A5091796118- Chronic Lymphocytic Leukemia Research
- Antifungal resistance and susceptibility
- Lymphoma Diagnosis and Treatment
- Fungal Infections and Studies
- Acute Myeloid Leukemia Research
- Multiple Myeloma Research and Treatments
- Platelet Disorders and Treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- CNS Lymphoma Diagnosis and Treatment
- Neutropenia and Cancer Infections
- Chronic Myeloid Leukemia Treatments
- Complement system in diseases
- Blood groups and transfusion
- Acute Lymphoblastic Leukemia research
- Hematopoietic Stem Cell Transplantation
- Hematological disorders and diagnostics
- Viral-associated cancers and disorders
- Pneumocystis jirovecii pneumonia detection and treatment
- Eosinophilic Disorders and Syndromes
- Bone and Joint Diseases
- Protein Degradation and Inhibitors
- Peptidase Inhibition and Analysis
- Cancer Risks and Factors
- Kruppel-like factors research
- Sarcoma Diagnosis and Treatment
Bursa Uludağ Üni̇versi̇tesi̇
2016-2025
Creative Commons
2024
Sağlık Bilimleri Üniversitesi
2020-2022
Adli Tıp Kurumu
2021
Ufuk University
2020
Kocaeli Üniversitesi
2015
Ankara University
2007
Although bone marrow metastases can be found commonly in some malignant tumors, diagnosing a nonhematologic malignancy from is not usual event.To underscore the value of aspiration and biopsy as short cut establishing diagnosis for disseminated we reviewed 19 patients with malignancies who initially had marrow.The main indications examination were microangiopathic hemolytic anemia (MAHA), leukoerythroblastosis (LEB) unexplained cytopenias. Bone was diagnostic due to dry tap or inadequate...
Background: Although the cure rates of classical Hodgkin Lymphoma (cHL) are as high 90% using current treatment protocols, prognosis is poor for primary refractory patients. Thus, a biomarker that can predict patients with early progression at time diagnosis an unmet clinical need. Endothelial activation and stress index (EASIX) its variant modified EASIX (mEASIX) scoring system currently used prediction in hematologic malignancies. This study aimed to investigate prognostic value mEASIX...
Background Febrile neutropenic patients are at high risk for developing invasive fungal infection (IFI). Currently, two treatment strategies, empiric and preemptive, used in febrile with IFI. This study aimed to evaluate empirical preemptive strategies high-risk hematologic malignancies. Methods We retrospectively analyzed 402 attacks 281 hematological malignancies hospitalized a university hospital hematology clinic. Between June 2006 January 2009, 154 episodes of 104 who met the...
Aims: It was aimed at measuring the comorbidities of chronic myeloid leukemia (CML) patients time diagnosis with different comorbidity indices and evaluating their effects on disease prognosis. Methods: The were retrospectively screened calculated in three indices: ACE-27 Comorbidity Index, Age-adjusted Charlson Elixhauser Index. C-statistic used to evaluate ability discriminate mortality. relationship between scores overall survival (OS) evaluated Kaplan-Meier curve. Mortality risk analyzed...
Myelodysplastic syndrome (MDS) is a clonal hematopoietic stem cell disease. Supportive treatments, such as erythropoiesis-stimulating agents (ESAs), are commonly used in patients with low-risk MDS. This study aimed to retrospectively assess the impact of bone marrow Mothers against decapentaplegic homolog 7 (SMAD-7) and Transforming Growth Factor Beta 1 (TGF-β1) protein expression on prognosis response ESA treatment We analyzed diagnosed MDS at adult hematology department Bursa Uludağ...
Background/Objectives: Low bone mineral density (BMD) is common in hemophilia patients. Identifying high-risk patients for low BMD early essential to prevent complications and reduce morbidity. The parathyroid hormone (PTH)/calcium (Ca) ratio a cost-effective marker predicting BMD, highlighting the need routine screening intervention this population. Hemophilia hereditary bleeding disorder caused by deficiencies clotting factors VIII (hemophilia A) IX B). Patients with are at risk of (BMD)....
Background: Several thrombotic risk assessment models have been proposed for identifying patients with a high of thrombosis (the IMPEDE venous thromboembolism (VTE), SAVED, and PRISM scores) in multiple myeloma (MM). Recently, adding biomarker (D-dimer) the VTE score has shown that it can boost detection power IMPEDED VTE. However, data from studies comparing these MM are scarce. Even real-world arguing utility low- or middle-income countries like Türkiye lacking. Methods: We aimed to show...
Abstract The impact of inflammatory markers such as systemic immune-inflammation (SII) index and inflammation response (SIRI) on myelofibrosis (MF) prognosis was evaluated for the first time in this study. Data from 60 patients diagnosed with MF between March 2011 September 2022 were retrospectively analyzed. In addition to disease-related markers, SII SIRI evaluated. our study, overall median survival (OS) 64 months. OS significantly shorter older than 65 years, high ferritin lymphocyte...
Current treatment modalities can cure up to 70–80 % of patients with classical Hodgkin lymphoma. Approximately, 20–30 require further options. Brentuximab vedotin has been approved for the relapsed and refractory In present study, we report experience brentuximab as single agent in 58 or The objective response rate was 63.5 13 complete responders (26.5 %) among 49 evaluated at early phase (2–5 cycles). Upon prolongation (≥6 cycles), 37 achieved a final 32.4 21.6 10.8 partial response....
Abstract Myelodysplastic syndrome (MDS) is a heterogeneous spectrum of clonal hematopoietic disorders with varying degrees cytopenia and morphologic dysplasia. The hemoglobin, albumin, lymphocyte, platelet (HALP) score prognostic marker in several types malignant tumors. Prognostic value HALP remains unclear for MDS. To determine the baseline We retrospectively analyzed data from 130 newly diagnosed MDS patients evaluated classified under score. By receiver operating characteristic (ROC)...
Summary Disseminated infections caused by members of the Fusarium fujikuroi species complex ( FFSC ) occur regularly in immunocompromised patients. Here, we present first human case ‐ member andiyazi. Fever, respiratory symptoms and abnormal computerised tomography findings developed a 65‐year‐old man with acute myelogenous leukaemia who was under posaconazole prophylaxis during his remission–induction chemotherapy. During course infection, two consecutive blood galactomannan values were...
Technetium-99m 2-methoxyisobutylisonitrile (99mTc-MIBI) is a lipophilic agent that has been proposed as useful tracer for the detection of disease sites in patients with multiple myeloma (MM). We performed prospective study to determine potential 99mTc-MIBI imaging evaluation extent primary advanced stage MM, compared skeletal survey and bone scintigraphy. Twenty MM at initial diagnosis underwent whole-body imaging, together contemporaneous The findings were correlated results scan. All...