A5083937518- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Cardiac Arrest and Resuscitation
- Intensive Care Unit Cognitive Disorders
- Hemodynamic Monitoring and Therapy
- Family and Patient Care in Intensive Care Units
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Emergency and Acute Care Studies
- Airway Management and Intubation Techniques
- Blood transfusion and management
- Trauma and Emergency Care Studies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Palliative Care and End-of-Life Issues
- Patient Safety and Medication Errors
- Neonatal Respiratory Health Research
- COVID-19 Clinical Research Studies
- Healthcare Technology and Patient Monitoring
- Cardiac, Anesthesia and Surgical Outcomes
- Mechanical Circulatory Support Devices
- Pneumonia and Respiratory Infections
- Clinical Reasoning and Diagnostic Skills
- Electronic Health Records Systems
- Heart Failure Treatment and Management
- Nosocomial Infections in ICU
- Disaster Response and Management
Mayo Clinic in Arizona
2016-2025
Mayo Clinic
2016-2025
Mayo Clinic in Florida
2015-2025
WinnMed
2012-2024
Pulmonary and Critical Care Associates
2010-2024
SleepMed
2024
Mayo Clinic Health System
2024
Mayo Clinic Hospital
2023
Flinders Medical Centre
2022
Baylor College of Medicine
2021-2022
Section:ChooseTop of pageAbstract <<ContentsOverviewIntroductionMethodsRecommendations for Speci...ConclusionsReferencesCITING ARTICLES
Accurate, early identification of patients at risk for developing acute lung injury (ALI) provides the opportunity to test and implement secondary prevention strategies.To determine frequency outcome ALI development in validate a prediction score (LIPS).In this prospective multicenter observational cohort study, predisposing conditions modifiers predictive were identified from routine clinical data available during initial evaluation. The discrimination model was assessed with area under...
Acute lung injury (ALI) that develops 6 hours after transfusion (TRALI) is the leading cause of transfusion-related mortality. Several characteristics have been postulated as risk factors for TRALI, but evidence limited to retrospective studies.
Early goal-directed therapy (EGDT) consists of early, aggressive fluid resuscitation and is known to improve survival in sepsis. It unknown how often EGDT leads subsequent overload whether post-EGDT affects patients' outcomes. Our hypothesis was that patients with sepsis treated were at risk for would be associated adverse We conducted a retrospective cohort 405 consecutive admitted severe septic shock the medical intensive care unit tertiary academic hospital from January 2008 December...
significant progress has been made in understanding the pathogenesis of acute respiratory distress syndrome (ARDS). Recent advances hospital practice may have reduced incidence this lethal syndrome.to observe trends and associated outcomes ARDS.this population-based cohort study was conducted Olmsted County, Minnesota. Using a validated screening protocol, investigators identified intensive care patients with hypoxemia bilateral pulmonary infiltrates. The presence ARDS independently...
<h3>Importance</h3> Management of acute respiratory distress syndrome (ARDS) remains largely supportive. Whether early intervention can prevent development ARDS unclear. <h3>Objective</h3> To evaluate the efficacy and safety aspirin administration for prevention ARDS. <h3>Design, Setting, Participants</h3> A multicenter, double-blind, placebo-controlled, randomized clinical trial conducted at 16 US academic hospitals. Between January 2, 2012, November 17, 2014, 7673 patients risk (Lung...
Abstract Background Coronavirus disease 2019 (COVID-19) pandemic has caused unprecedented pressure on healthcare system globally. Lack of high-quality evidence the respiratory management COVID-19-related acute failure (C-ARF) resulted in wide variation clinical practice. Methods Using a Delphi process, an international panel 39 experts developed practice statements C-ARF areas where is absent or limited. Agreement was defined as achieved when > 70% voted for given option Likert scale...
Respiratory failure is a leading cause of postoperative morbidity and mortality in patients undergoing pneumonectomy. The authors hypothesized that intraoperative mechanical ventilation with large tidal volumes (VTs) would be associated increased risk postpneumonectomy respiratory failure.Patients elective pneumonectomy at the authors' institution from January 1999 to 2003 were studied. collected data on demographics, relevant comorbidities, neoadjuvant therapy, pulmonary function tests,...
Almost half of the patients with septic shock develop acute lung injury (ALI). The understanding why some do and others not ALI is limited. objective this study was to test hypothesis that delayed treatment associated development ALI.Observational cohort study.Medical intensive care unit in a tertiary medical center.Prospectively identified who did have at outset, excluding those denied research authorization.High frequency cardio-respiratory monitoring, arterial gas analysis, portable chest...
Abnormalities in gas exchange that occur during anesthesia are mostly caused by atelectasis, and these alterations more pronounced morbidly obese than normal weight subjects. Sustained lung insufflation is capable of recruiting the collapsed areas improving oxygenation healthy patients weight. We tested effect this ventilatory strategy on arterial (Pao2) undergoing laparoscopic bariatric surgery. After pneumoperitoneum was accomplished, recruitment group received up to 4 sustained inflations...
Objective: Although restrictive red cell transfusion practice has become a standard of care in the critically ill, data on use fresh frozen plasma (FFP) are limited. We hypothesized that FFP medical intensive unit is variable and liberal may not be associated with improved outcome. Design: Retrospective cohort study. Setting: A 24-bed tertiary referral center. Patients: All patients admitted to during 5-month period who had abnormal coagulation defined as international normalized ratio (INR)...
Abstract Introduction The role of non-invasive positive pressure ventilation (NIPPV) in the treatment acute lung injury (ALI) is controversial. We sought to assess outcome ALI that was initially treated with NIPPV and identify specific risk factors for failure. Methods In this observational cohort study at two intensive care units a tertiary center, we identified consecutive patients who were NIPPV. Data on demographics, APACHE III scores, degree hypoxemia, respiratory parameters recorded....
The care of critically ill patients generates large quantities data. Increasingly, these data are presented to the provider within an electronic medical record. manner in which organized and can impact on ability users synthesis that into meaningful information. objective this study was test hypothesis novel user interfaces, prioritize display high-value providers system-based packages, reduce task load, result fewer errors cognition compared with established interfaces do not.Randomized...
While acute lung injury (ALI) is among the most serious postoperative pulmonary complications, its incidence, risk factors and outcome have not been prospectively studied.To determine incidence survival of ALI associated respiratory failure association with intraoperative ventilator settings, specifically tidal volume.Prospective, nested, case control study.Single tertiary referral centre.4420 consecutive patients without undergoing high elective surgeries for complications.Incidence ALI,...
Objective: We evaluated the effect of two quality improvement interventions (low tidal volume ventilation and restrictive transfusion) on development acute lung injury in mechanically ventilated patients. Design: Observational cohort study. Setting: Three intensive care units a tertiary academic center. Patients: included patients who were for ≥48 hrs excluding those refused research authorization or had preexisting pneumonectomy. Interventions: Multifaceted interdisciplinary intervention...