- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Cerebrospinal fluid and hydrocephalus
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Liver Disease and Transplantation
- Neurosurgical Procedures and Complications
- Bone fractures and treatments
- Moyamoya disease diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Total Knee Arthroplasty Outcomes
- Hip and Femur Fractures
- Vascular Malformations Diagnosis and Treatment
- Hip disorders and treatments
- Simulation-Based Education in Healthcare
- Meningioma and schwannoma management
- Head and Neck Surgical Oncology
- Shoulder Injury and Treatment
- Neurological disorders and treatments
- Endoplasmic Reticulum Stress and Disease
- Genetic Neurodegenerative Diseases
- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Lower Extremity Biomechanics and Pathologies
- Adrenal and Paraganglionic Tumors
Universidade Federal do Pará
2003-2023
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2012-2021
Universidade de São Paulo
2000-2021
Centro Universitário do Pará
2017
The molecular mechanisms behind aneurysmal subarachnoid haemorrhage (aSAH) are still poorly understood. Expression patterns of miRNAs may help elucidate the post-transcriptional gene expression in aSAH. Here, we evaluate global profile (miRnome) patients with aSAH to identify potential biomarkers. We collected 33 peripheral blood samples (27 cerebral aneurysm, 7 10 days after haemorrhage, when usually is vasospasm risk peak, and six controls). Then, were performed small RNA sequencing using...
Background: There are no studies describing the cerebral hemodynamic patterns that can occur in traumatic brain injury (TBI) patients following decompressive craniectomy (DC). Such data have potentially clinical importance for guiding treatment. The objective of this study was to investigate postoperative patterns, using transcranial Doppler (TCD) ultrasonography, who underwent DC. relationship between circulatory and patients' outcome also analyzed. Methods: Nineteen TBI with uncontrolled...
Tumours of the Central Nervous System (CNS) are an important cause mortality from cancer. Epidemiological data on neoplams affecting CNS scarce in Brazil, especially Amazon region. The study aims at describing histopathological profile tumours cases a high-complexity referral cancer center. This has described 17-year-series tumours, registered center Pará state, January 1997 until July 2014 Brazilian Region. Data was gathered histopathology reports kept hospital's registry and 949 were...
ABSTRACT Background: Simulations are becoming widely used in medical education, but there is little evidence of their effectiveness on neurocritical care. Because acute stroke a neurological emergency demanding prompt attention, it promising candidate for simulation training. Objective: To assess the impact realistic course clinicians’ self-perception confidence management stroke. Methods: We conducted controlled, before-after study. For our intervention, 17 healthcare professionals...
Neurofibromatosis type 1 is characterized by nerve sheath neurofibromas associated with a number of additional clinical features, including cerebrovascular disease. The aim this study was to use transcranial Doppler as screening method for identifying cerebral vasculopathy in children neurofibromatosis 1. Forty 1, aged 5 18 years old, were examined Doppler. Patients presenting hemodynamic features arterial stenosis/occlusion on underwent magnetic resonance angiography confirm the findings....
Introduction . Cerebral emboli may occur in subarachnoid hemorrhage (SAH) and intracranial aneurysm surgery. Although embolic signs (ES) have been reported SAH, their origin remains unclear. The aim of this study was to report the detection ES during routine TCD monitoring patients with aneurysmal SAH. Methods A total 105 SAH were submitted evaluation. Patients monitored almost daily (5 times per week). In each session, one experienced operator performed detect or assess vasospasm arteries...
Title: Persistent post-traumatic orbital cerebrospinal fluid fistula with multiple episodes of meningitis: a systematic review and case reportBackground: Orbital (CSF) fistulas are very rare. Most these spontaneously heal within couple days usually do not require surgical repair. Furthermore, they present low rates complications. Case presentation: We report 15-year-old boy that suffered penetrating head trauma developed meningitis due to persistent nasal CSF fistula. He underwent different...
Describe a case of cerebral proliferative angiopathy in patient with disabling headaches which we noticed CPA lesion shrinkage the use betablocker. Report clinical details, radiographic and angiogram findings medical management based on MOOSE Guidelines. The described this paper is about young man who, at first, complained headache migraine characteristics. Headaches became disabling. According to international protocols for treatment migraine, prophylactic tricyclics beta-blockers...
Uma série de 103 casos fraturas diafisárias complexas do fêmur foram tratadas com a haste intramedular bloqueada FMRP, no período maio 1987 dezembro 1995. Das fraturas, 67 eram cominutivas, 12 bifocais (segmentar), 4 espirais, 13 proximais e 21 distais, instáveis, rotacionalmente, da diáfise femoral. Do total dos casos, constatou-se 97 bloqueios estáticos 6 dinâmicos. Dessas estáticas, 7 dinamizadas durante evolução. Clínica radiográficamente consolidação ocorreu em 97,09% média 16,72...
Sickle-cell disease (SCD) is the most common cause of ischemic stroke in children and it happens about 11% patients between age 2 20 years old. About 7% world population affected by hemoglobin disorders, mostly sickle cell anemia. SCD has a high prevalence African offspring public health problem Brazil that affects more than 30,000 million people. Prevention primary might be feasible with way to identify at greatest risk. Transcranial Doppler Ultrasonography (TCD) can valuable service...
Introduction: The molecular mechanisms behind aneurysmal subarachnoid haemorrhage (aSAH) are still poorly understood. Expression patterns of miRNAs may help elucidate the post-transcriptional gene expression in aSAH.