- Intracranial Aneurysms: Treatment and Complications
- Meningioma and schwannoma management
- Traumatic Brain Injury and Neurovascular Disturbances
- Glioma Diagnosis and Treatment
- Vascular Malformations Diagnosis and Treatment
- Neurosurgical Procedures and Complications
- Cerebrovascular and Carotid Artery Diseases
- Head and Neck Surgical Oncology
- Spinal Fractures and Fixation Techniques
- Nanoplatforms for cancer theranostics
- Aortic Disease and Treatment Approaches
- Acute Ischemic Stroke Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Moyamoya disease diagnosis and treatment
- Spine and Intervertebral Disc Pathology
- Neurofibromatosis and Schwannoma Cases
- Fetal and Pediatric Neurological Disorders
- Neuropeptides and Animal Physiology
- S100 Proteins and Annexins
- Cervical and Thoracic Myelopathy
- Photoacoustic and Ultrasonic Imaging
- Cardiovascular Health and Disease Prevention
- Teratomas and Epidermoid Cysts
- Long-Term Effects of COVID-19
- CNS Lymphoma Diagnosis and Treatment
Nuremberg Hospital
2024
Paracelsus Medizinische Privatuniversität
2024
University of Regensburg
2007-2023
University Hospital Regensburg
2010-2022
Liv Hospital
2018
Istinye University
2018
University Medical Center
2013
University of California, Los Angeles
2013
Abstract Purpose: Sodium fluorescein is a dye that, intravenously injected, selectively accumulates in high-grade glioma (HGG) tissue through damaged blood–brain barrier. In this article, the final results of multicentric prospective phase II trial (FLUOGLIO) on fluorescein-guided HGG resection dedicated filter surgical microscope were reported. Methods: Patients with suspected HGGs considered suitable for removal eligible to participate trial. Fluorescein was injected at dose 5 10 mg/kg....
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) profoundly impacts hemostasis and microvasculature. In the light of dilemma between thromboembolic hemorrhagic complications, in present paper, we systematically investigate prevalence, mortality, radiological subtypes, clinical characteristics intracranial hemorrhage (ICH) disease (COVID-19) patients.
OBJECT The underlying mechanisms causing intracranial perianeurysmal edema (PAE) are still poorly understood. Since PAE is most frequently observed in giant aneurysms (GIAs), the authors designed a study to examine occurrence of relation location, size, and partial thrombosis (PT) GIAs along with clinical impact PAE. METHODS Magnetic resonance imaging data for patients diagnosis unruptured GIA from international multicenter Giant Intracranial Aneurysm Registry were retrospectively analyzed...
<i>Background:</i> The pathophysiology of ischemic cerebral lesions following aneurysmal subarachnoid hemorrhage (SAH) is poorly understood. There growing evidence that inflammatory reactions could be involved in the pathogenesis such delayed occurring lesions. aim this study was to evaluate adhesion molecules with regard these SAH. <i>Methods:</i> Serum and cerebrospinal fluid (CSF) samples were taken daily from 15 patients up day 9 after SAH evaluated for...
Despite technical and diagnostic progress there are still open questions in the understanding of pathophysiology intracranial aneurysms.Within 44 days we observed de novo genesis rupture an aneurysm basilar artery a patient. We performed computational fluid dynamics on 3-dimensional (3D) models inconspicuous vessel same with aneurysm. Based simulations propose mechanism fast-growing aneurysms.Three-dimensional mesh were built using computed tomography-angiography slices. Flow was modeled as...
Intraoperative aneurysm rupture is associated with a high morbidity and mortality. Temporary vessel occlusion an integral part of clipping to avoid intraoperative hemorrhage. The information concerning the role temporary regarding development cerebral vasospasm sparse. aim this study was provide more in field.We operated on 292 patients suffering from aneurysms. data were reviewed prospectively collected databank, which includes about severity subarachnoid hemorrhage, as well transcranial...
Background Diagnostic accuracy studies of neuromonitoring devices during carotid endarterectomy in awake patients are limited by the question transferability to anesthetized patients. This study was designed compare different parameters under regional and general anesthesia with stump pressure as primary endpoint courses cerebral blood flow velocity (Vmca) measured transcranial Doppler sonography, oxygen saturation (rSO2) near-infrared spectroscopy, amplitude somatosensory evoked potentials...
OBJECTIVE Well-documented case reports of the rapid formation and rupture de novo aneurysms posterior circulation are rare. CLINICAL PRESENTATION We report a patient with subarachnoid hemorrhage caused by an aneurysm anterior communicating artery that was clipped consecutively. Forty-four days after initial hemorrhage, experienced second newly grown basilar tip. Between two hemorrhages, transcranial Doppler sonography neuroimaging revealed fulminant generalized vasospasm. INTERVENTION To our...
With decompressive craniectomy for ischemic stroke, traumatic brain injury, and skull-infiltrating tumors, the need cranioplasty has increased. Different materials custom-made cranioplasties have been evaluated, but a gold standard could not yet be established. We report our experience with new titanium CRANIOTOP(®)cranioplasty (CL Instruments, Germany).A total of 50 consecutive patients received CRANIOTOP within 2 year interval. reviewed charts time between initial surgery cranioplasty,...
Background: Cognitive decline, slow psychomotor regression and confusion, especially in the elderly, often result medical consultation. Frequently, these rather unspecific symptoms are interpreted as signs of beginning dementia. When mental is joined by tremor or motor deficits, neurodegenerative disease commonly considered need for neuroimaging underestimated. Chronic subdural haematoma (CSH) known to be most frequent type intracranial bleeding, appearing mostly elderly after minor trauma...