A5029607878- Advanced MRI Techniques and Applications
- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Cardiac Imaging and Diagnostics
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Cardiac pacing and defibrillation studies
- Pediatric Hepatobiliary Diseases and Treatments
- Gallbladder and Bile Duct Disorders
- Cardiac Arrhythmias and Treatments
- Cardiac Valve Diseases and Treatments
- Pancreatic and Hepatic Oncology Research
- Cardiovascular Function and Risk Factors
- Artificial Intelligence in Healthcare and Education
- Sarcoidosis and Beryllium Toxicity Research
- Cardiac Fibrosis and Remodeling
- AI in cancer detection
- Transplantation: Methods and Outcomes
- Medical Imaging and Analysis
- Mesenchymal stem cell research
- Digital Radiography and Breast Imaging
- Nutritional Studies and Diet
- Electron Spin Resonance Studies
- Electrostatic Discharge in Electronics
- Ultrasound in Clinical Applications
Helsinki University Hospital
2014-2024
University of Helsinki
2015-2024
Imaging Center
2015-2020
Aalto University
2014-2017
Hospital District of Helsinki and Uusimaa
2015
Clinical Research Services
2014
Magnetic resonance imaging (MRI) instrumentation is vulnerable to technical and image quality problems, assurance essential. In the studied regional center long-term has been based on MagNET phantom measurements. American College of Radiology (ACR) an accreditation program including a standardized measurement protocol phantom. The ACR includes recommended acceptance criteria for clinical sequences thus provides possibility assess relevance assurance. purpose this study was test MRI in...
New treatment modalities are needed in atopic dermatitis. We evaluated the pharmacokinetics, safety, tolerability, and efficacy of topical cis-urocanic acid (cis-UCA) cream randomised vehicle-controlled double-blinded clinical trials. The subjects received 5% cis-UCA emulsion control vehicle on volar forearms after right–left randomisation. Study 1: 16 healthy one dose skin and, a week later, DMSO-irritated skin. 2: 2 daily doses for 10 days. 3: 13 patients with mild to moderate disease were...
Several studies have shown that cocoa and cocoa-containing foods the potential to lower blood pressure improve endothelial function. Most of reporting beneficial effects dark chocolate on been short (≤ 4 weeks). The aim present 8-wks (weeks) study was assess regular consumption during a reduced snack intervention other cardiovascular risk factors in mildly hypertensive individuals. This randomized, controlled, cross-over trial involving 22 adults (8 women, 14 men), aged 33–64 y, BMI 27.7 ±...
Two organic radical contrast agents, TEMPO-Glc and TEEPO-Glc, were synthesized their stabilities enhancing properties tested with <italic>in vitro</italic> NMR MRI experiments.
Background Magnetic resonance imaging (MRI) of pacemaker patients has become available despite previous contraindications. However, pacing systems containing ferromagnetic material may hamper the diagnostic quality cardiac MR (CMR) images. Purpose To study methods for reducing susceptibility-based artifacts in CMR examinations patients. Material and Methods Altogether 16 were scanned with 1.5T MRI scanner using cine balanced steady-state free-precession (bSSFP) spoiled gradient echo (SPGR)...
Aortic valve stenosis (AS) is the most prevalent valvular disease in developed countries. Four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) an emerging imaging technique, which has been suggested to improve evaluation of AS severity compared two-dimensional (2D) and transthoracic echocardiography (TTE). We investigated reliability CMR 2D 4D techniques measuring aortic transvalvular peak systolic patients with severe AS. prospectively recruited 90 referred for replacement due...
Computed tomography (CT) image noise is usually determined by standard deviation (SD) of pixel values from uniform regions. This study investigates how deep learning (DL) could be applied in head CT estimation.Two approaches were investigated for estimation a single acquisition image: direct using supervised DnCNN convolutional neural network (CNN) architecture, and subtraction denoised estimated with denoising UNet-CNN experimented unsupervised noise2noise training approaches. Noise was...
Abstract In human medicine, magnetic resonance cholangiopancreatography (MRCP) is a valuable diagnostic tool for hepatobiliary and pancreatic diseases. veterinary however, data evaluating the value of MRCP are limited. The primary objectives this prospective, observational, analytical investigation were to assess whether reliably visualizes biliary tract ducts in cats without with related disorders, images measurements agree those fluoroscopic retrograde (FRCP), corrosion casting...
Artificial intelligence (AI) applications are becoming increasingly common in radiology. However, ensuring reliable operation and expected clinical benefits remains a challenge. A systematic testing process aims to facilitate deployment by confirming software applicability local patient populations, practises, adherence regulatory safety requirements, compatibility with existing systems. In this work, we present our developed based on practical experience. First, survey pre-evaluation is...
Magnetic resonance cholangiopancreatography (MRCP) is commonly used in humans and also feasible cats. The aim of this post-mortem study was to investigate the feasibility MRCP eight adult dogs by comparing visibility measured diameters biliary tract pancreatic ducts with those fluoroscopic retrograde (FRCP) corrosion casting. In autopsy, six had no evidence hepatobiliary disorders, one pathology, pathology. gallbladder (GB), cystic duct, common bile duct (CBD) were visible images all dogs....
This study aimed to develop a deep learning (DL) method for noise quantification clinical chest computed tomography (CT) images without the need repeated scanning or homogeneous tissue regions.
Cone-beam computed tomography (CBCT) has become an increasingly important medical imaging modality in orthopedic operating rooms. Metal implants and related image artifacts create challenges for quality optimization CBCT. The purpose of this study was to develop a robust quantitative method the comprehensive determination metal novel CBCT applications.The O-arm device assessed with anthropomorphic pelvis phantom presence implants. Three different kilovoltage two exposure settings were used...
Bone marrow mononuclear cells (BMMCs) have been evaluated for their ability to improve cardiac repair and benefit patients with severe ischemic heart disease failure. In our single-center trial in 2006-2011 we demonstrated the safety efficacy of BMMCs injected intramyocardially conjunction coronary artery bypass surgery. The effect persisted follow-up study 5 years later. this study, investigated BMMC therapy beyond 10 years. A total 18 (46%) died during over 10-years 21 were contacted...
Abstract Magnetic resonance cholangiography (MRC) is an established diagnostic tool for noninvasive assessment of the biliary tract in humans. It has also been found to be feasible companion animals, but no published studies have compared MRC sequences veterinary medicine. The present study part a prospective, observational, analytical investigation on MR cholangiopancreatography performed donated bodies 12 cats and eight dogs. main aim this was compare images 2D‐SSh‐TSE‐MRC 3D‐TSE‐MRC...
Purpose: In addition to less frequent and more comprehensive tests, quality assurance (QA) protocol for a magnetic resonance imaging (MRI) scanner may include cursory daily or weekly phantom checks verify equipment constancy. With an automatic image analysis workflow, the QA images can be further used study baseline performance both long- short-term variations in quality. known baselines variation profiles, error detection employed. Approach: Four parameters were followed 17 MRI scanners...
Phantoms are often used to estimate the geometric accuracy in magnetic resonance imaging (MRI). However, distortions may differ between anatomical and phantom images. This study aimed investigate applicability of a phantom-based test-subject-based method evaluating distortion present clinical head-imaging sequences.We imaged 3D-printed test subjects with two MRI scanners using 3D sequences varying patient-table positions receiver bandwidths. The were evaluated through nonrigid registrations:...
Abstract Objectives: Patients with univentricular heart defects require lifelong imaging surveillance. Recent advances in non-invasive have enabled replacing these patients’ routine catheterisation. Our objective was to describe the safety and cost savings of transition a tertiary care children’s hospital from invasive low-risk patients defects. Methods: This single-centre cohort study consists 1) retrospective analysis cardiac catheterisation (n = 21) CT angiography 20) before bidirectional...
Abstract Funding Acknowledgements Type of funding sources: Public hospital(s). Main source(s): HUS Medical Imaging Center research grant Background The Heart and Rhythm Society’s consensus statement 2017 approves magnetic resonance imaging (MRI) with cardiac implantable electronic devices (CIED), but excludes patients epicardial abandoned leads. Potential safety hazards an MRI pacing leads include heating the tip lead induction current in resulting inappropriate stimulation. Only a few small...