Zhengping Zhu

ORCID: 0000-0003-3201-299X
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About
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Research Areas
  • HIV/AIDS Research and Interventions
  • HIV Research and Treatment
  • HIV, Drug Use, Sexual Risk
  • HIV-related health complications and treatments
  • HIV/AIDS drug development and treatment
  • Noise Effects and Management
  • Hearing, Cochlea, Tinnitus, Genetics
  • Adolescent Sexual and Reproductive Health
  • Hearing Loss and Rehabilitation
  • Effects and risks of endocrine disrupting chemicals
  • Anesthesia and Neurotoxicity Research
  • Cystic Fibrosis Research Advances
  • Childhood Cancer Survivors' Quality of Life
  • Lipid metabolism and disorders
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Sex work and related issues
  • Hepatitis B Virus Studies
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Genetics and Neurodevelopmental Disorders
  • Lipoproteins and Cardiovascular Health
  • Folate and B Vitamins Research
  • HIV, TB, and STIs Epidemiology

Nanjing Municipal Center for Disease Control And Prevention
2017-2025

Changsha Medical University
2021

<sec> <title>BACKGROUND</title> Due to compromised immune systems, people living with HIV/AIDS (PLWHA) are at an increased risk of opportunistic infections and deaths. </sec> <title>OBJECTIVE</title> The aim this study was develop spatial externally validate a predictive model for the survival PLWHA following initiation highly active anti-retroviral therapy (HAART) in China. <title>METHODS</title> This retrospective cohort used data from epidemic surveillance system National Center AIDS/STD...

10.2196/preprints.71257 preprint EN cc-by 2025-01-14

To analyze the transmission characteristics of newly reported HIV-infected students aged ≥18 years in Nanjing City from 2016 to 2022 and provide evidence for AIDS publicity intervention among young students. The pol region sequences non-student individuals were collected, BLAST tool was used search published global non-Nanjing HIV infection LANL database. basic molecular network regional constructed using HIV-TRACE a pairwise genetic distance threshold 1.0%. 332 infected aged≥18 City, 1 904...

10.3760/cma.j.cn112150-20240506-00362 article EN PubMed 2025-01-06

Objective This study aimed to investigate the epidemiological characteristics and HIV/AIDS-related knowledge, attitudes practice (KAP) among HIV-positive college students. Design A cross-sectional study. Setting Five districts of Nanjing, China. Participants total 156 students with newly diagnosed HIV infection between September 2015 July 2017. Main outcome measures Social-demographic characteristics, mode acquisition, sexually transmitted diseases, risky sexual behaviours KAP were collected...

10.1136/bmjopen-2019-035889 article EN cc-by-nc BMJ Open 2020-05-01

Abstract Objective The objective of this study was to conduct a comprehensive analysis the molecular transmission networks and transmitted drug resistance (TDR) patterns among individuals newly diagnosed with HIV-1 in Nanjing. Methods Plasma samples were collected from HIV patients Nanjing between 2019 2021. pol gene amplified, resulting sequences utilized for determining TDR, identifying viral subtypes, constructing network. Logistic regression analyses employed investigate epidemiological...

10.1186/s12879-024-09337-6 article EN cc-by BMC Infectious Diseases 2024-06-12

Objective To examine the trends of HIV prevalence, risk behaviours and testing among men who have sex with (MSM) in Nanjing. Design Five consecutive cross-sectional surveys. Setting Nanjing, China. Primary secondary outcome measures syphilis rate factors associated infection; demographic characteristics behaviours. Results 649, 669, 577, 633, 503 MSM were recruited from 2013 to 2017. prevalence was 9.9%, 12.3%, 12.5%, 9.8% 10.1%, respectively. Syphilis decreased a range 10.6% 5.6%. Risk like...

10.1136/bmjopen-2018-021955 article EN cc-by-nc BMJ Open 2019-01-01

Background Although the introduction of antiretroviral therapy (ART) decreased mortality people living with Human Immunodeficiency Virus (PLHIV), substantially, hundreds thousands are dying AIDS each year. The accurate survival patterns and factors related to death among PLHIV were rarely reported. In this study, we evaluated status identified associated in Nanjing. Methods We conducted a retrospective analysis followed-up Nanjing registered national HIV/AIDS comprehensive management...

10.3389/fpubh.2022.989127 article EN cc-by Frontiers in Public Health 2022-10-19

Great achievements have been achieved by free antiretroviral therapy (ART). A rapid and accurate prediction of survival in people living with HIV/AIDS (PLHIV) is needed for effective management. We aimed to establish an prognostic model forecast the PLHIV after ART.The participants were enrolled from a follow-up cohort over 2003-2019 Nanjing AIDS Prevention Control Information System. nested case-control study was employed HIV-related death, propensity-score matching (PSM) approach applied...

10.1186/s12889-021-12249-8 article EN cc-by BMC Public Health 2022-01-06

The growing HIV epidemic among student men who have sex with (MSM) necessitates immediate attention from public health. In China, male students (SMSM) were also at an increasing risk of transmission. aim this study was to investigate the trends in prevalence, HIV-related behaviors, and testing, as well analyze factors associated infection SMSM Nanjing.Data collected through face-to-face questionnaire interviews laboratory testing Nanjing. participants recruited by snowball sampling...

10.3389/fpubh.2022.806600 article EN cc-by Frontiers in Public Health 2022-04-27

College students are disproportionately affected by HIV-1 in China. However, little is known about the genetic characteristics of among this population. A molecular epidemiological investigation was conducted newly diagnosed antiretroviral therapy-naïve HIV-1-infected individuals during 2015–2019 Nanjing city, The pol fragment (HXB2: 2,253–3,311) obtained RNA extraction and gene amplification, subjected to genotyping, recombination analysis, phylogenetic inference. total 945 sequences from...

10.1089/aid.2019.0288 article EN AIDS Research and Human Retroviruses 2020-04-22

Objective: To investigate the situation of recreational drug nitrous acid ester inhaler-rush poppers use in men who have sex with (MSM). Methods: From April to June 2014, October December 2015, three round cross-sectional surveys were conducted MSM recruited Nanjing by means serum test and questionnaire survey. Results: Of 1 721 surveyed round, 19.3% (332/1 721) had ever used rush poppers, proportions showed an increasing trend (liner liner χ(2)= 14.879, P=0.000), which was 12.6% (86/681),...

10.3760/cma.j.issn.0254-6450.2017.02.011 article EN PubMed 2017-02-10

Objective: To understand the current status of HIV infection in men who have sex with (MSM) Nanjing, explore associated factors infection, and provide information for intervention MSM. Methods: Data collected consecutive sentinel surveillances among MSM during 2011-2015 includes MSM's social-demographic information, sexual behavior histories, access to prevention services testing past year. The trend was analyzed χ2 test were identified through multivariate logistic regression analysis....

10.3760/cma.j.issn.0254-6450.2016.11.014 article EN PubMed 2016-11-10

Description of the transmission characteristics among older adults is helpful for tailored interventions. Epidemiological investigation combined with phylogenetic analysis were performed to reveal potential linkage people in Nanjing. During 2018-2022, 188 pol sequences successfully amplified. Multiple genotypes identified, including CRF07_BC (55.3%), CRF01_AE (30.3%), CRF08_BC (8.0%), B (3.2%), CRF55_01B (1.1%), CRF67_01B (0.5%),CRF68_01B (0.5%), and unique recombinant forms (URF) (1.1%)....

10.22541/au.171583993.37465974/v1 preprint EN Authorea (Authorea) 2024-05-16

<title>Abstract</title> Objective The objective of this study was to conduct a comprehensive analysis the molecular transmission networks and transmitted drug resistance (TDR) patterns among individuals newly diagnosed with HIV-1 in Nanjing. Methods Plasma samples were collected from HIV patients Nanjing between 2019 2021. pol gene amplified, resulting sequences utilized for determining TDR, identifying viral genotypes, constructing networks. Logistic regression analyses employed investigate...

10.21203/rs.3.rs-3651419/v1 preprint EN cc-by Research Square (Research Square) 2023-12-19

Abstract Objective To describe the epidemiological characteristics of PLHIV, and to assess age spatial distribution HIV prevalence over last decade in Nanjing. Methods We downloaded information reported PLHIV from Chinese HIV/AIDS comprehensive prevention system, we performed descriptive, one-way ANOVA, autocorrelation analysis, scanning mapping distribution. Results 5269 that fulfilled inclusion exclusion criteria were included our study. The for each year rose 1.09/10000 2011 5.70/10000...

10.21203/rs.3.rs-1440301/v1 preprint EN cc-by Research Square (Research Square) 2022-04-01

Abstract Background Although great achievements have been made since free antiviral treatment (ART) was available, an in-time and accurate prediction of survival for people living with HIV (PLHIV) is still needed effective management. We aimed to establish prognostic model forecast the probability PLHIV after ART. Methods The participants enrolled were from a follow-up cohort between 2003 2019 in Nanjing AIDS Prevention Control Information System. nested case-control study employed...

10.21203/rs.3.rs-197435/v1 preprint EN cc-by Research Square (Research Square) 2021-03-03
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