A5014322977- High-Temperature Coating Behaviors
- Subcritical and Supercritical Water Processes
- High Entropy Alloys Studies
- Hydrocarbon exploration and reservoir analysis
- Mosquito-borne diseases and control
- Higher Education and Teaching Methods
- Acute Ischemic Stroke Management
- Viral Infections and Vectors
- Retinopathy of Prematurity Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Aquaculture Nutrition and Growth
- Infant Development and Preterm Care
- RNA Interference and Gene Delivery
- TGF-β signaling in diseases
- GDF15 and Related Biomarkers
- MicroRNA in disease regulation
- Neonatal Respiratory Health Research
- Plant Disease Resistance and Genetics
- Viral Infectious Diseases and Gene Expression in Insects
- Job Satisfaction and Organizational Behavior
- Advanced Computational Techniques and Applications
- Cardiac Fibrosis and Remodeling
- Network Packet Processing and Optimization
- Video Surveillance and Tracking Methods
- Insect symbiosis and bacterial influences
Affiliated Hospital of Jining Medical University
2023-2025
Instituto Politécnico Nacional
2015-2024
Southern Medical University
2023-2024
Nanfang Hospital
2023-2024
Shihezi University
2023-2024
Inner Mongolia Medical University
2023
East China University of Technology
2020-2023
Suqian University
2023
Nanchang University
2022-2023
Zhengzhou University of Aeronautics
2023
Loss of miR-29 is associated with cardiac fibrosis. This study examined the role and therapeutic potential in mouse model hypertension induced by angiotensin II (AngII). By using microRNA microarray, situ hybridization, real-time polymerase chain reaction, we found that AngII-induced fibrosis hypertensive heart cultured fibroblasts were downregulation miR-29a-c via a Smad3-dependent mechanism. In vitro knockdown miR-29b enhanced but overexpression inhibited fibrosis, revealing protective...
Smad7 is an inhibitory Smad and plays a protective role in obstructive diabetic kidney disease. However, the mechanisms of hypertensive nephropathy remains unexplored. Thus, aim this study was to investigate regulatory ANG II-induced nephropathy. gene knockout (KO) wild-type (WT) mice received subcutaneous infusion II or control saline for 4 weeks via osmotic mini-pumps. produced equivalent hypertension KO WT mice; however, exhibited more severe renal functional injury as shown by increased...
Abstract The oxidation behavior of 316L stainless steel exposed at 400, 600 and 800 °C air for 100, 500 1000 h was investigated using different characterization techniques. Weight gain obeys a parabolic law, but the degree deviation n index is increasingly larger with increase temperature. A double oxide film, including Cr 2 O 3 Fe particles in outer FeCr 4 oxides inner, observed 400 °C. As regards to samples °C, critical exposure period around 100 exists process, which compact film...
Smad7 plays a negative regulatory role in many inflammatory diseases, but its effect on hypertensive disease remains unknown. The present study tested the hypothesis that overexpression of may have therapeutic potential for angiotensin II (Ang II)-mediated cardiac remodelling. Hypertensive heart was induced mice by subcutaneous infusion Ang 28 days and treated with non-invasive ultrasound-microbubble-mediated inducible gene transfer. We found largely reduced protected against fall left...
The Taiwan Cancer Registry (TCR) is a nationwide population-based registry that collects the data of patients with newly diagnosed cancer from hospitals ≥50 beds. TCR are high quality in terms completeness and timeliness. However, accuracy also crucial indicator. This study evaluated rates selected 55 major items long-form between 2014 2016 700 reported cases randomly 25 long-form-reporting hospitals. We calculated by employing reabstracted chart review. Among items, 38 (69%) were at least...
Abstract Introduction Our study investigated the association between hematocrit in first two hours (HCT2h) of life and retinopathy prematurity (ROP). Methods Data were obtained from an observational DRYAD database. The was conducted at Santa Clara Valley Medical Center (SCVMC). on preterm babies whose gestational age (GA) < 34 weeks collected prospectively January 2008 to February 2014. Logistic regression applied explore HCT2h ROP. Results A total 326 very infants born or earlier than...
Transforming growth factor β (TGF-β)/Smad3 signaling plays a central role in chronic heart disease. Here, we report that targeting Smad3 with inhibitor SIS3 an established mouse model of hypertension significantly improved cardiac dysfunctions by preserving the left ventricle (LV) ejection fraction (LVEF) and LV fractional shortening (LVFS), while reducing mass. In addition, treatment also halted progression myocardial fibrosis blocking α-smooth muscle actin-positive (α-SMA+) myofibroblasts...
Abstract Background Distant hybridization can result genome duplication and allopolyploid formation which may play a significant role in the origin evolution of many plant species. It is unclear how two or more divergent genomes coordinate one nucleus with single parental cytoplasm within allopolyploids. We used cytological molecular methods to investigate genetic epigenetic instabilities associated process distant formation, measuring changes chromosome number DNA methylation across...
Abstract Background RNA interference (RNAi) has been used as a promising approach to inhibit human immunodeficiency virus type 1 (HIV-1) replication for both in vitro and vivo animal models. However, HIV-1 escape mutants after RNAi treatment have reported. Expressing multiple small interfering RNAs (siRNAs) against conserved viral sequences can serve genetic barrier escape, optimization of the efficiency this process was aim study. Results An artificial polycistronic transcript driven by CMV...
Abstract We tested 294 domestic pet dogs in Mexico for neutralizing antibodies mosquito-borne flaviviruses. found high (42.6%) exposure to West Nile virus Reynosa (northern Mexico) and low (1.2%) Tuxtla Gutierrez (southern but very limited Aedes-borne Domestic may be useful sentinels virus.
Recombinant baculoviruses could be used as biological insecticides through the introduction and expression of exogenous genes (such those coding for proteins) that interfere with metabolism, metamorphosis (toxins, hormones, enzymes), immune system insects. The CrV1 secreted protein Cotesia rubecula polydnavirus (PDV) is responsible actin depolymerisation in haemocytes abolishment functions such phagocytosis cell spreading, thus allowing successful embryonic development parasitoid wasp. cDNA...
To study how hydrogen-rich saline (HS) promotes the recovery of testicular biological function in a hemi-sectioned spinal cord injury (hSCI) rat model, right hemisection was performed at T11-T12 Wistar rats. Animals were divided into four groups: normal group; vehicle group: sham-operated rats administered saline; hSCI subjected to and HRST HS. Hind limb neurological function, testis index, morphology, mean seminiferous tubular diameter (MSTD) epithelial thickness (MSET), expression heme...