A5100430099- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Geotechnical Engineering and Analysis
- Geotechnical Engineering and Underground Structures
- Cardiac Imaging and Diagnostics
- Medical Image Segmentation Techniques
- Bone Tissue Engineering Materials
- Brain Tumor Detection and Classification
- Advanced Radiotherapy Techniques
- AI in cancer detection
- Gut microbiota and health
- Retinal Imaging and Analysis
- Advanced X-ray and CT Imaging
- Thyroid Cancer Diagnosis and Treatment
- Smart Agriculture and AI
- Cancer-related molecular mechanisms research
- Radiation Dose and Imaging
- Geotechnical Engineering and Soil Stabilization
- Civil and Geotechnical Engineering Research
- Speech and Audio Processing
- Photonic Crystals and Applications
- Lung Cancer Diagnosis and Treatment
- Speech Recognition and Synthesis
- Mathematical and Theoretical Epidemiology and Ecology Models
- Dental Implant Techniques and Outcomes
General Hospital of Shenyang Military Region
2016-2025
Yanbian University
2024
Northeastern University
2018-2024
Qingdao University
2024
Affiliated Hospital of Qingdao University
2024
Shenyang Institute of Automation
2024
Chinese Academy of Sciences
2024
Shanghai Changzheng Hospital
2020-2023
Xi'an Jiaotong University
2023
Command Hospital
2021-2023
Recently, it has been reported that context-dependent deep neural network (DNN) achieved some unprecedented gains in many challenging ASR tasks, including the well-known Switchboard task. In this paper, we first investigate DNN for several large vocabulary speech recognition tasks. Our results have confirmed can consistently achieve about 25-30% relative error reduction over best discriminatively trained GMMs even tasks with up to 700 hours of training data. Next, conducted a series...
In vivo assessment of a novel artificial vertebral body fabricated by electron beam melting (EBM) for cervical replacement in sheep model.To investigate the feasibility body: "self-stabilizing body" (SSAVB) EBM model.Artificial is widely used and spinal fusion, but research on an has not been reported.An SSAVB made porous Ti6Al4V was implanted into spine to replace C4 6 12 weeks. Bone ingrowth implant stability were radiologically evaluated, histological biomechanical tests performed.No...
Probiotic intervention has beneficial effects on host brain function and behavior via regulating microbiota-gut-brain axis; however, the underlying mechanism is not yet understood. Herein, we investigated that of Lactobacillus plantarum DP189 (DP189) administration in preventing cognitive dysfunction pathology Alzheimer's disease (AD) D-galactose (D-gal) AlCl3-induced AD model mice. After L. for 10 weeks, assessed behavior, neurotransmitter expression, histological changes, microbial...
N4-methylcytosine (4mC) is a DNA modification involving the addition of methyl group to fourth nitrogen atom cytosine base. This may influence gene regulation, providing potential insights into control mechanisms. Traditional laboratory methods for detecting 4mC methylation have limitations, but rise artificial intelligence has introduced efficient computational strategies site prediction. Despite this progress, challenges persist in terms model performance and interpretability. To tackle...
Background Tau pathology is closely associated with brain atrophy and cognitive decline, but how it specifically influences local distant gray matter volume (GMV) function remains unclear. Objective This study aims to explore the spatial relationships between tau pathology, GMV cognition using hybrid positron emission tomography/magnetic resonance imaging (PET/MRI). Methods Twenty amyloid-β (Aβ)-positive Alzheimer's disease (AD) patients, 14 mild impairment (MCI) 22 Aβ-negative normal...
Automatic lymphoma detection and accurate boundary delineation from whole body Positron Emission Tomography/Computed Tomography (PET/CT) scans are essential for surgical navigation radiation therapy. Besides, labeling the data, which means contouring contour in images is time-consuming, operator intensive subjective. Hence, this paper integrates supervised learning unsupervised to propose an end-to-end segmentation network, namely DenseX-Net, both segmentation. There two important flows...
Abstract Background and Aim The gut microbiota is associated with colorectal lesions in cases of precancer cancer (CRC). However, there are apparent differences studies on the pathogenic sequence from to cancer. Here, we characterize signatures test their utility detecting two independent Chinese cohorts. Methods Stool samples collected patients CRC were subjected 16S ribosomal RNA gene sequencing metagenomic shotgun analyses, which revealed microbial disease stages. Results In comparison...
Double-O-tube shield tunneling has attracted increasing attention because it offers cost-efficiency in underground construction. Prediction of ground surface settlement and the variety additional stresses induced by construction is crucial to metropolises since excessive could trigger potential damage surrounding environment. The propulsion double-O-tube shields are calculated means Mindlin’s equations elasticity. characteristics analyzed with compound Gauss-Legendre integral arithmetic,...
Diabetic retinopathy (DR) and age-related macular degeneration (AMD) are forms of degenerative retinal disorders that may result in vision impairment or even permanent blindness. Early detection these conditions is essential to maintaining a patient's quality life. The fundus photography technique non-invasive, safe, rapid way assessing the function retina. It widely used as diagnostic tool for patients who suffer from fundus-related diseases. Using images analyze two diseases challenging...
Open biomass burning (OBB) in agriculture presents a significant and well-documented challenge, posing severe consequences for both environmental human health. OBB releases air pollutants that degrade quality contribute to climate change, leading premature deaths regions with high concentrations of open crop straw (OCSB) emissions. Although policies aimed at prohibiting are place, the efficacy these regulations mitigating OCSB emissions remains ambiguous. Consequently, early prevention...
Abstract Background Chemotherapy resistance is an important bottleneck affecting the efficacy of chemotherapy in colon cancer. Therefore, improving sensitivity colorectal cancer cells great significance for prognosis patients with Methods CCK-8 assay was employed to examine cell viability lines. Realtime-PCR and western blot were used explore toll-like receptor 4 (TLR4) expression The functions TLR4 stemness lines analyzed by infecting lentivirus containing siRNA. Results We found that...
Abstract Pathological scars (PS) are involved in the excessive response of inflammation and overactivation myofibroblasts. Herein, a novel microneedle (MN) patch based on adipose‐derived stem cell concentrated conditioned medium (ADSCC‐CM) cross‐linked keratin hydrogel is developed to load triamcinolone acetonide (TA), thereby achieving dual‐drug delivery ADSCC‐CM TA simultaneously reduce guide myofibroblast behaviors. Results not only confirm ability drive formation keratin‐based hydrogel,...
Background Various fabrication methods are used to improve the stability and osseointegration of screws within host bone. The aim this study was investigate whether roughened surface titanium fabricated by electron beam melting can provide better as compared with smooth in sheep cervical vertebrae. Methods Roughened screws, melting, conventional were implanted into for 6 or 12 weeks (groups A B, respectively). Bone ingrowth implant assessed three-dimensional imaging reconstruction, well...
An increasing number of studies reported that exogenous miRNAs (xenomiRs) can be detected in animal bodies, however, some others negative results. Some attributed this divergence to the selective absorption plant-derived xenomiRs by animals. Here, we analyzed 166 our previous study and 942 non-xenomiRs extracted from miRNA expression profiles four species commonly consumed plants. Employing statistics analysis cluster analysis, revealed potential sequence specificity xenomiRs. Furthermore, a...