A5076821260- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Chronic Myeloid Leukemia Treatments
- Acute Myeloid Leukemia Research
- Blood groups and transfusion
- Eosinophilic Disorders and Syndromes
- Complement system in diseases
- Kruppel-like factors research
- Platelet Disorders and Treatments
- Viral-associated cancers and disorders
- Iron Metabolism and Disorders
- Renal Diseases and Glomerulopathies
- Acute Lymphoblastic Leukemia research
- Hemoglobinopathies and Related Disorders
- T-cell and Retrovirus Studies
- Multiple Myeloma Research and Treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Cutaneous lymphoproliferative disorders research
- Quinazolinone synthesis and applications
- Nutritional Studies and Diet
- Heparin-Induced Thrombocytopenia and Thrombosis
- Reconstructive Surgery and Microvascular Techniques
- Pharmacological Effects and Toxicity Studies
- Ultrasound in Clinical Applications
Pamukkale University
2018-2024
Kahramanmaraş Sütçü İmam University
2024
Ege University
2024
Sağlık Bilimleri Üniversitesi
2023
Eskişehir City Hospital
2022
Eskişehir Osmangazi University
2022
Denizli Devlet Hastanesi
2015-2019
Izmir Bozyaka Eğitim ve Araştırma Hastanesi
2013-2016
Ankara Onkoloji Eğitim ve Araştırma Hastanesi
2014
Objective: Multiple myeloma (MM) is a heterogeneous disease caused by genetic and environmental factors. The aim of this study to determine whether the diagnosis MM exhibits seasonal pattern. Materials Methods: Eighty patients new diagnosed with between January 2020 July 2024 were included in study. All data on gender, age time recorded retrospectively from files patients. Results: 34 (42.5%) them female 46 (57.5%) male. median was 63 years (41-81). month highest number diagnoses November, 9...
Objective: Chronic myeloproliferative neoplasms (CMPNs) that include polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) are Philadelphia-negative malignancies characterized by a clonal proliferation of one or several lineages.The aim this report was to determine the demographic features, disease characteristics, treatment strategies, survival rates patients with CMPNs in Turkey.Materials Methods: Across all Turkey, 9 centers were enrolled study.We...
The aim of the study was to evaluate effect Controlling Nutritional Status (CONUT) score on prognosis in patients with diffuse large B-cell lymphoma (DLBCL).The present a retrospective study. CONUT calculated based serum albumin, total cholesterol and lymphocyte levels. This included 266 patients, 131 (49.2%) were female 135 (50.8%) male. median follow-up period 51 months (range: 1–190).The age 64 years. cut off 1.5. There significant difference between high (≥ 2) or low (< scores terms...
Immune thrombocytopenia (ITP) is an immune-mediated disease characterized by transient or persistent decrease of the platelet count to less than 100x109/L. Although it included in a benign group, bleeding complications may be mortal. With better understanding pathophysiology disease, thrombopoietin receptor agonists, which came into use recent years, seem effective option treatment resistant cases. This study aimed retrospectively assess efficacy, long-term safety, and tolerability...
Due to the heterogeneous nature of Diffuse Large B-cell Lymphoma (DLBCL), mechanisms underlying tumor development and progression have not yet been fully elucidated.This study aimed compare characteristics plasma exosomes DLBCL patients healthy individuals evaluate exosomal interactions between cell lines normal B-cells.Exosome isolation was performed using an ultracentrifugation-based protocol from 20 with controls. The expression miRNAs exosome samples analyzed a miRNA microarray. presence...
Purpose: In this study; we sought to assess whether elevated vitamin B12 levels during the course of diagnosis might be a predictor acute leukemias.
 Materials and Method: The study was prepared by retrospectively evaluating anamnesis laboratory information 95 patients diagnosed with leukemia (AML or ALL). Those who had any conditions clearly known increase scanning their were not included in study.
 Results: total, it observed that serum level at time above normal reference range...
Nodular lymphocyte predominant Hodgkin's lymphoma (NLPHL) is a rare subtype of lymphoma. In this study, we aimed to investigate the clinical features and therapeutic outcomes patients with NLPHL who were diagnosed at different institutes in Turkey. We retrospectively reviewed records NLPHL. Adult after 2005 histological confirmation selected for study. Forty-three included Median age was 37.5 years (18-70) time diagnosis. About 60.5% as stage I II NLPHL, remaining 39.5% had III IV disease....
Amaç: Anjiyofolliküler lenf nodu hiperplazisi olarak da bilinen Castleman hastalığı (CH), nadir bir hastalık olup başlıca hiyalin vasküler ve plazma hücreli olmak üzere 2 histolojik alt tipi vardır.Hastalığın anatomik yayılımı tutulan bölgelerinin sayısına göre unisentrik (UCH) ya multisentrik (MCH) sınıflandırılır.Bu çok merkezli çalışmanın amacı bugüne kadar Türkiye'de tanımlanan tüm CH olgularını tanımlamak, ulusal veri tabanı oluşturarak CH'de erken tanı, tedavi takip sürecine katkı
Chronic antigenic stimulation is frequently blamed in the pathogenesis of extranodal marginal zone lymphomas including splenic lymphoma (SMZL). hepatitis C observed SMZL patients some geographical regions. However, these reports are largely from North America and Europe, data other countries insufficient. In this multicenter study we aimed to identify clinical characteristics Turkey, viral status treatment details.Data were gathered participating centers different regions Turkey using IBM...
Purpose: Chronic lymphocytic leukemia (CLL) is the most seen type of in adults. There are few biomarkes that used for better understanding how oxidative stress involved pathophysiology hematologic malignency.We aimed to stress, DNA damage and erythrocyte membrane lipid profile CLL patients this study. The study included 38 age-sex matched controls. Materials method: Total oxidant status (TOS), total antioxidant (TAS), index (OSI), examination with Comet assay, serum 8-OHdG measurement gas...
Recurrent episodes of venous thrombosis have been closely correlated with JAK2 V617F mutation. Upto date, gene mutation has not defined as a prothrombic risk factor in renal transplant recipients. Herein; we present case portosplenic vein primary recipient who had no history prior thromboembolism or thrombophilia. A 59 year old female caucasian patient kidney admitted vague abdominal pain at left upper quadrant. Abdominal doppler ultrasound and magnetic resonance imaging angiography...
Testicular myeloid sarcoma (TMS) is a challenging pathology often posing diagnostic difficulties due to the poorly differentiated nature of tumor cells at initial presentation. The delay in diagnosis significantly impacts patient life expectancy, emphasizing need for prompt identification and treatment initiation. In certain cases, presence Fms-like tyrosine kinase (FLT3) mutation adds complexity disease, requiring tailored therapeutic approaches. this report, we present unique case...
Aims: Acute myeloid leukemia (AML) is the most common type of in adults. Lung cancer one types cancer. The concomitant presentation AML and lung extremely rare. This study aimed to report a case series acute as metachronous or synchronous. Methods: We describe 6 cases with diagnosis these two diseases between years 2016-2020 our hospital. Patients treated hospital were retrospectively reviewed. Clinical characteristics, immunohistochemical genetic findings, treatments outcomes collected....
Introduction:Ruxolitinib is a small -molecule inhibitor of the JAK1/2 pathway.This study aimed to reveal results and side-effect profile use ruxolitinib as treatment option in polycythemia vera (PV).Methods: A total 34 patients with PV from 18 different centers were included study.The evaluation response under was determined reduction spleen volume (splenomegaly size: ≥35%) by imaging control hematocrit levels (≤45%) compared baseline.Results: While number which achieved 19 (55.9%) at 3...
Gaucher hastalığı, dalak karaciğer ve kemik iliğinde glukozilseramid birikimi ile karakterizedir. Hastalık otozomal resesif geçer lizozomal lipid depo hastalığıdır. Glukozilseramid hidrolaz (b-glukozidaz)'da genetik defekt sonucu retikuloendoteliyal sistem hücrelerinin lizozomlarda glukoseramid birikir. hastalığında masif splenomegali sitopeniler görülür. 37 yaşında hepatosplenomegali nedeniyle hastanemize başvuran erişkin yaşta hastalığı tanısı alan olgu sunuldu.