A5000997863- Cardiac Arrest and Resuscitation
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Mechanical Circulatory Support Devices
- Intensive Care Unit Cognitive Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Central Venous Catheters and Hemodialysis
- Hemodynamic Monitoring and Therapy
- Cardiac Imaging and Diagnostics
- Emergency and Acute Care Studies
- Trauma Management and Diagnosis
- Spinal Fractures and Fixation Techniques
- Pleural and Pulmonary Diseases
- Nosocomial Infections in ICU
- Dialysis and Renal Disease Management
- Venous Thromboembolism Diagnosis and Management
- Infective Endocarditis Diagnosis and Management
- Spine and Intervertebral Disc Pathology
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Disaster Response and Management
- Heart Failure Treatment and Management
- Thermal Regulation in Medicine
- Cardiac Arrhythmias and Treatments
- Poisoning and overdose treatments
Brigham and Women's Hospital
2016-2025
Harvard University
2015-2025
University of Maryland, Baltimore
2018
Loma Linda University
2018
University of Michigan
2018
Loma Linda University Medical Center
2018
Singapore General Hospital
2012
Temple University Hospital
2012
Hadassah Medical Center
2012
University of Pennsylvania
2010
Objectives Our primary objective was to compare the utility of Deyo-Charlson Comorbidity Index (DCCI) and Elixhauser-van Walraven (EVCI) predict mortality in intensive care unit (ICU) patients. Setting Observational study 2 tertiary academic centres located Boston, Massachusetts. Participants The cohort consisted 59 816 patients from admitted 12 ICUs between January 2007 December 2012. Primary secondary outcome For analysis, receiver operator characteristic curves were constructed for at 30,...
It is unclear whether extracorporeal CO
Abstract Objective To evaluate the impact of coronavirus disease 2019 (COVID‐19) on emergency medical services (EMS) use for time‐sensitive conditions. We examined EMS cardiac arrest, stroke, and other emergencies across Massachusetts during peak COVID‐19 pandemic, evaluating their relationship to statewide incidence a declaration. Methods A retrospective analysis all calls between February 15 May 15, 2020 same time period 2019. call volumes were compared before after March 10, date Results...
Introduction: Non-depolarizing agents such as rocuronium and vecuronium are frequently used in the emergency department (ED) to facilitate intubation but may lead delay neurologic examination intervention. Sugammadex is for reversal of neuromuscular blockade by non-depolarizing its role ED poorly defined. Methods: This was a multicenter cohort study using retrospective chart review. We reviewed all encounters from June 21, 2016–February 9, 2024 electronic health record Mass General Brigham,...
Objective Extracorporeal cardiopulmonary resuscitation (ECPR) involves the initiation of venoarterial extracorporeal membrane oxygenation (ECMO) in patients cardiac arrest. After implementation a city-wide ECPR initiative, we brought together emergency medical services (EMS) personnel and two hospital-based teams (emergency medicine ECMO) for high-fidelity situ simulation with focus on identifying systems challenges opportunities improvement. Methods We performed arrest requiring including...
Sepsis is a major risk factor for acute respiratory distress syndrome (ARDS). However, there remains paucity of literature examining factors ARDS in septic patients early their course. This study examined the role fluid administration and identified other within first 6 h hospital presentation associated with developing patients. was secondary analysis adult presenting to Emergency Department or being admitted high-risk elective surgery from multicenter observational cohort study, US...
Burkholderia cepacia complex is a group of potential nosocomial pathogens often linked to contaminated water. We report on cluster 8 B. infections in cardiothoracic intensive care unit patients, which were attributed extracorporeal membrane oxygenation (ECMO) water heaters.In December 2020, we identified an increase the at Brigham and Women's Hospital. sought commonalities, sequenced isolates, obtained environmental specimens, enacted mitigation measures.Whole-genome sequencing 13 clinical...
OBJECTIVES: To determine whether multisite versus single-site dual-lumen (SSDL) cannulation is associated with outcomes for COVID-19 patients requiring venovenous extracorporeal membrane oxygenation (VV-ECMO). DESIGN: Retrospective analysis of the Extracorporeal Life Support Organization Registry. Propensity score matching (2:1 vs SSDL) was used to control confounders. PATIENTS: The matched cohort included 2,628 (1,752 multisite, 876 from 170 centers. mean ( sd ) age in entire 48 (11) years,...
Background: In severe cases, the COVID-19 viral pathogen produces hypoxic respiratory failure unable to be adequately supported by mechanical ventilation. The role of extracorporeal membrane oxygenation (ECMO) remains unknown, with few publications date lacking detailed patient information or management algorithms all while reporting excessive mortality. Methods: Case report from a prospectively maintained institutional ECMO database for COVID-19. Results: We describe veno-venous (VV) in...
In 2010, the Massachusetts Legislature passed a comprehensive law that restricted off-road vehicle (ORV) use by children <14 years old and regulated ORV up to age of 18 years. We aimed examine impact 2010 on rates ORV-related injuries.A retrospective analysis was performed emergency department (ED) inpatient discharges between 2002 2013 as found in Center for Health Information Analysis database using external causes injury codes specific injuries. Yearly population-based were compared...
Background: The United States is currently facing 2 epidemics: sustained morbidity and mortality from substance use the more recent COVID-19 pandemic. We tested hypothesis that pandemic has disproportionately affected individuals with disorder by evaluating average daily 9-1-1 ambulance calls for use-related issues compared all other calls. Methods: This was a retrospective cross-sectional analysis of before after start in Massachusetts. used consecutive samples calls, categorized into those...
To assess the safety and feasibility of a new protocol for interhospital critical care transport mechanically ventilated patients in prone position during coronavirus disease 2019 pandemic by nurse paramedic teams.Retrospective observational study.Single agency serving multiple centers greater Boston area.All transports intubated with severe hypoxemic respiratory failure secondary to 2019.Records were reviewed transported position. Major adverse events transport, defined as hypoxemia (oxygen...
Background Neuromuscular blockade (NMB) agents are often administered to control shivering during targeted temperature management following cardiac arrest. In this study, we hypothesized that early, continuous NMB would result in a greater reduction serum lactate levels among comatose patients after Methods and Results Randomized trial of for 24 hours versus usual care arrest conducted at 5 urban centers the United States. Adult who achieved return spontaneous circulation, remained...
We sought to determine the outcome of suicidal hanging and impact targeted temperature management (TTM) on hanging-induced cardiac arrest (CA) through an Eastern Association for Surgery Trauma (EAST) multicenter retrospective study.We analyzed patient data TTM variables from January 1992 December 2015. Cerebral performance category score 1 or 2 was considered good neurologic outcome, while cerebral 3 4 poor outcome. Classification Regression Trees recursive partitioning used develop...
BACKGROUND: Emergency physicians frequently encounter patients with acute small bowel obstructions (SBO).Although computed tomography (CT) imaging is the current gold standard in assessment of suspected SBO emergency department, a few studies have examined use ultrasound as an alternative technique. METHODS:We evaluated accuracy performed ED by variety providers (physicians various levels training, physician assistants) compared to CT 47 SBOs. RESULTS:Our data demonstrated sensitivity 93.8%...