- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Mental Health Research Topics
- Neural dynamics and brain function
- Child and Adolescent Psychosocial and Emotional Development
- Treatment of Major Depression
- Transcranial Magnetic Stimulation Studies
- Maternal Mental Health During Pregnancy and Postpartum
- Neural and Behavioral Psychology Studies
- Schizophrenia research and treatment
- Advanced MRI Techniques and Applications
- Neuroscience and Music Perception
- Child Abuse and Trauma
- Hearing Loss and Rehabilitation
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Traumatic Brain Injury Research
- Stress Responses and Cortisol
- Tryptophan and brain disorders
- Spatial Neglect and Hemispheric Dysfunction
- Genetic Associations and Epidemiology
- Psychosomatic Disorders and Their Treatments
- Ophthalmology and Visual Impairment Studies
- Face Recognition and Perception
- Fractal and DNA sequence analysis
- Trigeminal Neuralgia and Treatments
Guangzhou Medical University
2016-2025
Beijing Haidian Hospital
2024
Health First
2024
Guangzhou Psychiatric Hospital
2014-2022
Guangdong 999 Brain Hospital
2015-2019
University of Electronic Science and Technology of China
2015-2017
Guangdong General Hospital
2015
Guangdong Academy of Medical Sciences
2015
South China University of Technology
2015
The right hemispheric dominance in visuospatial attention human brain has been well established. Converging evidence documented that ventral posterior parietal cortex (PPC) plays an important role attention. of dorsal PPC subregions, especially the superior lobule (SPL) is still controversial. In current study, we used repetitive transcranial magnetic stimulation (rTMS) and diffusion resonance imaging (MRI) techniques to test SPL investigate potential neuroanatomical basis for hemisphere...
Background:Cognitive impairment is a key feature of treatment-resistant depression (TRD) and can be related to the anterior cingulate cortex (ACC) function. Repetitive transcranial magnetic stimulation (rTMS) as an antidepressant intervention has increasingly been investigated in last two decades. However, no studies date have association between neurobiochemical changes within executive dysfunction measured TRD being treated with rTMS.
Major depressive disorder (MDD) is one of the most prevalent mental disorders. In brain, hubs brain network play a key role in integrating and transferring information between different functional modules. However, whether changed pattern contributes to onset MDD remains unclear. Using resting-state magnetic resonance imaging graph theory methods, we investigated alterations can be detected MDD. First, constructed whole-brain voxel-wise networks calculated connectivity strength (FCS) map...
Abstract Childhood maltreatment (CM) confers a great risk of maladaptive development outcomes later in life, however, the neurobiological mechanism underlying this vulnerability is still unclear. The present study aimed to investigate long‐term consequences CM on neural connectivity while controlling for psychiatric conditions, medication, and, substance abuse. A sample including adults with ( n = 40) and without 50) completed Trauma Questionnaire (CTQ), personality questionnaires,...
Childhood trauma (CT) is a non-specific risk factor for major depressive disorder (MDD). However, the neurobiological mechanisms of MDD with CT remain unclear. In present study, we sought to determine specific brain regions associated and etiology. Fractional amplitude low-frequency fluctuation (fALFF) functional connectivity (FC) analyses were performed assess alterations intrinsic activity in CT, without healthy controls CT. Two-by-two factorial examine effects factors "MDD" "CT" on fALFF...
Affective temperaments have been considered antecedents of major depressive disorder (MDD). However, little is known about how the covariation between alterations in brain activity and distinct affective work collaboratively to contribute MDD. Here, we focus on insular cortex, a critical hub for integration subjective feelings, emotions, motivations, examine neural correlates their relationship symptom dimensions.Twenty-nine medication-free patients with MDD 58 healthy controls underwent...
Background Schizophrenia is a complex mental disorder with high heritability and polygenic inheritance. Multimodal neuroimaging studies have also indicated that abnormalities of brain structure function are plausible neurobiological characterisation schizophrenia. However, the effects schizophrenia on these imaging endophenotypes not yet been fully elucidated. Aims To investigate risk for grey matter volume functional connectivity, which disrupted in Method Genomic data from large sample Han...
Abstract Childhood maltreatment (CM) has a long impact on physical and mental health of children. However, the neural underpinnings CM are still unclear. In this study, we aimed to establish associations between functional connectome large‐scale brain networks influences evaluated through Trauma Questionnaire (CTQ) at individual level based resting‐state magnetic resonance imaging data 215 adults. A novel mapping approach was employed identify subject‐specific network connectivities (FNCs)....
To date, the relationships between childhood neglect, hypothalamic-pituitary-adrenal (HPA) axis functioning and dysfunctional attitude in depressed patients are still obscure. The Childhood Trauma Questionnaire (CTQ) was used to assess emotional neglect physical neglect. Twenty-eight with 30 without from Guangzhou Psychiatric Hospital were compared 29 age- gender-matched control subjects 22 Cortisol awakening response, difference cortisol concentrations at minutes later, provided a measure...