A5056143246- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Pain Management
- Opioid Use Disorder Treatment
- Pain Management and Opioid Use
- Cannabis and Cannabinoid Research
- Hemodynamic Monitoring and Therapy
- Trauma and Emergency Care Studies
- Prenatal Substance Exposure Effects
- Musculoskeletal pain and rehabilitation
- Treatment of Major Depression
- Substance Abuse Treatment and Outcomes
- Cardiac Arrest and Resuscitation
- Respiratory Support and Mechanisms
- Frailty in Older Adults
- Anesthesia and Sedative Agents
- Airway Management and Intubation Techniques
- Emergency and Acute Care Studies
- Blood Pressure and Hypertension Studies
- Health Systems, Economic Evaluations, Quality of Life
- Innovative Human-Technology Interaction
- Electroconvulsive Therapy Studies
- Tactile and Sensory Interactions
- Interactive and Immersive Displays
- Enhanced Recovery After Surgery
- Pain Management and Placebo Effect
University of Toronto
2016-2025
University Health Network
2017-2025
Toronto Western Hospital
2025
Women's College Hospital
2025
St. Michael's Hospital
2019-2024
Toronto General Hospital
2015-2024
Unity Health Toronto
2022-2024
Public Health Ontario
2023-2024
Novem (Netherlands)
2019-2022
Centre for Addiction and Mental Health
2021
<b>Objective</b> To evaluate the effects of intraoperative protective ventilation on major postoperative respiratory complications and to define safe mechanical ventilator settings that do not translate into an increased risk complications. <b>Design</b> Hospital based registry study. <b>Setting</b> Academic tertiary care hospital two affiliated community hospitals in Massachusetts, United States. <b>Participants</b> 69 265 consecutively enrolled patients over age 18 who underwent a...
We describe the development, application and evaluation of a design method tailored for working with people mild to moderate dementia. Our experiences approach highlighted areas where designers participants held radically different views. The tenet our was that overcome these differences we needed create an empathic relationship between designers. To achieve this modified participatory techniques foster respectful engagement in development digital aid facilitate "safe walking". process...
Evaluate the dose-response relationship between intraoperative fluid administration and postoperative outcomes in a large cohort of surgical patients.Healthy humans may live state responsiveness without need for supplementation. Goal-directed protocols driven by such measures are limited their ability to define optimal during surgery.This analysis data on file included 92,094 adult patients undergoing noncardiac surgery with endotracheal intubation 2007 2014 at an academic tertiary care...
Duration of action increases with repeated administration neuromuscular-blocking agents, and intraoperative use high doses agent may affect respiratory safety.In a hospital-based registry study on 48,499 patients who received intermediate-acting the authors tested primary hypothesis that agents are dose dependently associated risk postoperative complications. In secondary analysis, evaluated association between neostigmine given for reversal Post hoc, effects appropriate (neostigmine ≤ 60...
<h3>Importance</h3> Small studies and anecdotal evidence suggest marked differences in the use of opioids after surgery internationally; however, this has not been evaluated systematically across populations receiving similar procedures different countries. <h3>Objective</h3> To determine whether there are frequency, amount, type dispensed among United States, Canada, Sweden. <h3>Design, Setting, Participants</h3> This cohort study included patients without previous opioid prescriptions aged...
Objectives Our primary objective was to compare the utility of Deyo-Charlson Comorbidity Index (DCCI) and Elixhauser-van Walraven (EVCI) predict mortality in intensive care unit (ICU) patients. Setting Observational study 2 tertiary academic centres located Boston, Massachusetts. Participants The cohort consisted 59 816 patients from admitted 12 ICUs between January 2007 December 2012. Primary secondary outcome For analysis, receiver operator characteristic curves were constructed for at 30,...
Abstract Background Practice guidelines for perioperative pain management recommend that multimodal analgesic therapy should be used all postsurgical patients. However, the proportion of patients who actually receive this evidence-based approach is unknown. The objective study was to describe hospital-level patterns in utilization analgesia. Methods Data were obtained from Premier Research Database. Patients undergoing below-knee amputation, open lobectomy, total knee arthroplasty, and...
Online and digital technologies support extend the action repertoires of localized social movements. In this paper we examine ways by which can "on-the-ground" activist communities in development After identifying some challenges deploying conventional voting consultation for activism, situated political local through design deployment a low-cost community prototype, PosterVote. We deploy PosterVote two case studies with organizations features that supported or hindered grassroots democratic...
Abstract Background Although cannabis is known to have cardiovascular and psychoactive effects, the implications of its use before surgery are currently unknown. The objective present study was determine whether patients with an active disorder elevated risk postoperative complications. Methods authors conducted a retrospective population-based cohort undergoing elective in United States using Nationwide Inpatient Sample from 2006 2015. A sample 4,186,622 inpatients 18 65 yr age presenting...
Objective: The aim of this study was to describe national trends and outcomes in-hospital postoperative opioid overdose (OD) identify predictors OD. Summary Background Data: In 2000, the Joint Commission recommended making pain 5th vital sign, increasing focus on control. However, benefits management must be weighed against potentially lethal risk Methods: This is a retrospective multi-institutional cohort patients undergoing 1 6 major elective inpatient operation from 2002 2011 using...
Background Late-life depression (LLD) is associated with a decline in physical activity. Typically this assessed by self-report questionnaires and, more recently, actigraphy. We sought to explore the utility of bespoke activity monitor characterize profiles LLD precisely. Method The was worn for 7 days 29 adults and 30 healthy controls. Subjects underwent neuropsychological assessment quality life (QoL) (36-item Short-Form Health Survey) activities daily living (ADL) scales (Instrumental...
ABSTRACT Background The perioperative period provides a critical window to address opioid use, particularly in patients with history of chronic pain and presurgical use. Toronto General Hospital Transitional Pain Service (TPS) was developed the issues use after surgery. Aims To provide program evaluation results from TPS at highlighting weaning rates management opioid-naïve opioid-experienced surgical patients. Methods Two hundred fifty-one high-risk were dichotomized preoperatively as naïve...
Objectives: In this study, we examined whether (1) positive end-expiratory pressure (PEEP) has a protective effect on the risk of major postoperative respiratory complications in cohort patients undergoing abdominal surgeries and craniotomies, (2) PEEP is differed by surgery type. Background: Protective mechanical ventilation with lower tidal volumes reduces compounded after surgery. However, data regarding use intraoperative conflicting. Methods: observational included 5915 5063 craniotomy...
Abstract Background Opioids play a crucial role in providing analgesia throughout the perioperative period; however, patients may become persistent users of these medications months after surgery. Epidurals have been posited to prevent development pain, but there are little data on effect epidurals opioid use. Methods This study was conducted using claims database large, nationwide commercial health insurer. Opioid-naive who underwent open abdominal surgery from January 2004 December 2013...
We thought that the rate of postoperative pulmonary complications might be higher after pressure-controlled ventilation than volume-controlled ventilation. analysed peri-operative data recorded for 109,360 adults, whose lungs were mechanically ventilated during surgery at three hospitals in Massachusetts, USA. used multivariable regression and propensity score matching. Postoperative more common ventilation, odds ratio (95%CI) 1.29 (1.21-1.37), p < 0.001. Tidal volumes driving pressures...
Saving energy in residential and commercial buildings is of great interest due to diminishing resources. Heating ventilation air conditioning systems, electric lighting are responsible for a significant share usage, which makes it desirable optimise their operations while maintaining user comfort. Such optimisation requires accurate occupancy estimations. In contrast current, often invasive or unreliable methods we present an approach estimation using wireless sensor network (WSN) that only...