A5080006607- Blood groups and transfusion
- Erythrocyte Function and Pathophysiology
- Silk-based biomaterials and applications
- Protein Hydrolysis and Bioactive Peptides
- 3D Printing in Biomedical Research
- Enzyme Production and Characterization
- Immunodeficiency and Autoimmune Disorders
- Metabolomics and Mass Spectrometry Studies
- Ginseng Biological Effects and Applications
- Blood transfusion and management
- Hepatitis B Virus Studies
- Pineapple and bromelain studies
- Virus-based gene therapy research
- Glycosylation and Glycoproteins Research
- Machine Fault Diagnosis Techniques
- Congenital Diaphragmatic Hernia Studies
- Urological Disorders and Treatments
- Insect Utilization and Effects
- Image Enhancement Techniques
- Neutropenia and Cancer Infections
- Industrial Vision Systems and Defect Detection
- Prenatal Screening and Diagnostics
- Advanced Drug Delivery Systems
- Erythropoietin and Anemia Treatment
- Fecal contamination and water quality
Central People's Hospital of Zhanjiang
2024
Yulin Normal University
2022
Xi'an Jiaotong University
2022
Guangzhou University of Chinese Medicine
2022
Chinese Academy of Sciences
2022
Sun Yat-sen University
2022
Hunan University of Traditional Chinese Medicine
2020
Jiangsu Province Blood Center
2011-2017
Beijing Institute of Nutritional Sources
2016
Soochow University
2013-2014
Abstract Background Treatment options for refractory metastatic colorectal cancer (mCRC) were limited. Anlotinib is a novel multitarget tyrosine kinase inhibitor. ALTER0703 study was conducted to assess efficacy and safety of anlotinib patients with mCRC. Materials Methods This multicenter, double-blinded, placebo-controlled, randomized phase III trial involving 33 hospitals in China. Patients had taken at least two lines therapies 2:1 receive oral (12 mg/day; days 1–14; 21 per cycle) or...
The objective of this study was to investigate the effects environmental stress and emulsifier types on stability curcumin emulsions. Results showed that Lecithin Tween 80 presented good emulsifying capacity. emulsion most stable among four emulsions.The particle sizes whey protein were relatively smaller than gum arabic lecithin. Extensive droplet aggregation appeared in protein-stabilized emulsions when pH approximately isoelectric point (pI) with salt concentration >200 mM. unstable ≤ 6...
Bombyx mori silk fibroin is a macromolecular biopolymer with remarkable biocompatibility. It was degummed and subjected to series of treatments, including dissolution dialysis, yield an aqueous solution fibroin, which introduced rapidly into excess acetone produce crystalline nanoparticles (SFNs), were conjugated covalently naringinase using glutaraldehyde as the cross-linking reagent. The SFN naringinases are easily recovered by centrifugation can be used repeatedly. Naringinase bienzyme...
A novel sodium N-fatty acyl amino acid (SFAAA) surfactant was synthesized using pupa oil and protein hydrolysates (PPH) from a waste product of the silk industry. The aliphatic acids were modified into chlorides by thionyl chloride (SOCl2). SFAAA PPH. GC-MS analysis showed fatty consist mainly unsaturated linolenic linoleic saturated palmitic stearic acids. had low critical micelle concentration, great efficiency in lowering surface tension strong adsorption at an air/water interface. high...
The objective of this study was to improve silk floss processing technology. Silkworm (Bombyx mori) cocoons were quickly reeled into a raw sheet with cycling hot alkaline eluent in machine. refined the strongly electrolyzed water (SAEW) for 0.5 h, and (degummed fiber equivalent ∼40% (w/w) whole cocoons) obtained as material manufacture fabrics such quilts. refining solution separated by an ultrafilter, filtrate contained sericin oligomeric peptides free amino acids (SAA) low molecular mass,...
To explore the molecule basis of a p blood group in patient with gastric carcinoma.The phenotype was determined serological method. Inheritance investigated by pedigree analysis. Sequence α-1,4- galactosyltransferase (A4GALT) gene Sanger method.The proband and his younger brother were both to have phenotype. Two homozygous variations, c.343A>T (AAA>TAA) c.903C>G (CCC>CCG), been detected exon 3 A4GALT gene. Among these, c.343 A>T novel mutation, which has resulted termination codon, no normal...
Medial compartment knee osteoarthritis (KOA) accounts for most KOA cases, and increased trabecular bone volume fraction (BV/TV) is one of the pathological changes in tibial plateau KOA. How BV/TV before after menopause its effects on medial are yet to be clarified.Twenty femurs from twenty 12-week-old rats were included. The operated group underwent ovariectomy (to represent osteoporosis condition), called O group, non-operated was normal control, N group. Micro-CT scans femoral condyles...
The aim of this study was to investigate the molecular mechanism JK-null phenotype in Chinese population.The Jk(a-b-) is vanishingly rare and basis differs between ethnic groups. information regarding alleles population limited.Three unrelated donors were selected from 52 260 randomly blood samples through urea lysis test serological analysis. JK gene-coding regions amplified by polymerase chain reaction products sequenced directly.Sequencing results revealed that one sample JK(*) B carried...
Background Although periodic blood shortages are widespread in major Chinese cities, approximately 1x105 U of whole discarded yearly because under-collection. To reduce the wastage acid citrate dextrose solution B (ACD-B) anticoagulated under-collected (UC-WB), this study was performed to elucidate effect extracellular pH and holding time on erythrocyte quality. Mannitol-adenine-phosphate (MAP) concentrates (UC-RBCs) were prepared with UC-WB assess safety efficacy component. Methods The...
To verify the DNA sequence of a sample serologically identified as CisAB.Forward and reverse group methods were used to determine blood serological type that sample, PCR-sequence specific primer (PCR-SSP) method was for genotyping sample.Serologically, forward test showed AB, while had anti-B anti-H + +. The auto antibodies negative. PCR-SSP assay CisAB01. ABO genetic locus sequencing c.261delG in exon 6, c.297 homozygous AA. Mutations c.467C T c.803G C found 7. A novel heterozygous...
Porcine circovirus type 4 (PCV4) is a novel virus associated with porcine dermatitis and nephropathy syndrome (PDNS)-like signs identified firstly in China 2019. However, the details of molecular epidemiology PCV4 are unclear at this time. A total forty-two related sequences were selected from GenBank database to explore spread its rule genetic evolution. Of strains, 41 south 2019 2021 other was foreign representative strain. Phylogenetic tree construction, nucleotide amino acid (aa)...
Hepatitis B virus (HBV), hepatitis C (HCV), and human immunodeficiency (HIV) are life-threatening blood-borne infections that can be unintentionally transmitted in transfused blood products. Here, we optimized a method for detecting HBV, HCV, HIV-1 screening using magnetic nanoparticles (MNPs) polymerase chain reaction (PCR)-chemiluminescence. Viral genomes were extracted from donated samples MNPs. The isolated viral DNA RNA amplified one-step parallel reverse transcription-PCR (RT-PCR)....
Oxycodone hydrochloride is a semisynthetic narcotic analgesic agent. This study aimed to explore optimal titration strategy of controlled-release (CR) oxycodone in patients with cancer pain.258 patients, who used regular strong opioids (morphine and CR hydrochloride) for pain across 25 three grade class hospitals China during January 15th 2017 April 30th 2017, were retrospectively studied. The divided into 4 groups according treatment regimens titrated. remission rate numeric rating scale...
This study was purposed to analyses the serological and molecular basis of one sample A blood group which has anti-A. The tube method used detect phenotype, genotype amplified by PCR-SSP. sequence a-1-3-N-acetylgalactosaminyltransferase gene determined Sanger method. results showed that were discrepant. It as subtype firstly. result PCR-SSP existence O gene. sequencing 6th exon ABO c.261delG, refers specific amplification analysis carried out on 7th Two mutations in haplotype, c.467 C > T...
To explore the mechanism of ABO discrepancy in a patient by genotyping and reasonable blood transfusion strategy.Routine serological test was carried out to analyze group. The presence group determinants on red cells were determined adsorption-elution test. Exons 1-7 adjacent introns gene amplified PCR sequenced.The showed forward reverse typing discrepancy. defined as B, however, indicated that AB subtype. Absorption-elution confirmed weak A antigens patient's cells. sequencing T>C exchange...
Banding and doubling are two of the most common problems in inkjet printing, which caused by printheads defects including blocked nozzle poor registration. It is expensive inefficient to solve enhancing device accuracy or replacing defective printhead, since printhead may degrade over time. In this paper, we propose an economical efficient method for banding reduction detection without requirement hardware renewal. We design a test pattern composed specially organized dots diagnose status...
The aim of this study was to investigate the feasibility using RASSF1A gene as a universal fetal marker in maternal plasma. Two methods circulating cell-free DNA (cffDNA) extracted from plasma were compared. better one chosen for extraction cffDNA 20 pregnant samples. SRY and treated with methylation-sensitive restriction enzyme amplificated by RT-PCR PCR system optimized. results showed that found 11 out samples, which consistent postnatal sex. Using optimized system, specifically amplified...
Objective To establish technical standards and process protocol for MAP erythrocyte concentrates(RBCs),which were prepared from ACD-B anticoagulated under-collected whole blood(UC-WB) assess its security efficacy.Methods Thirty-four samples with UC-WB of minimum 66％ volume the labeled collection(UC-RBCs) divided into three groups according to store time.The indices related clinical application analyzed during 35 days storage.The effect UC-RBCs occurring adverse reactions in 56 patients blood...