Nevin Alayvaz Aslan

ORCID: 0000-0003-3292-8519
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About
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Research Areas
  • Lymphoma Diagnosis and Treatment
  • Trace Elements in Health
  • Multiple Myeloma Research and Treatments
  • Chronic Lymphocytic Leukemia Research
  • Iron Metabolism and Disorders
  • CNS Lymphoma Diagnosis and Treatment
  • Central Venous Catheters and Hemodialysis
  • Acute Lymphoblastic Leukemia research
  • Acute Myeloid Leukemia Research
  • Viral-associated cancers and disorders
  • Hemoglobinopathies and Related Disorders
  • TGF-β signaling in diseases
  • Diagnosis and Treatment of Venous Diseases
  • Oral Health Pathology and Treatment
  • Vascular Malformations and Hemangiomas
  • Retinal and Optic Conditions
  • Cancer Immunotherapy and Biomarkers
  • Protein Degradation and Inhibitors
  • Advanced Breast Cancer Therapies
  • Oral and gingival health research
  • Congenital Diaphragmatic Hernia Studies
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Antifungal resistance and susceptibility
  • Urologic and reproductive health conditions
  • Platelet Disorders and Treatments

Pamukkale University
2021-2024

Ondokuz Mayıs University
2015-2021

Izmir Atatürk Eğitim ve Araştırma Hastanesi
2012

Ankara Atatürk Eğitim ve Araştırma Hastanesi
2012

Izmir Tepecik Eğitim ve Araştırma Hastanesi
2012

Objective:The aim of the present study was to evaluate efficacy and safety eltrombopag, an oral thrombopoietin receptor agonist, in patients with chronic immune thrombocytopenia (ITP). Materials Methods:A total 285 ITP (187 women, 65.6%; 98 men, 34.4%) followed 55 centers were enrolled this retrospective cohort.Response treatment assessed according platelet count (/mm 3 ) defined as complete (platelet >100,000/mm ), partial (30,000-100,000/mm or doubling after treatment), unresponsive...

10.4274/tjh.galenos.2019.2018.0307 article TR Turkish Journal of Hematology 2019-07-22

The discovery of tyrosine kinase inhibitors provided a breakthrough in the treatment chronic myeloid leukemia. Nowadays, management inhibitor-related side effects is one important problems leukemia treatment. Grades 3-4 pulmonary toxicity; especially pleural effusion mostly seen with dasatinib but rarely nilotinib and bosutinib. Development cross-intolerance due to not an expected situation. Pleural related exudative nature abundant lymphocytes.Massive developed 59-year-old male patient...

10.1177/10781552221114070 article EN Journal of Oncology Pharmacy Practice 2022-07-12

Chronic antigenic stimulation is frequently blamed in the pathogenesis of extranodal marginal zone lymphomas including splenic lymphoma (SMZL). hepatitis C observed SMZL patients some geographical regions. However, these reports are largely from North America and Europe, data other countries insufficient. In this multicenter study we aimed to identify clinical characteristics Turkey, viral status treatment details.Data were gathered participating centers different regions Turkey using IBM...

10.4274/tjh.galenos.2019.2019.0177 article TR Turkish Journal of Hematology 2019-10-21

Acute myeloid leukemia (AML) is a hematologic malignancy characterized by the proliferation of CD34 positive self-renewing malignant hematopoietic stem cells. Previous studies have shown that transforming growth factor beta (TGFβ) pathway plays role in AML pathogenesis, especially affecting microenvironment. Growth differentiation 11 (GDF11) member TGFβ superfamily, involved embryological development and known as rejuvenating factor. In this study, our aim was to determine serum GDF11 level...

10.1177/10815589241238218 article EN Journal of Investigative Medicine 2024-02-28

Objective: New medicines employed in recent years have resulted significant increases survival rates for Multiple Myeloma (MM). Daratumumab is utilized both first-line myeloma treatment and relapsed/refractory illness. Our study aims to assess the clinical features, response factors influencing patients who received daratumumab monotherapy or combination therapy at our center. 
 Patients Methods: 21 multiple were followed up hematology clinic Pamukkale University Faculty of Medicine...

10.31362/patd.1427969 article EN cc-by-nc Pamukkale Medical Journal 2024-04-01

Incidence of venous thromboembolism (VTE) is higher than the expected in patients with hematologic malignancies and duration hospitalization period increases risk thrombosis. The objective this study was to investigate incidence factors for thrombosis hospitalized malignancies.

10.14744/nci.2023.92332 article EN cc-by-nc Northern Clinics of Istanbul 2024-01-01

Iron deficiency and zinc are known to disturb cognitive functions especially in infants preschool children. Our purpose was evaluate the effect of iron on function (with Montreal Cognitive Assessment [MoCA] score) females. We designed a randomized controlled prospective study. 41 deficient female patients 40 healthy volunteers were involved The average MoCA score ± SD 24,63 4,3 (range 11–30) anemia (IDA), 27.43± 2.02 (23-30) volunteers. Zinc level 97.06 (40.8–146.8) mg/dl 257.5 (128.2–463.7)...

10.52142/omujecm.38.2.10 article EN Journal of Experimental and Clinical Medicine 2021-03-14

e18084 Background: Multiple myeloma (MM) is characterized by the neoplastic proliferation of plasma cells producing a monoclonal immunoglobulin. The staging illness at moment diagnosis determines both approach to patient and treatment strategy. D.Salmon ISS systems, which have been used for long time, don’t contain some important risk factors. In this context, comparison system R-ISS identified in 2014 with addition genetic classification made FISH serum LDH level main aim our study....

10.1200/jco.2015.33.15_suppl.e18084 article EN Journal of Clinical Oncology 2015-05-20

ABSTRACT Acute megakaryoblastic leukemia (AML-M7) is rarely seen in adult patients and usually present with cytopenias. Here we discuss diagnostic challenges pathologic features a patient AML-M7 who presented thrombocytosis diarrhea. A 63-year-old male persistent diarrhea lasting for 2 months, fatigue, thrombocytosis. The workup included stool analysis, endoscopy colonoscopy, imaging studies; however, these studies did not reveal any possible etiology. hematologic evaluation peripheral blood...

10.4103/ijpm.ijpm_233_22 article EN cc-by-nc-sa Indian Journal of Pathology and Microbiology 2023-04-14

Aim:In this paper we evaluated the relationship between number of removed lymph nodes and postoperative morbidity during lymphadecetomy in early stage endometrium cancer.Material Method: Seventy-two patients with diagnosis I-II cancer underwent radical hysterectomy + pelvic paraaortic lymphadenectomy Izmir Atatürk Training Research Hospital, Department Gynecology Obstetric, 01.04.2002-31.04.2009.The clinical pathologic findings, immediate operative records were reviewed.The mean follow-up...

10.5222/terh.2012.63325 article EN The Anatolian Journal of General Medical Research 2012-01-01

Amaç: Akut miyeloid lösemi (AML) indüksiyon ve kurtarma tedavileri ile uzamış derin nötropeni gelişmekte, bu dönemde ortaya çıkan enfeksiyonlar mortalitenin önemli bir nedenini oluşturmaktadır.Çalışmamızda merkezimizde yatırılarak tedavi edilen yeni tanı veya nüks AML tanılı hastalarda takipleri boyunca alınan kan, idrar balgam kültürlerinde üreme saptanmasına etkili faktörleri kültür pozitifliğinin hastalık

10.5578/llm.20229701 article TR LLM Dergi 2022-12-20
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