A5070733037- Chinese history and philosophy
- Asian Culture and Media Studies
- Shoulder Injury and Treatment
- Sports injuries and prevention
- Tendon Structure and Treatment
- Orthopaedic implants and arthroplasty
- Shoulder and Clavicle Injuries
- Orthopedic Infections and Treatments
- Osteoarthritis Treatment and Mechanisms
- Total Knee Arthroplasty Outcomes
- Cancer-related molecular mechanisms research
- Orthopedic Surgery and Rehabilitation
- Muscle Physiology and Disorders
- Foot and Ankle Surgery
- Circular RNAs in diseases
- Fibroblast Growth Factor Research
- Hip and Femur Fractures
- Cardiac, Anesthesia and Surgical Outcomes
- Bone and Joint Diseases
- Surgical Sutures and Adhesives
- Elbow and Forearm Trauma Treatment
- Wnt/β-catenin signaling in development and cancer
- Ginseng Biological Effects and Applications
- International Science and Diplomacy
- Language, Metaphor, and Cognition
Dalian Medical University
2015-2025
Chongqing Medical University
2009-2025
Second Affiliated Hospital of Chongqing Medical University
2015-2025
Harvard University
2015-2020
Boston Children's Hospital
2015-2020
State Key Laboratory of Pharmaceutical Biotechnology
2016
Nanjing University
2016
Hunan University
2013
Central South University
2005-2012
The Affiliated Yongchuan Hospital of Chongqing Medical University
2009
Abstract Skeletal muscle has remarkable regeneration capacity and regenerates in response to injury. Muscle largely relies on stem cells called satellite cells. Satellite normally remain quiescent, but injury or exercise they become activated proliferate, migrate, differentiate, fuse form multinucleate myofibers. Interestingly, the inflammatory process following activation of myogenic program are highly coordinated, with myeloid having a central role modulating cell regeneration. Here, we...
Objectives: Pneumonia is a common perioperative complication in geriatric patients with hip fractures. This study aimed to analyze demographic characteristics, mortality rates, postoperative outcomes, and comorbidities, identify risk factors for mortality, develop nomogram predicting the prognosis of these patients. Methods: Data on hospitalized arthroplasty fractures from 2020 2023 at three hospitals were retrospectively analyzed. Patients divided into P group (patients complicated...
Significance The arrangement of nuclei in myofibers, which are multinucleated skeletal muscle cells, is essential for their proper function. Abnormal nuclear positioning myofibers a common feature several diseases, including centronuclear myopathy and muscular dystrophy. Here, we show an isoform the CIP protein (sk-CIP) contributes to regulation by interacting with both LINC complex (Linker Nucleoskeleton Cytoskeleton) proteins microtubule-organizing center (MTOC). Through these...
Global inactivation of Trbp, a regulator miRNA pathways, resulted in developmental defects and postnatal lethality mice. Recently, we showed that cardiac-specific deletion Trbp caused heart failure. However, its functional role(s) skeletal muscle has not been characterized. Using conditional knockout model, generated mice lacking the muscle. Unexpectedly, specific mutant appear to be phenotypically normal under physiological conditions. these exhibited impaired regeneration increased...
Abstract Background Glucocorticoid-induced osteoporosis (GIOP) is the most common secondary osteoporosis. Patients with GIOP are susceptible to fractures and subsequent delayed bone union or nonunion. Thus, effective drugs targets need be explored. In this regard, present study aims reveal possible mechanism of anti-GIOP effect all-trans retinoic acid (ATRA). Methods Bone morphogenetic protein 9 (BMP9)-transfected mesenchymal stem cells (MSCs) were used as an in vitro osteogenic model deduce...
BACKGROUND:The incidence of osteoclast-like giant cell tumor the pancreas (OGTP) is very low, and relatively little OGTP clinical data available. The present study, therefore, sought to conduct a more comprehensive analysis characteristics prognosis OGTP. MATERIAL AND METHODS:A large population-based cohort was conducted using Surveillance, Epidemiology End Results (SEER) registry. We systematic assessment demographic these patients, in addition assessing available prognostic therapeutic...
Telangiectatic osteosarcoma (TOS) is a rare type of for which limited clinical data available. Furthermore, the characteristics and prognosis TOS remain unclear.A large population-based cohort analysis was conducted using Surveillance, Epidemiology End Results (SEER) registry. The conventional (COS) patients from 2000 to 2017 were collected. categorical variables assessed by Chi-squared tests. Kaplan-Meier curves log-rank (Mantel-Cox) tests used examine survival outcomes between groups. Cox...
Positron emission tomography/computed tomography (PET/CT) images have been used in the radiotherapy treatment planning, especially delineations of biological target volumes (BTVs) tumors. However, it is not possible to accurately and precisely discriminate between tumors adjacent normal tissues PET/CT if with a high PET standard uptake value (SUV) such as brain stem other that are close tumors, or sub-clinical tumor low SUV encompassed by also SUV. CT image has relatively poor soft tissue...
Massive irreparable rotator cuff tears (MIRCTs) are among the most challenging shoulder conditions to treat surgically. Supraspinatus tendon reconstruction (STR) is a recently introduced technique for MIRCTs based on fascia lata-muscle interface healing, which completely differs from classic bridging with lata-tendon healing. However, histological and biomechanical comparisons of fascia-muscle fascia-tendon interfaces have not been performed.
<title>Abstract</title> Background Osteoarthritis (OA) is characterized by the progressive degeneration of synovial joint, leading to irreversible damage articular cartilage and subchondral bone. While animal models have advanced our understanding OA, numerous unresolved issues still remain. The zebrafish, known for its transparent body, rapid developmental, impressive regenerative capabilities, offers substantial potential osteoarthritis research. This study seeks establish a new OA model...