A5080864215- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Global Health Care Issues
- Energy and Environment Impacts
- Influenza Virus Research Studies
- Global Cancer Incidence and Screening
- Air Quality Monitoring and Forecasting
- Noise Effects and Management
- Colorectal Cancer Screening and Detection
- Urban Transport and Accessibility
- Health disparities and outcomes
- COVID-19 epidemiological studies
- Cancer Risks and Factors
- Respiratory viral infections research
- Statistical Methods and Inference
- Thermoregulation and physiological responses
- Insurance, Mortality, Demography, Risk Management
- SARS-CoV-2 and COVID-19 Research
- Cervical Cancer and HPV Research
- Urban Heat Island Mitigation
- Vehicle emissions and performance
- Statistical Methods and Bayesian Inference
- Respiratory Support and Mechanisms
- Traffic and Road Safety
- Underground infrastructure and sustainability
University of Hong Kong
2014-2024
Chinese University of Hong Kong
2003-2024
Queen Mary Hospital
2016-2024
Nanyang Technological University
2019-2021
The University of Queensland
2020
University of Birmingham
2016
Creative Commons
2016
HKU-Pasteur Research Pole
2015-2016
RTI International
2016
Fudan University
2013
Exposure to ambient fine particulate matter (PM2.5) is a major global health concern. Quantitative estimates of attributable mortality are based on disease-specific hazard ratio models that incorporate risk information from multiple PM2.5 sources (outdoor and indoor air pollution use solid fuels secondhand active smoking), requiring assumptions about equivalent exposure toxicity. We relax these contentious by constructing PM2.5-mortality function only cohort studies outdoor covers the range....
We present an analysis of the first 10 weeks severe acute respiratory syndrome (SARS) epidemic in Hong Kong. The to date has been characterized by two large clusters—initiated separate “super-spread” events (SSEs)—and ongoing community transmission. By fitting a stochastic model data on 1512 cases, including these clusters, we show that etiological agent SARS is moderately transmissible. Excluding SSEs, estimate 2.7 secondary infections were generated per case average at start epidemic, with...
As yet, no one has written a comprehensive epidemiologic account of severe acute respiratory syndrome (SARS) outbreak from an affected country.
Abstract Background: Few studies have assessed long-term effects of particulate matter (PM) with aerodynamic diameter < 2.5 μm (PM2.5) on mortality for causes cancer other than the lung; we multiple causes. In Hong Kong, most people live and work in urban or suburban areas high-rise buildings. This facilitates estimation PM2.5 exposure individuals, taking into account height residence above ground level assessment health sufficient statistical power. Methods: We recruited 66,820...
Mendelian randomization (MR) leverages genetic information to examine the causal relationship between phenotypes allowing for presence of unmeasured confounders. MR has been widely applied unresolved questions in epidemiology, making use summary statistics from genome-wide association studies on an increasing number human traits. However, understanding essential concepts is necessary appropriate application and interpretation MR. This review aims provide a non-technical overview demonstrate...
A limited number of studies on long-term effects particulate matter with aerodynamic diameter < 2.5 μm (PM2.5) health suggest it can be an important cause morbidity and mortality. In Asia where air quality is poor deteriorating, local data PM2.5 to support policy management are scarce. We assessed the mortality in a single Asian city. For 10-13 years, we followed up cohort 66,820 participants ≥ 65 years age who were enrolled interviewed all 18 Elderly Health Centres Department Health, Hong...
To examine temperature in relation to stroke mortality a multicity time series study China.We obtained data on daily and from 8 large cities China. We used quasi-Poisson generalized additive models distributed lag nonlinear estimate the accumulative effects of across multiple days, adjusting for long-term seasonal trends, day week, air pollution, relative humidity. applied Bayesian hierarchical model pool city-specific effect estimates.Both cold hot temperatures were associated with...
Background Depression is a prevalent mental disorder that undiagnosed and untreated in half of all cases. Wearable activity trackers collect fine-grained sensor data characterizing the behavior physiology users (ie, digital biomarkers), which could be used for timely, unobtrusive, scalable depression screening. Objective The aim this study was to examine predictive ability biomarkers, based on from consumer-grade wearables, detect risk working population. Methods This cross-sectional 290...
BackgroundPoverty is a major determinant of population health, but little known about its role in modifying air pollution effects.ObjectivesWe set out to examine whether people residing socially deprived communities are at higher mortality risk from ambient pollution.MethodsThis study included 209 tertiary planning units (TPUs), the smallest for town Special Administrative Region Hong Kong, China. The socioeconomic status each TPU was measured by social deprivation index (SDI) derived...
BackgroundLittle is known about the effect of physical exercise on influenza-associated mortality.Methods and FindingsWe collected information habits other lifestyles, socioeconomic demographic status, underlying cause death 24,656 adults (21% aged 30–64, 79% 65 or above) who died in 1998 Hong Kong, weekly proportion specimens positive for influenza A (H3N1 H1N1) B isolations during same period. We assessed excess risks (ER) mortality due to all-natural causes, cardiovascular diseases,...
Both influenza viruses and air pollutants have been well documented as major hazards to human health, but few epidemiologic studies assessed effect modification of on health effects ambient pollutants.We aimed assess modifying applied Poisson regression daily numbers hospitalizations mortality develop core models after adjustment for potential time-varying confounding variables. We by adding variables concentrations single proportions influenza-positive specimens (influenza intensity) their...
Hong Kong has the highest breast cancer incidence in Asia and studying secular changes its rates may lead to hypotheses regarding disease aetiology also predictions of future trends for China. We examined statistics from Cancer Registry based on 26 566 cases invasive 1973 1999. The were studied using log-linear longitudinal models. further analysed independent effects chronological age, time period birth cohort age-period-cohort modelling. average annual per cent change age-standardised was...
Sick building syndrome (SBS) is a condition affecting occupants of from which they may experience series non-specific symptoms being in that building. We aimed to (1) estimate the prevalence SBS (2), assess association between perceived indoor environmental quality (IEQ) aboveground and underground workspaces, what extent workspace location modifies these associations. A total 329 workers workspaces were followed-up three assessments for 12 months Singapore. Data on socio-demographic...
Please cite this paper as: Wong et al. (2012) Cigarette smoking as a risk factor for influenza‐associated mortality: evidence from an elderly cohort. Influenza and Other Respiratory Viruses 7(4), 531–539. Background The effects of individual lifestyle factors on the mortality after influenza infection have not been explored. Objectives In study, we assessed modifying cigarette risks associated with in cohort Hong Kong elders follow‐up period 1998–2009. Methods We used Cox proportional...