A5037440323- Acute Ischemic Stroke Management
- Nosocomial Infections in ICU
- Heart Rate Variability and Autonomic Control
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Chemotherapy-induced organ toxicity mitigation
- Mesenchymal stem cell research
- Neuroscience of respiration and sleep
- Liver Disease and Transplantation
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Cardiac Arrest and Resuscitation
- Clinical Nutrition and Gastroenterology
- Pneumocystis jirovecii pneumonia detection and treatment
- Hemodynamic Monitoring and Therapy
- Intracerebral and Subarachnoid Hemorrhage Research
- Diet and metabolism studies
- Renal function and acid-base balance
- Stroke Rehabilitation and Recovery
- Anesthesia and Sedative Agents
- Aortic aneurysm repair treatments
- Antibiotic Use and Resistance
- Epilepsy research and treatment
- Organ Transplantation Techniques and Outcomes
- Bladder and Urothelial Cancer Treatments
Ministry of Health
2025
Royal Stoke University Hospital
2025
University of Louisville
2015-2024
Tanta University
2015-2024
Inserm
1985-2024
Wayne State University
2024
Northwell Health
2024
Corewell Health
2024
Allama Iqbal Medical College
2024
Farwaniya Hospital
2024
Abstract: Inflammation is the body's response to insults, which include infection, trauma, and hypersensitivity. The inflammatory complex involves a variety of mechanisms defend against pathogens repair tissue. In lung, inflammation usually caused by or exposure toxins, pollutants, irritants, allergens. During inflammation, numerous types cells are activated. Each releases cytokines mediators modify activities other cells. Orchestration these molecules leads progression inflammation....
Delirium is characterized by a disturbance of consciousness with accompanying change in cognition. typically manifests as constellation symptoms an acute onset and fluctuating course. extremely common the intensive care unit (ICU) especially amongst mechanically ventilated patients. Three subtypes have been recognized: hyperactive, hypoactive, mixed. frequently undiagnosed unless specific diagnostic instruments are used. The CAM-ICU most widely studied validated instrument. However, accuracy...
It is unclear whether extracorporeal CO
Introduction: Critically ill patients placed on enteral nutrition (EN) are usually underfed. A volume‐based feeding (VBF) protocol designed to adjust the infusion rate make up for interruptions in delivery should provide a greater volume of EN than more common fixed hourly rate‐based (RBF) method. Methods: This single‐center, randomized (3:1; VBF/RBF) prospective study evaluated critically mechanical ventilation expected receive ≥3 days. Once goal was achieved, strategy implemented. In VBF...
Diabetic nephropathy is a clinical diagnosis where proteinuria present in patient with diabetes. Early intervention can significantly improve the prognosis. However, imprecision of currently available biomarkers have impaired effective therapies timely manner. Urinary N-acetyl-β-D-glucosaminidase (NAG) excreted abnormally high amounts many renal diseases. The aim this study was to evaluate urinary NAG as an early biomarker detection diabetic and whether it parallels severity kidney damage...
Acute kidney injury (AKI) is a complex clinical condition associated with significant morbidity and mortality lacking effective management. Ischemia-reperfusion (IRI) remains one of the leading causes AKI in native transplanted kidneys. The aim this study was to evaluate efficacy adipose-derived mesenchymal stem cells (ADSCs) prevention renal IRI rats. conducted on male Sprague-Dawley rats (n=72) weighing 250-300 g. Rats were randomly assigned three main groups: i) Sham-operated control...
Abstract Background The paracrine and regenerative activities of mesenchymal stem cells (MSCs) may vary with different cell sources. aim the present study is to compare effects MSCs from sources on acute kidney injury (AKI) induced by cisplatin their influence renal regeneration. Methods A single intraperitoneal injection (5 mg/kg) was used induce AKI in 120 Sprague-Dawley rats. Rats were treated either rat bone marrow (rBMSCs), human adipose tissue-derived (hADSCs), or amniotic...
BACKGROUND Upper respiratory tract infections (URTIs) are one of the most frequent causes childhood school leave and morbidity. AIM To study present trend medications’ prescribing pattern utilized in URTIs among pediatric population attending outpatient clinics hospitals. METHODS This analytical observational cross-sectional research was conducted 200 children aged 1–10 years with hospitals, which is an educational hospital, from July 2018 to August 2020. RESULTS Most prescriptions our...
Background and Purpose — The National Institutes of Health Stroke Scale (NIHSS) is predictive thrombus presence but has limited ability to identify occlusion location in the anterior circulation. We describe clinical sonographic patterns that are associated with tandem internal carotid artery (ICA) middle cerebral (MCA) occlusions. Methods Consecutive acute ischemic stroke patients receiving intravenous tissue plasminogen activator (TPA) were studied. Pretreatment NIHSS scores bedside...
Intravenous (i.v.) minocycline is increasingly used to treat infections caused by multidrug-resistant (MDR) Acinetobacter baumannii . Despite its being approved nearly 50 years ago, published information on pharmacokinetic (PK) profile limited. This multicenter study examined the PK and probability of pharmacokinetic-pharmacodynamic (PK-PD) target attainment i.v. in critically ill patients, with suspected or documented infection Gram-negative bacteria.
The inflammatory response is modulated through interactions among the nervous, endocrine, and immune systems. Intercommunication between cells autonomic nervous system a growing area of interest. Spatial temporal information about processes relayed to central (CNS) where neuroimmune modulation serves control extent intensity inflammation. Over past few decades, research has revealed various routes by which communicate. CNS regulates via hormonal neuronal pathways, including sympathetic...
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The effect of the intravenous (i.v.) shortacting anesthetic propofol on baroreflex control heart rate (HR) was examined in normotensive rats. Propofol infused at a fixed 9 mg/kg.h immediately after bolus dose 10 mg/kg. Blood pressure (BP) maintained with plasma substitute. Conscious rats were used for comparisons. Reflex HR responses recorded i.v. doses pressor agent phenylephrine and depressor sodium nitroprusside. Baroreceptor reflex parameters determined by sigmoidal computerized...
SUMMARY Flow cytometry and sorting proved to be a rapid method that facilitated the identification of different leukocyte populations in bovine blood milk. After briefly incubating whole milk samples hypotonic phosphate buffer, containing supravital acridine orange, 5 classes leukocytes were found (lymphocytes, neutrophils, eosinophils, basophils, monocytes) 4 monocytes, macrophages) by flow cytometry. Cells morphologically identified fluorescent microscopy after cytometric light...
Long-term evaluation of cisplatin induced nephrotoxicity and the probable renal protective activities stem cells are lacking up until now. We evaluated early long-term role human adipose derived mesenchymal (ADMSCs) in prevention or amelioration acute kidney injury (AKI) Sprague-Dawley rats. For this, we determined tissue level oxidative stress markers conjugation with a histopathological scoring system both chronic changes.This study used eighty (SD) rats weighing 250-300g. They were...