- Spine and Intervertebral Disc Pathology
- Medical Imaging and Analysis
- Cervical and Thoracic Myelopathy
- Spinal Fractures and Fixation Techniques
- Spinal Hematomas and Complications
- Traditional Chinese Medicine Analysis
- Pelvic and Acetabular Injuries
- Mycobacterium research and diagnosis
- HER2/EGFR in Cancer Research
- Reconstructive Facial Surgery Techniques
- Reconstructive Surgery and Microvascular Techniques
- Gastric Cancer Management and Outcomes
- Anesthesia and Pain Management
- Tuberculosis Research and Epidemiology
- Management of metastatic bone disease
- Advanced Breast Cancer Therapies
- Orthopaedic implants and arthroplasty
- Head and Neck Surgical Oncology
- Protein Tyrosine Phosphatases
- Neurological Disease Mechanisms and Treatments
- Musculoskeletal pain and rehabilitation
- Microbial bioremediation and biosurfactants
- Indoor Air Quality and Microbial Exposure
- Sarcoma Diagnosis and Treatment
- Pharmacological Effects of Natural Compounds
Hunan Cancer Hospital
2021-2025
Central South University
2021-2025
University of Electronic Science and Technology of China
2025
Wenzhou Medical University
2023
Wenzhou Central Hospital
2023
Army Medical University
2007-2022
Xinqiao Hospital
2007-2022
Zhuzhou Central Hospital
2022
Shanghai Laser Technology Institute
2019
Xuzhou Cancer Hospital
2018
Endoscopic surgeries have been attempted in the field of lumbar decompression and fusion surgery past decade. Percutaneous endoscopic interbody (PELIF) is a new-emerging technique taking advantages an anatomical (Kambin's triangle) to achieve simultaneous under visualization. The purpose this study evaluate feasibility safety PELIF with general anesthesia neuromonitoring.The authors present details neuromonitoring. first 7 consecutive patients treated minimum 2 year's follow-up were...
A fluorescence particle spectrometer (FPS) for real-time measurement of the spectra aerosol particles in size range 1-10 w m diameter is reported. The prototype FPS has a sufficiently high sample rate (from 5 to 28 l/min 3.5 11 particles) measure within buildings at practical rates 1 up 600 per minute). Previously reported bioaerosol detectors single (Pan et al., Opt. Lett ., 24, 116-118 (1999); Hill Field Anal. Chem. Tech 3, 221-239 (1999)) were unable ambient environment; air containing...
Introduction: Trastuzumab emtansine(T-DM1) and trastuzumab deruxtecan (T-DXd, formerly DS-8201a), the human epidermal growth factor receptor 2 (HER2)-targeted antibody-drug conjugate (ADC), are commonly used in metastatic breast cancer. However, their real-world safety profile has not been adequately compared. Objective: We aimed to investigate adverse event (AE) of T-DM1 T-DXd reported by US Food Drug Administration Adverse Event Reporting System (FAERS). Methods: All indications were...
The local hatchet flap has been used to reconstruct skin defects of the face with satisfactory results. Cosmetically, it advantages over other flaps when are located in special areas such as eyelid.The purpose this study was examine application for facial defect reconstruction, especially cases where reconstruction is classically difficult cosmetic and functional rehabilitation.We report an illustrated case series. Results. In study, all four achieved results using flap.The effective simple...
The apoptosis of nucleus pulposus (NP) cells reduces the number in intervertebral disc tissue, resulting degeneration (IDD). MicroRNAs (miRNAs) play an important regulatory role abnormal cell proliferation and apoptosis.The miR-27a-3p expressions degenerative NP tissue were measured via qPCR. impacts on human evaluated by flow cytometry assays, MTT western blot analyses. In addition, target scan luciferase reporter assay applied to confirm that RASSF5 was directly binding miR-27a-3p. Western...
The increasing emergence of bacterial strains with high VAN MICs (BS H – V AN– M ), such as Enterococcus faecalis , faecium Staphylococcus aureus epidermidis and Streptococcus bovis results in growing concern that is not effective against these isolates. Due to the limited data on BS H–VAN–M application limits drugs currently considered be for exploration “new usages old drugs” reasonable improve maximize efficacy existing antibiotics. This study aimed construct a novel dosing strategy mine...
The family of Eph receptor tyrosine kinases and their Ephrin ligands system constitutes a bidirectional signaling pathway. Eph/Ephrin coordinate wide spectrum pathologic processes during development, metastasis, prognosis, drug resistance angiogenesis in carcinogenesis. Chemotherapy, surgery radiotherapy are the most commonly used clinical treatments for primary bone tumors. Therefore, surgical resection is often unable to completely eliminate tumor, this main cause metastasis postoperative...
To investigate the clinical results and complication prevention of minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) in treatment single-segment severe spinal stenosis (LSS).The data 112 patients with LSS treated MIS-TLIF between January 2010 2017 were retrospectively analyzed. There 43 males 69 females, aged 52-81 years, an average age 65.3 years. The disease duration ranged from 4 to 126 months, 10.5 months. Clinical manifestations: 104 cases low back pain, 91 nervous...
BACKGROUND The local hatchet flap has been used to reconstruct skin defects of the face with satisfactory results. Cosmetically, it advantages over other flaps when are located in special areas such as eyelid. OBJECTIVE purpose this study was examine application for facial defect reconstruction, especially cases where reconstruction is classically difficult cosmetic and functional rehabilitation. METHODS We report an illustrated case series. RESULTS In study, all four achieved results using...
Introduction & Objective: Incretin receptor agonists have emerged as leading treatments for obesity. Despite the efficacy of these drugs, they can negatively impact body composition, raising interest in complementary mechanisms. In a Phase 1b trial, our oral apelin agonist azelaprag preserved muscle mass, quality, and protein synthesis during bed rest shifted plasma proteome into state associated with endurance exercise, including higher basal metabolic rate VO2 max. Accordingly, we...
Abstract Introduction: Trastuzumab emtansine(T-DM1) and trastuzumab deruxtecan (T-DXd, formerly DS-8201a), the human epidermal growth factor receptor 2 (HER-2)-targeted antibody-drug conjugate (ADC), are commonly used in metastatic breast cancer. However, their real-world safety profile has not been adequately compared. Objective We aimed to investigate adverse event (AE) of T-DM1 T-DXd reported by US Food Drug Administration Adverse Event Reporting System (FAERS). Methods All indications...
To analyze the clinical characteristics of AIDS with dTSM, especially in patients poor prognosis.One hundred and seventy were enrolled this single-center retrospective study. The epidemiological characteristics, manifestations, laboratory tests, imaging examination, treatment outcome collected. Logistic regression analysis was used to estimate risk mortality dTSM. predictive value evaluated using receiver operating characteristic (ROC) curve.From 2015 2022, incidence dTSM Wenzhou region...
Treatment strategies and preventive methods for drug-resistant Helicobacter pylori infection