Younes Esseddik
A5069558425- Nutritional Studies and Diet
- Consumer Attitudes and Food Labeling
- COVID-19 and Mental Health
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Obesity, Physical Activity, Diet
- Long-Term Effects of COVID-19
- Biochemical Analysis and Sensing Techniques
- SARS-CoV-2 detection and testing
- Vitamin C and Antioxidants Research
- Eating Disorders and Behaviors
- COVID-19 epidemiological studies
- Physical Activity and Health
- Diet and metabolism studies
- Nutrition, Genetics, and Disease
- Dye analysis and toxicity
- Olfactory and Sensory Function Studies
- COVID-19 Pandemic Impacts
- Dermatological and COVID-19 studies
- Folate and B Vitamins Research
- Animal Virus Infections Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Vitamin D Research Studies
- Blood groups and transfusion
- Advanced Chemical Sensor Technologies
Sorbonne Université
2020-2024
Centre de Recherche Épidémiologie et Statistique
2020-2024
Université Paris Cité
2020-2024
Conservatoire National des Arts et Métiers
2021-2024
Université Sorbonne Paris Nord
2020-2024
Inserm
2020-2024
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2021-2024
Equipe de Recherche en Epidémiologie Nutritionnelle
2020-2023
Sorbonne Paris Cité
2023
Santé Publique France
2021
After an infection by SARS-CoV-2, many patients present with persistent physical symptoms that may impair their quality of life. Beliefs regarding the causes these influence perception and promote maladaptive health behaviors.
Background The food industry uses artificial sweeteners in a wide range of foods and beverages as alternatives to added sugars, for which deleterious effects on several chronic diseases are now well established. safety these additives is debated, with conflicting findings regarding their role the aetiology various diseases. In particular, carcinogenicity has been suggested by experimental studies, but robust epidemiological evidence lacking. Thus, our objective was investigate associations...
Abstract Objectives To study the associations between artificial sweeteners from all dietary sources (beverages, but also table top sweeteners, dairy products, etc), overall and by molecule (aspartame, acesulfame potassium, sucralose), risk of cardiovascular diseases (overall, coronary heart disease, cerebrovascular disease). Design Population based prospective cohort (2009-21). Setting France, primary prevention research. Participants 103 388 participants web NutriNet-Santé (mean age...
Background Emulsifiers are widely used food additives in industrially processed foods to improve texture and enhance shelf-life. Experimental research suggests deleterious effects of emulsifiers on the intestinal microbiota metabolome, leading chronic inflammation increasing susceptibility carcinogenesis. However, human epidemiological evidence investigating their association with cancer is nonexistent. This study aimed assess associations between additive risk a large population-based...
Abstract Background. More than 330 food additives (e.g. artificial sweeteners, emulsifiers, dyes) are authorized in Europe, with a great variability of use across products. Objective. The objective this study was to investigate the distribution and co-occurrence large-scale database foods beverages available on French market. Design. open access crowdsourced Open Food Facts ( https://world.openfoodfacts.org/ ) used retrieve composition beverage products commonly marketed market (n =...
ABSTRACT Background Since December 2019, the coronavirus disease (COVID-19) has massively spread, with overwhelming of health care systems and numerous deaths worldwide. To remedy this, several countries, including France, have taken strict lockdown measures, requiring closure all but essential places. This unprecedented disruption daily routines a strong potential for disrupting nutritional behaviours. Nutrition being one main modifiable risk factors chronic risk, this may further...
We aimed to estimate the seropositivity anti-SARS-CoV-2 antibodies in May-June 2020 after first lockdown period adults living three regions France and identify associated risk factors.
Abstract Background To estimate the seroprevalence of SARS-CoV-2 infection in May-June 2020 after lockdown adults living three regions France and to identify associated risk factors. Methods Participants a survey on COVID-19 from an existing consortium general adult population cohorts Ile-de-France (IDF) or Grand Est (GE) - two with high rate COVID-19, Nouvelle-Aquitaine (NA) – low rate, were asked take dried-blood spot (DBS) for anti-SARS-CoV-2 antibodies assessment. The primary outcome was...
Food additives (e.g. artificial sweeteners, emulsifiers, dyes, etc.) are ingested by billions of individuals daily. Some concerning results, mainly derived from animal and/or cell-based experimental studies, have recently emerged suggesting potential detrimental effects several widely consumed additives. Profiles additive exposure as well the long-term impact multiple on human health poorly documented. This work aimed to estimate usual intake food among participants French NutriNet-Santé...
Nitrates and nitrites occur naturally in water soil. They are also used as food additives (preservatives) processed meats. could play a role the carcinogenicity of meat. The objective was to investigate relationship between nitrate nitrite intakes (natural food, additive sources) cancer risk large prospective cohort with detailed dietary assessment.
Importance Persistent symptoms after SARS-CoV-2 infection are an emerging public health problem. The duration of these remains poorly documented. Objective To describe the temporal dynamics persistent and factors associated with their resolution. Design, Setting, Participants This cross-sectional study involved 53 047 participants from 3 French adult population-based cohorts (CONSTANCES [Consultants des Centres d’Examens de Santé], E3N/E4N, Nutrinet-Santé) who were included in a nationwide...
OBJECTIVE To study the relationships between artificial sweeteners, accounting for all dietary sources (total and by type of sweetener) risk 2 diabetes (T2D), in a large-scale prospective cohort. RESEARCH DESIGN AND METHODS The analyses included 105,588 participants from web-based NutriNet-Santé (France, 2009–2022; mean age 42.5 ± 14.6 years, 79.2% women). Repeated 24-h records, including brands commercial names industrial products, merged with qualitative quantitative food additive...
Background Nitrites and nitrates occur naturally in water soil are commonly ingested from drinking dietary sources. They also used as food additives, mainly processed meats, to increase shelf life avoid bacterial growth. Experimental studies suggested both benefits harmful effects of nitrites exposure on type 2 diabetes (T2D) onset, but epidemiological clinical data lacking. We aimed study these associations a large population-based prospective cohort study, distinguishing foods...
Abstract Objective To assess the associations between exposure to food additive emulsifiers and risk of cardiovascular disease (CVD). Design Prospective cohort study. Setting French NutriNet-Santé study, 2009-21. Participants 95 442 adults (>18 years) without prevalent CVD who completed at least three 24 hour dietary records during first two years follow-up. Main outcome measures Associations intake (continuous (mg/day)) CVD, coronary heart disease, cerebrovascular characterised using...
When considering health-related impacts of foods, nutrient profile and (ultra)processing are two complementary dimensions. The Nutri-Score informs on the dimension. Recently, mounting evidence linked ultraprocessed food consumption to various adverse health outcomes, independently their profile. To inform consumers about each these dimensions food, we tested, in a randomised controlled trial, if graphically modified version 'Nutri-Score V.2.0', including black 'ultraprocessed' banner, would...
Nutritional factors are essential for the functioning of immune system and could therefore play a role in COVID-19 but evidence is needed. Our objective was to study associations between diet risk SARS-CoV-2 infection large population-based sample.Our analyses were conducted French prospective NutriNet-Santé cohort (2009-2020). Seroprevalence anti-SARS-CoV-2 antibodies assessed by ELISA on dried blood spots. Dietary intakes derived from repeated 24 h dietary records (at least 6) two years...
Background: To estimate the seroprevalence of SARS-CoV-2 infection in May-June 2020 after lockdown adults living three regions France and to identify associated risk factors.Methods: Participants a survey on COVID-19 from an existing consortia general adult population cohorts Ile-de-France (IDF) or Grand Est (GE) - two with high rate COVID-19, Nouvelle-Aquitaine (NA) – low rate, were asked take dried-blood spot (DBS) for anti-SARS-CoV-2 antibodies.The primary outcome was positive ELISA IgG...
Abstract ABO blood type has been reported as a potential factor influencing SARS-CoV-2 infection, but so far mostly in studies that involved small samples, selected population and/or used PCR test results. In contrast our study aimed to assess the association between types and infection using seroprevalence data (independent of whether or not individuals had symptoms sought for testing) large population-based sample. Our included 67,340 French participants SAPRIS-SERO multi-cohort project....
The individual results of SARS-CoV-2 serological tests measured after the first pandemic wave 2020 cannot be directly interpreted as a probability having been infected. Plus, these are usually returned binary or ternary variable, relying on predefined cut-offs. We propose Bayesian mixture model to estimate infection probabilities, based 81,797 continuous anti-spike IgG from Euroimmun collected in France wave. This approach used and was therefore not diagnostic Cumulative incidence, which is...
Assessment of the intensity, dynamics and determinants antibody response after SARS-CoV-2 infection or vaccination in general population is critical to guide policies. This study characterized anti-spike IgG titers 13,971 participants included a French multicohort population-based serological survey on COVID-19 between April October 2020 followed-up with testing May 2021. Eight follow-up profiles were defined depending (0, 1 2) 1, 2 3). The titer was lower adults no even case reinfection,...
Background: COVID-19 lockdowns represent natural experiments where limitations of movement impact on lifestyle behaviors. The aim this paper was to assess how have influenced physical activity and sedentary behaviors among French adults. Methods: 32,409 adults from the NutriNet-Santé study filled out questionnaires in April 2020 (the first 2 weeks after start lockdown) May (2 before lockdown ended). Participants were asked about changes level sitting time, types performed, main reasons for...
Abstract Background The interplay between age and symptoms intensity on antibody response to SARS-CoV-2 infection has not been studied in a general population setting. Methods We explored the serologic profile of anti-SARS-CoV-2 antibodies after first wave pandemic, by assessing IgG against spike protein (ELISA-S), nucleocapsid (ELISA-NP) neutralizing (SN) 82,126 adults from French population-based multi-cohort study. Results ELISA-S positivity was increased 30- 49-year-old (8.5%) compared...
Abstract Background Many hypotheses were raised regarding a role of nutrition in COVID-19 (susceptibility to infection, disease severity) based on the importance macronutrients, vitamins or minerals for proper functioning immune system. Our objective was study associations between dietary intakes and seroprevalence SARS-CoV-2 infection large population-based sample. Methods analyses included 7766 adults from French NutriNet-Santé cohort who provided at least 6 valid 24h records two years...
Abstract Context and objective When considering the health-related impact of foods, nutrient profile (content in salt, sugar, fibre, etc.) (ultra-)processing are two complementary dimensions. The Nutri-Score, a summary graded front-of-pack label, already used seven European countries, informs on dimension, i.e. one with strongest evidence. Recently, mounting evidence linked ultra-processed food consumption to various adverse health outcomes, independently their profile. To inform consumers...