Zhenzhen Zhu

ORCID: 0000-0003-3245-3306
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About
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Research Areas
  • Allergic Rhinitis and Sensitization
  • Asthma and respiratory diseases
  • Sinusitis and nasal conditions
  • Food Allergy and Anaphylaxis Research
  • Oral and Maxillofacial Pathology
  • Head and Neck Surgical Oncology
  • Metastasis and carcinoma case studies
  • Air Quality and Health Impacts
  • Peptidase Inhibition and Analysis
  • Lung Cancer Diagnosis and Treatment
  • Cancer Diagnosis and Treatment
  • Odor and Emission Control Technologies
  • Diabetes Treatment and Management
  • Lipoproteins and Cardiovascular Health
  • Metabolism and Genetic Disorders
  • Ocular Oncology and Treatments
  • Oral and gingival health research
  • Ectopic Pregnancy Diagnosis and Management
  • Teratomas and Epidermoid Cysts
  • Delphi Technique in Research
  • Vestibular and auditory disorders
  • Diet and metabolism studies
  • Pesticide Exposure and Toxicity
  • Infectious Diseases and Mycology
  • Cancer-related Molecular Pathways

Chinese Academy of Medical Sciences & Peking Union Medical College
1996-2024

Peking Union Medical College Hospital
1996-2024

Academy of Medical Sciences
1996-2023

Academia Sinica
2023

Gansu Provincial Hospital
2021

Wenzhou City People's Hospital
2020

Sichuan University
2013

West China Hospital of Sichuan University
2013

Shandong University
2010

Traditionally, it was believed that chronic rhinosinusitis with nasal polyps (CRSwNP) demonstrated less eosinophilic and more neutrophilic inflammation in China compared to North America Europe. However, inflammatory patterns may change over time. The study aimed analyze the changing trends clinical histological characteristics of CRSwNP time China.A total 115 consecutive patients from 2003 2005 114 2014 2016 were enrolled this retrospective study. data between 2 periods.The percentage...

10.1002/alr.22234 article EN International Forum of Allergy & Rhinology 2018-11-29

Sinonasal mucosal melanoma (SNMM) is a relatively rare malignant tumour with poor prognosis. This study was designed to identify prognostic factors and establish nomogram model predict the overall survival (OS) of patients SNMM.

10.1186/s12885-024-11888-5 article EN cc-by BMC Cancer 2024-02-07

Inflammatory myofibroblastic tumor (IMT), as a mesenchymal tumor, is common in the lung and abdomen but rare paranasal sinus nasopharynx.This study aimed to summarize clinical characteristics of IMT nasopharynx analyze relationship between treatment overall survival (OS).The features, treatment, follow-up data patients diagnosed with or from 2006 2017 were retrospectively analyzed, previous literature was reviewed.IMT often presents an ill-defined soft-tissue mass bone destruction invasion...

10.1155/2018/7928241 article EN cc-by BioMed Research International 2018-10-15

Objective To investigate the clinical characteristics and surgical outcomes of sinonasal tumors associated with tumor‐induced osteomalacia (TIO). Study Design Retrospective case series. Setting Single tertiary center. Methods We studied 43 patients (22 male, 21 female) who had lesions in nasal cavity paranasal sinus TIO underwent surgery between August 2006 November 2019. Results The mean ± SD duration onset symptoms was 3.9 2.6 years. most common tumor site ethmoid (76.7%), skull base...

10.1177/0194599820975432 article EN Otolaryngology 2020-12-08

Background: The pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) and mechanisms underlying different responses to systemic glucocorticoids (GC) remain unclear. major aim this study was explore the transcriptomic oxidative lipidomic signatures effects GC in patients clinical responses. Methods: Nasal polyp biopsies were obtained before after 14-day oral treatment from 16 CRSwNP, normal mucosa specimens collected 12 control subjects. RNA sequencing lipidomics performed,...

10.3389/fphar.2021.814953 article EN cc-by Frontiers in Pharmacology 2022-01-13

Nodular fasciitis (NF) is a benign, self-limiting, reactive soft tissue tumor that composed of fibroblasts and myofibroblasts often misdiagnosed as malignant lesion. reported in adults but rarely seen children. We report the case 3-year-old girl with rapidly growing NF left nasal cavity. The initial biopsy suggested possibility spindle cell or low-grade tumor, respectively. child underwent complete excision tumor. With help immunohistochemistry pathological consultation, final diagnosis was...

10.1177/0145561320932332 article EN cc-by-nc Ear Nose & Throat Journal 2020-06-24

Neoplasms in the infratemporal fossa (ITF) are rare and insidious lesions that cause various symptoms due to involvement of temporomandibular joint (TMJ), paranasal sinuses, orbit. Here, we report a case metastatic non-small cell lung adenocarcinoma ITF. The patient presented with facial pain limited mouth opening, which did not respond treatment for TMJ disorder, neoplasm was discovered ITF through medical imaging. With an open biopsy, diagnosis finalized. This suggested physician should...

10.1177/01455613231218139 article EN cc-by-nc Ear Nose & Throat Journal 2024-01-28

Eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) exhibits a poorer prognosis than noneCRSwNP. The aim of this study was to analyze the potential total immunoglobulin E (tIgE) and specific IgE (sIgE) levels in tissues for distinguishing assessing eCRSwNP.We enrolled 10 control 88 CRSwNP patients. clinical data patients were collected before surgery. Nasal mucosa taken during surgery measurements tIgE, sIgE (weed pollen, epidermal animal protein, mold, house dust, tree pollen),...

10.1159/000522624 article EN cc-by-nc International Archives of Allergy and Immunology 2022-01-01

Objective To investigate the clinical effect of hysteroscopic scar excision for cesarean pregnancy(CSP) and its on serum β-human chorionic gonadotropin(β-HCG). Methods From January 2017 to 2019, 83 patients with endogenous CSP admitted People's Hospital Wenzhou were divided into observation group(43 cases) control group(40 according different surgical methods.The group underwent lesion resection, while uterine artery embolization.The success rate, intraoperative bleeding volume,...

10.3760/cma.j.issn.1008-6706.2020.06.002 article EN 2020-03-15

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)

10.1530/endoabs.73.oc7.6 article EN Endocrine Abstracts 2021-05-15
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