR) effect. The sensing characteristics were analyzed using finite element method (FEM). Numerical results showed that performances significantly improved through introducing unique optoelectronic material film....
Terbium scandium aluminum garnet crystals (Tb3Sc2Al3O12, TSAG) have excellent optical comprehensive properties with unique competitive advantages in the Verdet constant and anti-laser damage threshold. However, component segregation will easily occur during growth of TSAG crystal distribution habits elements not been systematically studied. A series different compositions were grown by Czochralski method this work. The behaviors Sc3+ Al3+ discussed, relationship between cracking structure...