- Radiopharmaceutical Chemistry and Applications
- Shoulder Injury and Treatment
- Shoulder and Clavicle Injuries
- Neuroendocrine Tumor Research Advances
- Lung Cancer Research Studies
- Immunotherapy and Immune Responses
- Neuroblastoma Research and Treatments
- Prostate Cancer Treatment and Research
- Medical Imaging Techniques and Applications
- vaccines and immunoinformatics approaches
- Prostate Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Metastasis and carcinoma case studies
- Cardiovascular Syncope and Autonomic Disorders
- Management of metastatic bone disease
- Cancer Diagnosis and Treatment
- T-cell and B-cell Immunology
- Salivary Gland Tumors Diagnosis and Treatment
- Thermal Regulation in Medicine
- Sarcoidosis and Beryllium Toxicity Research
- Occupational and environmental lung diseases
- Vasculitis and related conditions
- Otitis Media and Relapsing Polychondritis
- Thermoregulation and physiological responses
- Radiation Dose and Imaging
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori
2009-2022
Azienda Unità Sanitaria Locale Della Romagna
2017-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2014-2022
Ospedale G.B. Morgagni - L.Pierantoni
2004-2020
Ospedale Cervesi di Cattolica
2019
Policlinico S.Orsola-Malpighi
1996-1998
BACKGROUND: Dendritic Cell (DC) vaccination is a very promising therapeutic strategy in cancer patients. The immunizing ability of DC critically influenced by their migration activity to lymphatic tissues, where they have the task priming naïve T-cells. In present study vivo was investigated within context clinical trial antitumor vaccination. particular, we compared mature Cells (mDC) with that immature (iDC) and also assessed intradermal versus subcutaneous administration. METHODS: were...
Aims and background Bone metastases are responsible for high morbidity in cancer patients. The frequency of pain other serious complications associated with such depends on the site type lesions preventive therapy. present paper aims to inform scientific community about a new organizational health care model specifically designed patients bone metastases, hope stimulating creation similar initiatives whose goals decrease this pathology, reduce complications, limit psychophysical distress...
Talc pleurodesis (TP) is employed worldwide for the management of persistent pneumothorax or pleural effusion, particularly malignant origin. However, there are very little available data on (18)F-fluorodeoxyglucose positron-emission tomography/computed tomography ((18)F FDG PET/CT) response evaluation in mesothelioma (MPM) patients treated with TP and chemotherapy.Patients histologically confirmed MPM underwent PET/CT staging restaging after 3-4 courses chemotherapy. All fasted received a...
Neuroendocrine tumors (NETs) are rare neoplasms frequently characterized by an upregulation of the mammalian rapamycin targeting (mTOR) pathway resulting in uncontrolled cell proliferation. The mTOR is also involved skeletal muscle protein synthesis and adipose tissue metabolism. Everolimus inhibits pathway, blockade growth tumor progression. aim this study to investigate role body composition indexes patients with metastatic NETs treated everolimus. population included 30...
Background: We present a retrospective analysis of metronomic capecitabine in metastatic gastroenteropancreatic neuroendrocrine tumors (GEP-NETs). A review the literature is also presented. Methods: From January 2007 to December 2013, ten patients with GEP-NETs (four pancreatic and six ileal) who progressed after treatment somatostatin analogs other cytotoxic agents received oral 1,500 mg/day continuously. The median patient age was 68 (range 29–82) years. duration 8 months. Results: Five...
Malignant tumors of the lacrimal gland are rare, and single bone metastases from carcinoma an exceptional event. We present case a 71-year-old man with history lumbar pain left exophthalmos. Surgical resection lesion biopsy gave final histopathological diagnosis primary ductal adenocarcinoma metastasis. The pathological tissue both procedures was positive for androgen receptor expression. patient underwent embolization radiotherapy in association total blockade. After 20 months, is still...
A patient with resected stage III nodular melanoma treated high-dose interferon-α-b2 adjuvant therapy went on to develop generalized lymphadenopathy and splenomegaly. The total body positron emission tomography showed a high 18F-fluorodeoxyglucose uptake (standardized values >9), indicating possible lymph node spleen malignancies. Histologic examinations of an axillary biopsy osteomedullar were negative, excluding both metastases hematopoietic tumors. symptoms completely regressed after...
The recovery of scapular and humeral physiological kinematic parameters, as well the sensorimotor control movement, plays a primary role in rehabilitation process after arthroscopic rotator cuff repair. A highly customized approach is required to achieve this aim. Biofeedback can be useful tool, but there poor evidence its application tear repair.The aim paper outline an innovative exercise-based program exploiting visual biofeedback for patients arthroscopically treated repair.For...
Dendritic Cell (DC) vaccination is a very promising therapeutic strategy in cancer patients. The immunizing ability of DC critically influenced by their migration activity to lymphatic tissue, where they prime naive T cells. In the present study were differentiated from PBMC obtained leukapheresis (7-day culture adherent cells with IL-4 and GM-CSF). On day 7 defined as immature (iDC). After transient (3 h) continuous (48 stimulation cocktail cytokines (IL-1β, IL-6, TNF-α, PGE2), iDC...
20694 Background: Bone metastases are responsible for high morbidity in cancer patients. Multidisciplinary treatment is essential and should aim at decreasing the frequency of complications (pain, pathological fractures, spinal cord compression, bone marrow suppression hypercalcemia), improving quality life prolonging survival. Methods: In January 2005 an Osteo-Oncology Center was opened our Oncology Department. An oncologist coordinates a team 18 specialists palliative care, radiotherapy,...