A5102719514- Pancreatitis Pathology and Treatment
- Nonlinear Waves and Solitons
- Algebraic structures and combinatorial models
- Nonlinear Photonic Systems
- Liver Disease Diagnosis and Treatment
- 3D Printing in Biomedical Research
- Electrospun Nanofibers in Biomedical Applications
- RNA Research and Splicing
- Gut microbiota and health
- Tissue Engineering and Regenerative Medicine
- Pancreatic and Hepatic Oncology Research
- Epigenetics and DNA Methylation
- Numerical methods for differential equations
- Advanced Topics in Algebra
- Advanced biosensing and bioanalysis techniques
- Innovative Microfluidic and Catalytic Techniques Innovation
- Phagocytosis and Immune Regulation
- Probiotics and Fermented Foods
- Genomics and Chromatin Dynamics
- Biosensors and Analytical Detection
- Anomaly Detection Techniques and Applications
- Natural Language Processing Techniques
- Pediatric Hepatobiliary Diseases and Treatments
- Biomarkers in Disease Mechanisms
- Silk-based biomaterials and applications
Southeast University
2011-2025
State Key Laboratory of Digital Medical Engineering
2007-2025
Zhongda Hospital Southeast University
2025
Nanjing Medical University
2018-2024
Nanjing General Hospital of Nanjing Military Command
2012-2024
Capital Normal University
2004-2023
Nanjing University
2012-2023
Nanjing Drum Tower Hospital
2023
University of Electronic Science and Technology of China
2022
Second People Hospital of Hunan
2021-2022
Black phosphorus quantum dots (BPQDs) have been prepared by a high turbulent shear rate generated from household kitchen blender. A layer-by-layer disintegration mechanism of bulk BP crystals is suggested. As-synthesized BPQDs shown excellent humidity sensing and photothermal converting properties. Importantly, this work not only explores potential applications for the but also provides successful paradigm preparing QDs other layered materials.
One of the key steps in Neural Architecture Search (NAS) is to estimate performance candidate architectures. Existing methods either directly use validation or learn a predictor performance. However, these can be computationally expensive very inaccurate, which may severely affect search efficiency and Moreover, as it difficult annotate architectures with accurate on specific tasks, learning promising often non-trivial due lack labeled data. In this paper, we argue that not necessary...
Responsive hydrogel microfibers can realize multiple controllable changes in shapes or properties under the stimulation of surrounding environment, and are called as intelligent biomaterials. Recently, these responsive have been proved to possess significant biomedical values, remarkable progress has achieved engineering applications, including drug delivery, biosensors clinical therapy, etc. In this review, latest research application prospects summarized. We first introduce common...
Drug microcarriers are widely used in disease treatment, and microfluidics is well established the preparation of microcarrier particles. A proper design microfluidic platform toward scalable production drug can extend its application values wound healing, where large numbers required. Here, a step emulsification method for monodisperse droplets presented. The droplet size depends primarily on microchannel depth rather than flow rate, making system robust high-throughput hydrogel...
Recovery of circulating tumor cells (CTCs) from cancer patients by an efficient CTCs capture and release method can greatly increase their application in diagnostics treatment cancers. In this paper, we presented a folic acid (FA)-functionalized hybrid photonic barcode for CTCs. The barcodes were formed two nano-ordered parts, poly(ethylene glycol) diacrylate (PEGDA) inverse opal structure sustaining integrity methacrylated gelatin (GelMA) gel filler conjugating FA molecules to mediate cell...
Abstract Advanced artificial nerve conduits offer a promising alternative for injury repair. Current research focuses on improving the therapeutic effectiveness of by optimizing scaffold materials and functional components. In this study, novel poly(3,4‐ethylenedioxythiophene) (PEDOT)‐integrated fish swim bladder (FSB) is presented as conductive conduit with ordered topology electrical stimulation to promote regeneration. PEDOT nanomaterials adhesive peptides (IKVAV) are successfully...
Wound healing has been a continuous critical focus in clinical practice, posing the ongoing challenges and burdens to patients. Current attempts tend develop multi-drug loaded patches with spatial design. Herein, we present multifunctional microneedle patch that integrates different drugs into separated regions for wound treatment. The is composed of silk fibroin-methacryloyl (SilMA) as base, silver nanoparticles (AgNPs) gelatin methacryloyl (GelMA) tips vascular endothelial growth factor...
Glucocorticoids such as dexamethasone have shown promising therapeutic effects in conquering oral ulcers. Challenges this area are focused on enhancing the localized curative and responsive release. Herein, we presented a novel MXene-integrated hydrogel microneedle delivering to promote healing of ulceration. By loading MXene, microneedles enable NIR (Near Infrared)-responsive release inner for inflammation control tissue regeneration. In addition, MXene-induced local hyperthermia could...
Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling constitutes one the major pathways for cytokine signal transduction. However, role JAK2/STAT3 pathway in liver injury during severe acute pancreatitis (SAP) remains unclear. The aim this study was to investigate after SAP. In present 64 male Sprague-Dawley rats were randomly divided into four groups: Control, AG490 (inhibition JAK2), SAP with AG490. induced by retrograde infusion 4% sodium taurocholate...
Layer-by-layer self-assembly (LBL) technique is a very efficient and convenient method to modify the substrate surface. In this study, we report self-repairing surface coating that can promote cell adhesion, especially for enhancing adhesion of coral cells on basal The results confirmed modified chitosan-dialdehyde starch film based Schiff base has good biocompatibility common mammalian cells, such as normal human dermal fibroblasts (NHDFs) relatively special (coral cells). cytotoxicity test...
High-quality and comprehensive reference gene catalogs are essential for metagenomic research. The rather low diversity of samples used to construct existing the mouse gut metagenome limits numbers identified genes in catalogs. We therefore established an expanded catalog (EMGC) containing >5.8 million by integrating 88 newly sequenced samples, 86 gut-related bacterial genomes, 3 EMGC increases number nonredundant more than 1 compared so-far most extensive catalog. More 60% were assigned...
Background: Major depressive disorder (MDD) is a common disease which complicated by metabolic disorder. Although MDD has been studied relatively intensively, its metabolism yet to be elucidated. Methods: To profile the global pathophysiological processes of patients, we used metabolomics identify differential metabolites and applied new database Metabolite set enrichment analysis (MSEA) discover dysfunctions pathways this disease. Hydrophilic were profiling plasma from 55 patients 100 sex-,...
We construct the integrable deformations of Heisenberg supermagnet model with quadratic constraints (i) S2 = 3S − 2I, for S ∊ USPL(2/1)/S(U(2) × U(1)) and (ii) S, USPL(2/1)/S(L(1/1) U(1)). Under gauge transformation, their corresponding equivalent counterparts are derived. They Grassman odd super mixed derivative nonlinear Schrödinger equation, respectively.
The fermionic covariant prolongation structure theory is investigated. We extend the technique to multidimensional super nonlinear evolution equation and present fundamental equations determining structure. Furthermore, we investigate a (2+1)-dimensional Schrödinger analyze its integrability by means of this technique. derive Lax representation Bäcklund transformation. Moreover, solution integrable equation.
Aim: Pancreatic cancer (PC) is a devastating malignancy characterized by its aggressive nature and poor prognosis. However, the relationship of PC with peripheral metabolites remains not fully investigated. The study aimed to explore causal linkage between metabolite profiles. Methods: Employing publicly accessible genome-wide association studies (GWAS) data, we conducted bidirectional two-sample Mendelian randomization (MR) analysis. primary analysis employed inverse-variance weighted (IVW)...
We investigate some integrable modified Heisenberg ferromagnet models by using the prolongation structure theory. Through associating them with motion of curve in Minkowski space, corresponding coupled equations are presented.
Here we report a method for methylation analysis using rolling circle amplification (RCA) product microarray. We treated DNA samples with bisulfite and designed, each CpG region in the target gene, pair of padlock probes one matching to sites derived from methylated region, other TpG their corresponding unmethylated allele. The were hybridized PCR products bisulfite-treated genomic DNA, subsequently ligated form single-strand, circular template RCA reaction. immobilized on slide fabricate...