A5081276175- Inorganic and Organometallic Chemistry
- History and advancements in chemistry
- Finite Group Theory Research
- Biomedical and Chemical Research
- Myasthenia Gravis and Thymoma
- Virology and Viral Diseases
- Advanced Topics in Algebra
- Rings, Modules, and Algebras
- Synthesis and characterization of novel inorganic/organometallic compounds
- Long-Term Effects of COVID-19
- Organometallic Complex Synthesis and Catalysis
- Chemical Synthesis and Reactions
- Chemistry and Chemical Engineering
- Ferrocene Chemistry and Applications
- Chemical Reactions and Mechanisms
- Molecular spectroscopy and chirality
- Antifungal resistance and susceptibility
- Tracheal and airway disorders
- Mosquito-borne diseases and control
- Catalysis and Oxidation Reactions
- Advanced Algebra and Logic
- Physics and Engineering Research Articles
- Radioactive element chemistry and processing
- History and Theory of Mathematics
- Peripheral Neuropathies and Disorders
University Hospital Regensburg
2015-2025
University of Regensburg
2020-2025
Deggendorf Institute of Technology
2022-2025
Klinik Donaustauf
2023
Klinik und Poliklinik für Neurologie
2020
Charité - Universitätsmedizin Berlin
2019
University Hospital Heidelberg
2019
University Medical Center
2019
Klinikum Kassel
2019
Heidelberg University
2019
Free products of groups with amalgamated subgroups, first introduced by Schreier (1927) and generalized Hanna Neumann (1948), are here redefined, studied applied to a number problems in abstract group theory. The applications mainly concerned existence embedding theorems. four chapters self-contained, requiring little beyond the fundamentals Only last chapter is use made theorems (Gruschko 1940; Kurosch 1934; 1949) which not proved here.
Abstract Background Comprehensive data on the cerebrospinal fluid (CSF) profile in patients with COVID-19 and neurological involvement from large-scale multicenter studies are missing so far. Objective To analyze systematically CSF COVID-19. Methods Retrospective analysis of 150 lumbar punctures 127 PCR-proven symptoms seen at 17 European university centers Results The most frequent pathological finding was blood-CSF barrier (BCB) dysfunction (median QAlb 11.4 [6.72–50.8]), which present...
To determine demographic characteristics, clinical features, treatment regimens, and outcome of myasthenic crisis (MC) requiring mechanical ventilation (MV).Analysis patients who presented with MC between 2006 2015 in a German multicenter retrospective study.We identified 250 cases 12 participating centers. Median age at was 72 years. duration MV days. Prolonged (>15 days) depended on (p = 0.0001), late-onset myasthenia gravis (MG), high Myasthenia Gravis Foundation America Class before...
Lactate formation in highly proliferative tumors such as malignant gliomas is associated with poor survival and contributes to the suppression of local immunity. Here, we report that diclofenac used at nontoxic concentrations significantly decreased lactate production murine glioma cells inhibited expression dehydrogenase-A vitro. reduction was accompanied by a dose-dependent inhibition cell growth cycle arrest G2/M checkpoint. In presence diclofenac, bone marrow-derived dendritic (DCs)...
After many years of controversy, there is now recent and solid evidence that classical Borna disease virus 1 (BoDV-1) can infect humans. On the basis six brain autopsies, we provide first systematic overview on BoDV-1 tissue distribution lesion pattern in fatal BoDV-1-induced encephalitis. All brains revealed a non-purulent, lymphocytic sclerosing panencephalomyelitis with detection BoDV-1-typical eosinophilic, spherical intranuclear Joest–Degen inclusion bodies. While composition...
More than 40 human cases of severe encephalitis caused by Borna disease virus 1 (BoDV-1) have been reported to German health authorities. In an endemic region in southern Germany, we conducted the seroepidemiological BoSOT study ("BoDV-1 after solid-organ transplantation") assess whether there are undetected oligo- or asymptomatic courses infection. A total 216 healthy blood donors and 280 outpatients solid organ transplantation were screened a recombinant BoDV-1 ELISA followed indirect...
Autoreactive CD4+ T lymphocytes play a vital role in the pathogenesis of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis. Since discovery helper 17 cells, there is an ongoing debate whether 1, or both subtypes are important for initiation neuroinflammation. We examined peripheral blood cells from patients with active stable relapsing–remitting sclerosis, used mice conditional deletion over-expression transforming growth factor-β inhibitor Smad7, to...
Borna disease virus 1 (BoDV-1) causes rare but often fatal encephalitis in humans. Late diagnosis prohibits an experimental therapeutic approach. Here, we report a recent case of BoDV-1 infection diagnosed on day 12 after hospitalization by detection RNA the cerebrospinal fluid. In retrospective analysis, detect hospital admission when cell count fluid is still normal. We develop new ELISA using recombinant nucleoprotein, phosphoprotein, and accessory protein X to seroconversion 12. Antibody...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) profoundly impacts hemostasis and microvasculature. In the light of dilemma between thromboembolic hemorrhagic complications, in present paper, we systematically investigate prevalence, mortality, radiological subtypes, clinical characteristics intracranial hemorrhage (ICH) disease (COVID-19) patients.
Background High-dose glucocorticoids are the standard treatment for acute relapses in patients with multiple sclerosis (MS) or neuromyelitis optica spectrum disorder (NMOSD). Therapeutic apheresis can be considered escalation of relapse therapy, but some still do not recover sufficiently. We aimed to explore effects on humoral and cellular immune parameters identify features that correlate beneficial clinical outcomes. Methods studied two cohorts comprising a total 63 MS NMOSD who were...