A5081442197- Genomics and Phylogenetic Studies
- Bacteriophages and microbial interactions
- RNA and protein synthesis mechanisms
- Viral gastroenteritis research and epidemiology
- Microbial Community Ecology and Physiology
- Respiratory viral infections research
- Virus-based gene therapy research
- Chromosomal and Genetic Variations
- Gene expression and cancer classification
- Diphtheria, Corynebacterium, and Tetanus
- Bacterial Identification and Susceptibility Testing
- Animal Virus Infections Studies
- Environmental DNA in Biodiversity Studies
- Insect symbiosis and bacterial influences
- Healthcare Regulation
- Mycobacterium research and diagnosis
- Scientific Computing and Data Management
- Renal and related cancers
- Biofuel production and bioconversion
- Parvovirus B19 Infection Studies
- COVID-19 and Mental Health
- Education during COVID-19 pandemic
- Microbial Metabolism and Applications
- Trypanosoma species research and implications
- Streptococcal Infections and Treatments
Ministério da Saúde
2021-2025
Universidade Federal do Pará
2016-2024
Instituto Evandro Chagas
2023-2024
Ministério da Saúde
2024
Acute gastroenteritis (AG) is a major illness in early childhood. Recent studies suggest potential association between human bocavirus (HBoV) and AG. HBoV, non-enveloped virus with single-strand DNA genome, belongs to the Parvoviridae family. This study aimed describe frequency of HBoV Northern Brazil using samples from patients AG collected 2017 2022. Fecal obtained viral surveillance network at Evandro Chagas Institute (IEC) were analyzed. suspensions (20%) prepared, genome was extracted....
The advent of NGS (Next Generation Sequencing) technologies has resulted in an exponential increase the number complete genomes available biological databases. This advance allowed development several computational tools enabling analyses large amounts data each various steps, from processing and quality filtering to gap filling manual curation. developed for closure are very useful as they result more genomes, which will influence downstream genomic plasticity comparative genomics. However,...
Abstract Aims The present study aimed to use a conventional and metagenomic approach investigate the microbiological diversity of water bodies in network drainage channels rivers located central area city Belém, northern Brazil, which is considered one largest cities Brazilian Amazon. Methods results In eight analyzed points, both bacterial viral indicators environmental contamination—physical–chemical metals—were assessed. resistance genes, drug mechanisms, viability environment were also A...
Viral gastroenteritis is commonly reported in dogs and involves a great diversity of enteric viruses. In this research, viral was investigated with diarrhea Northern Brazil using shotgun metagenomics. Furthermore, the presence norovirus (NoV) 282 stool/rectal swabs young/adult or without from two public kennels, based on one-step reverse transcription polymerase chain reaction (RT-PCR) for genogroup VI VII (GVI GVII) real-time RT-PCR GI, GII, GIV. Thirty-one families were identified,...
This work reports on the whole-genome sequencing of Leishmania infantum chagasi from Honduras (Central America) and Brazil (South America).
Abstract High-throughput sequencing technologies are a milestone in molecular biology for facilitating great advances genomics by enabling the deposit of large volumes biological data to public databases. The availability such has made possible comparative genomic analysis through pipelines, using entire gene repertoire genomes. However, number unfinished genomes exist databases; their is approximately 16-fold higher than complete genomes, which creates bias during analyses. Therefore,...
Herein, we present the draft genome of Trametes villosa isolate CCMB561, a wood-decaying Basidiomycota commonly found in tropical semiarid climate. The assembly was 57.98 Mb size with an L50 691. A total 16,711 putative protein-encoding genes predicted, including 590 coding for carbohydrate-active enzymes (CAZy), directly involved decomposition lignocellulosic materials. This is first this species high interest bioenergy research. CCMB561 will provide important resource future investigations...
Despite the importance of understanding ecology freshwater viruses, there are not many studies on subject compared to marine viruses. The microbiological interactions in these environments still poorly known, especially between bacteriophages and their host bacteria cyanophages cyanobacteria. Lake Bologna, Belém, capital Brazilian State Pará, is a water source that supplies city its metropolitan region. However, it remains unexplored regarding contents virome viral diversity composition....
Corynebacterium pseudotuberculosis is the causative bacterial agent of zoonotic disease known as caseous lymphadenitis, and it presents several mechanisms response to host defenses, including presence virulence factors (VFs). The genomes these bacteria have polymorphic markers microsatellites, or simple sequence repeats (SSRs), that can be used characterize genome, study possible polymorphisms existing among strains, verify effects such in coding regions associated with VFs. In this study,...
The canine circovirus (CanCV) is a single-stranded DNA virus that has become an important emerging associated with gastroenteritis in dogs worldwide. In the present study, CanCV was detected by PCR 15% (22/147) of from animal shelters Belém, between 2019 and 2020. We observed association infection presence diarrhea animals younger than one year age (p > 0.01). Brazilian strains were grouped Chinese genotypes, 99.54 to 100% nucleotilde homology. GMRF Bayesian Skyride used molecular clock...
In reproductive technologies, uncovering the molecular aspects of oocyte and embryo competence under different conditions is crucial for refining protocols enhancing efficiency. RNA-seq generates high-throughput data provides transcriptomes that can undergo additional computational analyses. This study presented transcriptomic profiles
Abstract Background Tandem repeats are specific sequences in genomic DNA repeated tandem that present all organisms. Among the subcategories of TRs we have Satellite repeats, is divided into macrosatellites, minisatellites, and microsatellites, being last two interest because they can identify polymorphisms between organisms due to their instability. Currently, most mining tools focus on Simple Sequence Repeats (SSR) mining, only a few SSRs coding regions. Results We developed microsatellite...
The coronavirus disease-2019 (COVID-19) pandemic has affected different sectors of society, and healthcare workers have been particularly impacted. This study aimed to describe the clinical, epidemiological, molecular characteristics SARS-CoV-2 infections among in Evandro Chagas Institute, a research reference center Brazil, from October 2020 July 2022. 845 samples were collected individuals who presented clinical symptoms respiratory infection. Nasopharyngeal positive submitted through...
Keywords: Human Bocavirus; Acute Gastroenteritis; Viral Coinfection; Genotypes.
In Brazil, training capable bioinformaticians is done, mostly, in graduate programs, sometimes with experiences during the undergraduate period. However, this formation tends to be inefficient attracting students area and mainly professionals support research projects groups. To solve these issues, participation short courses important for usage of tools specific areas that use bioinformatics, as well ways develop solutions tailored local needs academic institutions or aim, project...
ABSTRACT We report here the draft genome sequence of Corynebacterium pseudotuberculosis PA05, isolated from an ovine host in Pará State, Brazil. C. is etiological agent diseases with veterinary and medical importance. The contains 2,435,137 bp, a G+C content 52.2%, 2,295 coding sequences, five pseudogenes, 53 tRNAs, six rRNAs.
Abstract Background: Despite the importance of understanding ecology freshwater viruses, there are not many studies on issue when compared to marine viruses. The microbiological interactions that occur in these environments still poorly known, especially between bacteriophages and their host bacteria, as well cyanophages cyanobacteria. Lake Bologna, from Belém, capital Brazilian State Pará, is a source water supplies city its metropolitan region, yet it remains unexplored regarding contents...