- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Sepsis Diagnosis and Treatment
- Mechanical Circulatory Support Devices
- Intensive Care Unit Cognitive Disorders
- Healthcare Technology and Patient Monitoring
- Airway Management and Intubation Techniques
- COVID-19 Clinical Research Studies
- Non-Invasive Vital Sign Monitoring
- Anesthesia and Sedative Agents
- Renal function and acid-base balance
- Hormonal Regulation and Hypertension
- Long-Term Effects of COVID-19
- Neonatal Respiratory Health Research
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Electronic Health Records Systems
- Quality and Safety in Healthcare
- Nosocomial Infections in ICU
- Cardiac electrophysiology and arrhythmias
- Hemodynamic Monitoring and Therapy
- Trauma and Emergency Care Studies
- Cardiomyopathy and Myosin Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
Tufts University
2025
University of Iowa Health Care
2024
University of Iowa
2022-2023
Emory University
2014-2021
Emory University Hospital
2014-2021
Emory Healthcare
2020-2021
Georgia Clinical and Translational Science Alliance
2020-2021
Centers for Disease Control and Prevention
2021
Decatur Memorial Hospital
2021
Collaborative Research Group
2021
To relate morbidity and mortality risk to preoperative severity of illness in patients undergoing coronary artery bypass grafting.Retrospective analysis 5051 using univariate logistic regression identify factors associated with perioperative mortality. Prospective application models a subsequent 2-year validation cohort (n = 4069).Cleveland Clinic Foundation.All adult graft surgery between July 1, 1986, June 30, 1988 (reference group), 1988, 1990 (validation group).Mortality (myocardial...
This report characterizes a cohort of hospitalized adults with coronavirus disease 2019 (COVID-19) in Georgia which black patients were overrepresented and one four had no recognized risk factors for severe COVID-19.
To determine mortality rates among adults with critical illness from coronavirus disease 2019.Observational cohort study of patients admitted March 6, 2020, to April 17, 2020.Six 2019 designated ICUs at three hospitals within an academic health center network in Atlanta, Georgia, United States.Adults greater than or equal 18 years old confirmed severe acute respiratory syndrome-CoV-2 who were ICU during the period.None.Among 217 critically ill patients, for those required mechanical...
The first reported U.S. case of coronavirus disease 2019 (COVID-19) was detected in January 2020 (1).As June 15, 2020, approximately 2 million cases and 115,000 COVID-19-associated deaths have been the United States.*Reports patients hospitalized with SARS-CoV-2 infection (the virus that causes COVID-19) describe high proportions older, male, black persons (2-4).Similarly, when comparing catchment area populations or nonhospitalized COVID-19 patients, underlying conditions, including...
We conducted a prospective multi-institutional clinical study involving community hospitals and academic medical centers to more carefully define the value of computerized tomography (CT) chest with transbronchial needle aspiration (TBNA) in staging bronchogenic carcinoma (CA), assess predictors positive aspirate. Of 360 individuals determined have carcinoma, 50 81 (62%) small cell (SCC) 135 279 (48%) non-small (NSCC) had aspirates (p = 0.034). TBNA precluded additional thoracic surgery...
Increasing time to mechanical ventilation and high-flow nasal cannula use may be associated with mortality in coronavirus disease 2019. We examined the impact of intubation on clinical outcomes patients
Acute respiratory distress syndrome (ARDS) is a devastating condition with an estimated mortality exceeding 30%. There are data suggesting risk factors for ARDS development in high-risk populations, but few available lower incidence populations. Using risk-matched analysis and combination of clinical research sets, we determined the this general surgical population.We conducted review common adult procedures completed between June 1, 2004 May 31, 2009 using anesthesia information system....
Abstract Background: Acute respiratory distress syndrome (ARDS) remains a serious postoperative complication. Although ARDS prevention is priority, the inability to identify patients at risk for barrier progress. The authors tested and refined previously reported surgical lung injury prediction (SLIP) model in multicenter cohort of at-risk patients. Methods: This secondary analysis multicenter, prospective investigation evaluating high-risk undergoing surgery. Preoperative factors modifiers...
Summary We report preliminary data from a cohort of adults admitted to COVID-designated intensive care units March 6 through April 17, 2020 across an academic healthcare system. Among 217 critically ill patients, mortality for those who required mechanical ventilation was 29.7% (49/165), with 8.5% (14/165) patients still on the ventilator at time this report. Overall date in is 25.8% (56/217), and 40.1% (87/217) have survived hospital discharge. Despite multiple reports rates exceeding 50%...
It is unclear whether extracorporeal CO
Medicolegal, clinical, and reimbursement needs warrant complete accurate documentation. We sought to identify improve our compliance rate for the documentation of arterial catheterization in perioperative setting.We first reviewed 12 mo electronic anesthesia records establish a baseline catheter Residents Certified Registered Nurse Anesthetists were randomly assigned control group experimental group. When surgical incision end documented record keeper, reminder routine checked an invasive...
Medical device hacking is a red herring. But the flaws are real.
We present an interpretable machine learning algorithm called ‘eARDS’ for predicting ARDS in ICU population comprising COVID-19 patients, up to 12-hours before satisfying the Berlin clinical criteria. The analysis was conducted on data collected from Intensive care units (ICU) at Emory Healthcare, Atlanta, GA and University of Tennessee Health Science Center, Memphis, TN Cerner ® Facts Deidentified Database, a multi-site EMR database. participants consisted adults over 18 years age. Clinical...
Lung protective ventilation strategies utilizing lower tidal volumes per predicted body weight (PBW) and positive end-expiratory pressure (PEEP) have been suggested to be beneficial in a variety of surgical populations. Recent clinical studies used control groups ventilated with high without PEEP based on the assumption that this reflects current practice. We hypothesized changed over time, most anesthetics U.S. academic medical centers are currently performed volumes, receive...
Sepsis is an established global health priority with high mortality that can be curtailed through early recognition and intervention; as such, efforts to raise awareness are potentially impactful increasingly common. We sought characterize trends in the of sepsis by examining temporal, geographic, other changes search engine utilization for information-seeking online. Using time series analyses mixed descriptive methods, we retrospectively analyzed publicly available usage data reported...
Abstract Background Coronavirus disease (COVID-19) can cause severe illness and death. Predictors of poor outcome collected on hospital admission may inform clinical public health decisions. Methods We conducted a retrospective observational cohort investigation 297 adults admitted to 8 academic community hospitals in Georgia, United States, during March 2020. Using standardized medical record abstraction, we data predictors including demographics, underlying conditions, outpatient...
Hematopoietic stem cell transplantation (HCT) is potentially curative for numerous malignant and non-malignant diseases but can lead to lung injury due chemoradiation toxicity, infection, immune dysregulation. Bronchoalveolar lavage (BAL) the most commonly used procedure diagnostic sampling of invasive, cannot be performed in medically fragile patients, challenging perform serially. We previously showed that BAL transcriptomes representing pulmonary inflammation cellular phenotype post-HCT...
Articles cited counts are catalogued and help identify landmark papers. This study provides a citation classics of anesthesiology literature using the framework subspecialties to provide review well-developed areas research in anesthesiology.A comprehensive list most-cited articles anesthesia was compiled bibliometric database general search terms such as "anesthesia" well subspecialty-specific terms. Queries were reviewed for relevance practice, categorized by subspecialty, ranked according...