A5105407477- Electronic Packaging and Soldering Technologies
- Antibiotics Pharmacokinetics and Efficacy
- Landslides and related hazards
- Bone Tissue Engineering Materials
- Enzyme function and inhibition
- 3D IC and TSV technologies
- Geotechnical Engineering and Analysis
- Drilling and Well Engineering
- Thermal properties of materials
- Anesthesia and Neurotoxicity Research
- Antifungal resistance and susceptibility
- Antibiotic Resistance in Bacteria
- Synthesis and properties of polymers
- Hydraulic Fracturing and Reservoir Analysis
- Fungal Infections and Studies
- Rock Mechanics and Modeling
- Cancer Genomics and Diagnostics
- Cancer, Stress, Anesthesia, and Immune Response
- Civil and Geotechnical Engineering Research
- Calcium Carbonate Crystallization and Inhibition
- Curcumin's Biomedical Applications
- Oil and Gas Production Techniques
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Calcium signaling and nucleotide metabolism
- Phosphodiesterase function and regulation
Shanghai University of Electric Power
2011-2025
Chongqing Jiaotong University
2025
Hebei Medical University
2025
Second Hospital of Hebei Medical University
2025
Huazhong University of Science and Technology
2008-2024
Hangzhou Medical College
2017-2024
Zhejiang Provincial People's Hospital
2016-2024
Soochow University
2022-2024
Xi'an University of Science and Technology
2018-2023
Hunan Cancer Hospital
2018-2023
Accumulating evidence has demonstrated that oxidative stress is associated with depression. Our present study aimed at investigating the antidepressant effect and possible mechanisms of curcumin (CUR) in chronic unpredictable mild stress- (CUMS-) induced depression model rats. After exposure to CUMS for four weeks, rats showed depressive-like behavior, behaviors CUMS-treated were successfully corrected after administration CUR. In addition, CUR could effectively decrease protein expression...
Doxorubicin (DOX)-induced neurotoxicity is widely reported in previous studies. Oxidative stress has been validated as a critical event involved DOX-induced neurotoxicity. As selective autophagy adaptor protein, p62 to regulate Keap1-Nrf2-ARE antioxidant pathway response oxidative stress. Curcumin (CUR) relieves depressive-like state through the mitigation of and activation Nrf2-ARE signaling pathway. However, exact mechanism CUR alleviating still unknown.The rats were randomly divided into...
To investigate the diffusion law of ultrafine cement slurry (UCS) with different water–cement ratios in tunnel second lining cracks during grouting, grouting was carried out by experimental and theoretical analysis methods this study. Through collection data experiment time history, morphological characteristics based on viscosities were obtained, which divided into three patterns: circular zone, excessive elliptical zone. Furthermore, spatiotemporal variation rules radius secondary obtained...
Silibinin is mixture of flavonolignans extracted from milk thistle and often has been used in the treatment acute chronic liver disorders caused by toxins, drug, alcohol hepatitis gall bladder for its antioxidant hepatoprotective properties. Areas covered: However, increasing evidence suggest that silibinin not solely limited these diseases. Further research suggests silymarin may function diversely serve as a novel therapy cancer therapy, such lung cancer, prostatic colon breast...
<title>Abstract</title> Acute myeloid leukemia (AML) as the second most common hematological malignancy remains currently incurable. In this study, we found protein disulphide isomerase family (PDIs) was expressed in primary cells, with particular emphasis on ERP5 and ERP57. The compound PACMA31 demonstrated ability to inhibit proliferation, enhance differentiation, exacerbate oxidative stress, induce apoptosis AML cells. RNA sequencing analysis revealed that impeded proliferation of cells...
Infections due to meropenem-nonsusceptible bacterial strains (MNBSs) with meropenem minimum inhibitory concentrations (MICs) ≥ 16 mg/L have become an urgent problem. Currently, the optimal treatment strategy for these cases remains uncertain some limitations of currently available mono- and combination therapy regimens. Meropenem monotherapy using a high dose 2 g every 8 h (q h) 3-h traditional simple prolonged-infusion (TSPI) has proven be helpful infections MNBSs MICs 4-8 but is limited...
The current study evaluated the cardioprotective activity of genistein in cases doxorubicin-(Dox) induced cardiac toxicity and a probable mechanism underlying this protection, such as an antioxidant pathway tissues. Animals used were categorized into four groups. first group was treated with sodium carboxymethylcellulose (0.3%; CMC-Na) solution. second received Dox (3.0 mg/kg, i.p.) on days 6, 12, 18, 24. third fourth groups (3 24 protective doses (100 [group 3] 200 4] mg/kg/day, p.o.) for...
The acidic tumor microenvironment (TME) is unfriendly to the activity and function of immune cells in TME. Here, we report inorganic nanozymes (i.e., SnSe NSs) that mimic catalytic lactate dehydrogenase degrade pyruvate, contributing metabolic treatment tumors. As found this study, NSs successfully decreased levels tumors, as well reduced acidity. This associated with activation response T cells, thus alleviating immunosuppressive environment More importantly, nanozyme inhibited growth...
Abstract In view of the problem heat accumulation in electronic devices, development new composites with high thermal conductivity (TC) is current research focus. Nowadays, improving TC often lead to inevitable deterioration mechanical properties materials. this work, E‐functionalized boron nitride nanosheets ( f ‐BNNS)/liquid crystal monomer (LCM)/Epoxy‐thiol films were prepared by using flexible epoxy‐thiol polymer as matrix and LCM ‐BNNS fillers via voltage orientation molding. The...
Purpose This paper aims to offer a convenient method develop an oven recipe for specific soldering profile in reflow process. The is devised quickly achieve proper shape and heating factor Q η , measure of success high reliability the solder joints reflowed. Design/methodology/approach An in‐depth analysis mechanism some experiments process are performed research on how realize were conducted. Findings Heating demonstrate that combinatorial parameters based feasible do thermal profiling....
Oxidative stress enhances tumor invasion and metastasis in brain cancer. The activation of divalent metal transporter 1 (DMT1), which is regulated by glutamate receptors, can result the increase oxidative risk cancer development. Propofol, an anesthetic with antioxidant capacity, has been shown to decrease several different types However, underlying mechanism remains unclear. Therefore, present study aimed elucidate suppression glioma cells propofol. It was hypothesized that propofol may...
Abstract Flexible epoxy‐dispersed liquid crystal membranes (EDLC‐ v membranes) with high thermal conductivity were successfully prepared by using of voltage orientation molding. Liquid monomer (LCM) was uniformly dispersed into flexible epoxy polymers cured trimethylolpropane tris(3‐mercaptopropionate) (TTMP) or pentaerythritol tetra(3‐mercaptopropionate) (PETMP). In‐plane (TC // ) EDLC‐ reached to 1.47 W m −1 K LCM content 30 wt%, which 5.65 times higher than that without (0.26 ). In...