A5101624587- Liver Disease Diagnosis and Treatment
- Analytical Chemistry and Chromatography
- Metabolomics and Mass Spectrometry Studies
- Nutritional Studies and Diet
- Diet, Metabolism, and Disease
- Advanced Chemical Sensor Technologies
- Diet and metabolism studies
- Lipid metabolism and disorders
- Pharmacological Effects of Natural Compounds
- Membrane Separation Technologies
- Folate and B Vitamins Research
- Adipokines, Inflammation, and Metabolic Diseases
- Sphingolipid Metabolism and Signaling
- Photonic Crystal and Fiber Optics
- Molecular Sensors and Ion Detection
- Immune Response and Inflammation
- Graphene research and applications
- Water Treatment and Disinfection
- Drug Transport and Resistance Mechanisms
- Ovarian function and disorders
- Photonic and Optical Devices
- Enzyme Catalysis and Immobilization
- Mass Spectrometry Techniques and Applications
- Lipoproteins and Cardiovascular Health
- Genomics, phytochemicals, and oxidative stress
Beijing Forestry University
2025
Huazhong University of Science and Technology
2023-2025
Tongji Hospital
2023-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2025
Anhui University of Science and Technology
2024
Tianjin Medical University
2024
Jinan University
2024
South China University of Technology
2023
State Key Laboratory of Metastable Materials Science and Technology
2023
Central South University
2023
N-Nitrosodimethylamine (NDMA), a member of group probable human carcinogens, has been detected as disinfection byproduct (DBP) in drinking water supplies Canada and the United States. To comprehensively investigate occurrence possible nitrosamines supplies, liquid chromatography-tandem mass spectrometry technique was developed to detect both thermally stable unstable nitrosamines. This consisted solid-phase extraction (SPE), chro matography (LC) separation, tandem quadrupole linear ion trap...
Formation of nine N-nitrosamines has been investigated when seven different source waters representing various qualities were each treated with eleven bench-scale disinfection processes, without addition nitrosamine precursors. These treatments included chlorine (OCl−), chloramine (NH2Cl), dioxide (ClO2), ozone (O3), ultraviolet (UV), advanced oxidation processes (AOP), and combinations. The total organic carbon (TOC) the ranged from 2 to 24 mg·L−1. disinfected water samples untreated...
Dietary fiber is an integral part of a healthy diet, but questions remain about the mechanisms that underlie effects and causal contributions gut microbiota. Here, we performed 6-week exploratory trial in adults with excess weight (BMI: 25-35 kg/m2) to compare high-dose (females: 25 g/day; males: 35 g/day) supplement fermentable corn bran arabinoxylan (AX; n = 15) microbiota-non-accessible microcrystalline cellulose (MCC; 16). Obesity-related surrogate endpoints biomarkers host-microbiome...
Background and purpose: Silymarin, a standardized extract of the milk thistle seeds, has been widely used to treat chronic hepatitis, cirrhosis, other types toxic liver damage. Despite increasing studies on action silymarin its major active constituent, silybin in their therapeutic properties against insulin resistance, diabetes hyperlipidaemia vitro vivo, mechanism underlying remains unclear. Experimental approach: C57BL/6 mice were fed high-fat diet (HFD) for 3 months induce obesity,...
Abstract Polycystic ovary syndrome (PCOS) is an endocrine disorder that occurs in women of reproductive age. Anovulation caused by abnormal follicular development still the main characteristic PCOS patients with infertile. Granulosa cell (GC) important part microenvironment, dysfunction which can affect development. Increasing evidence indicates exosomal miRNAs derived from fluid (FF) play critical roles during PCOS. However, fluid-derived a pivotal role controlling granulosa function and...
Abstract Autotaxin catalyzes the formation of lysophosphatidic acid, which stimulates tumor growth and metastasis decreases effectiveness cancer therapies. In breast cancer, autotaxin is secreted mainly by adipocytes, especially when stimulated inflammatory cytokines produced tumors. this work, we studied effects an ATX inhibitor, GLPG1690, in phase III clinical trials for idiopathic pulmonary fibrosis, on responses to radiotherapy chemotherapy a syngeneic orthotopic mouse model cancer....
Climate change has intensified the frequency of extreme drought events in desert ecosystems, accompanied by uneven distribution annual precipitation. Whether precipitation at different phenophases have equivalent impacts on plants is an unverified topic, yet it crucial for understanding mechanisms vegetation adaptation to changes This study focuses typical plant Artemisia ordosica and employs situ control experiments using rain shelters simulate (30 consecutive days removal) three...
Climate change has intensified the frequency of extreme drought events in desert ecosystems, accompanied by uneven distribution annual precipitation. Whether precipitation at different phenophases have equivalent impacts on plants is an unverified topic, yet it crucial for understanding mechanisms vegetation adaptation to changes This study focuses typical plant Artemisia ordosica and employs situ control experiments using rain shelters simulate (30 consecutive days removal) three...
Canldiapolipoprotein (apo) B plays an obligatory role in the assembly and secretion of hepatic triglyceride-rich lipoproteins.Investigation truncated human apoB variants associated with hypobetalipoproteinemia has suggested that both size apoB-containing lipoproteins may be reduced by carboxyl-terminal truncation.To examine carboxyl terminus lipoproteins, we have generated rat hepatoma McA-RH7777 cells synthesize secrete full- length apoBl00 forms B94, B88, B80, B72, B60.In resulting...
Exposure to cadmium (Cd), a toxic metal, is epidemiologically linked nonalcoholic steatohepatitis (NASH) in humans. However, the role of Cd NASH remains be fully elucidated. This study employed novel murine model investigate effects chronic low-dose on hepatic pathology and its underlying mechanisms. characterized by lipid accumulation, extensive cell death, persistent inflammation liver. We found that treatment with drinking water (10 mg/L) for 6 or 12 weeks significantly boosted fat...
To improve the anti-biofouling properties of membranes, Ag-embedded nano-sized titanium dioxide (Ag-n-TiO<sub>2</sub>) particles were utilized as biocidal agents to modify polyvinyl chloride (PVC) membranes.
Background Depression and type 2 diabetes (T2D) are serious public health problems with irreversible consequences a significant economic burden on the healthcare system. Previous studies have suggested that blood urea nitrogen (BUN) was inversely longitudinally associated incidence of depression in adults, but few well-designed examined effects status T2D full range relationship between BUN depression. Methods The analysis sample consisted adults aged≥20 years from 2007-2014 National Health...