A5112181736- Airway Management and Intubation Techniques
- Neonatal Respiratory Health Research
- Ocular Infections and Treatments
- Organ Transplantation Techniques and Outcomes
- Tracheal and airway disorders
- Antimicrobial Resistance in Staphylococcus
- Liver Disease and Transplantation
- Alcohol Consumption and Health Effects
- Respiratory Support and Mechanisms
- Systemic Sclerosis and Related Diseases
- Safe Handling of Antineoplastic Drugs
- Antibiotics Pharmacokinetics and Efficacy
- Family and Patient Care in Intensive Care Units
- Aortic aneurysm repair treatments
- Otitis Media and Relapsing Polychondritis
- Lung Cancer Treatments and Mutations
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Neonatal Health and Biochemistry
- Head and Neck Cancer Studies
- Health Systems, Economic Evaluations, Quality of Life
- Sharing Economy and Platforms
- Fungal Infections and Studies
- Organ Donation and Transplantation
- Heparin-Induced Thrombocytopenia and Thrombosis
Universidad de la República
2023
Hospital de Clínicas
2023
Universidad Complutense de Madrid
2014-2020
Hospital General Universitario Gregorio Marañón
2015-2020
Spanish Clinical Research Network
2020
Universitat de València
2016-2018
Hospital Universitario Virgen de la Arrixaca
2007
Andalusian School of Public Health
2003
Introduction. Multiple genetic and environmental factors interact with the development of acute coronary syndrome. Smoking is one that might alter metabolic pathways shared by genes associated this condition.Objective. To investigate association syndrome variants related to inflammation, lipid metabolism, platelet aggregation among subjects from northeastern region Colombia. The effects interactions between polymorphisms smoking were also evaluated.Materials methods. We analyzed data 330...
Cancer of the oral cavity and oropharynx is a major public health problem in Spain. Tobacco alcohol have been identified as two risk factors for cancer most western populations. Other include diets low fruits vegetables, but impact dietary habits on these cancers has never assessed The objective this study was to elucidate role oropharyngeal cancer, multicentric case–control conducted three areas Spain (Barcelona, Granada Sevilla) between 1996 1999. Cases were 375 patients (71 women), with...
Purpose To compare the safety and efficacy of a new enhanced viscosity ophthalmic formulation tobramycin, given twice daily (BID), with existing four times (QID) treatment regimen in patients acute bacterial conjunctivitis. Methods This was 12-day, multicenter, observer-masked, randomized, parallel group study. Patients received one drop tobramycin 0.3% (3 mg/mL) solution BID or QID affected eyes for 7 days. The primary variable percentage sustained cure/presumed eradication based on...
Abstract Background Post-extubation upper airway obstruction (UAO) is a frequent complication causing stridor and respiratory distress, which occasionally require reintubation, thereby increasing morbidity mortality rates. Contradictory results have been obtained in studies assessing the effectiveness of steroids preventing post-extubation UAO, available evidence limited. We designed multicentric randomized, placebo-controlled study to explore dexamethasone UAO children. Methods A...
<b>Background:</b> Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and irreversible form of fibrotic intersticial lung disease, characterized by uncontrolled fibroblast proliferative processes alveolar type II epithelial dysfunction. MUC1 considered as oncogenic molecule altering signaling pathways involved in cellular proliferation cell death. <b>Objective:</b> To analyze the implication IPF <b>Methods:</b> Lung tissue from 14 healthy patients was obtained. The expression...
<h3>Background</h3> Angiodysplasia (AD) is the most common vascular malformation of gastrointestinal (GI) tract and causes significant morbidity. Long-acting octreotide, administered intramuscularly once per month might be useful for controlling chronic bleeding from angiodysplasia as an off-label use. Some case reports have demonstrated a benefit. <h3>Purpose</h3> To evaluate effectiveness safety long-acting octreotide use in patients suffering GI AD. <h3>Material methods</h3> A...
<h3>Background</h3> According to the Institute of Medicine, inadequate medication labelling accounts for 33% errors. As part institutional risk management strategy, in 2015 a multidisciplinary team redesigned labels hospital compounded preparations order comply with recommendations issued by Safe Medication Practices and include route administration colour coding. <h3>Purpose</h3> To develop computer test label design testing. compare previous new assessing probability data misinterpretation...
<h3>Background</h3> In order to adapt Spanish regulations the principles set out in European Resolution CM/ResAP(2011)1 on quality and safety assurance requirements for medicinal products prepared pharmacies, a guideline pharmacy sterile preparations at hospital pharmacies (GPSP) was published by Ministry of Health June 2014. The includes risk based decision matrix determine potential microbial contamination (PSPs) sets beyond use dates (BUDs). According GPSP requirements, if recommended BUD...
<h3>Background</h3> Long term adverse effects, expense and difficulty of adherence to antiretroviral therapy (ART) have led the study simpler maintenance therapies. Switching from triple dual seems be effective safe, but few data exist in clinical practice. <h3>Purpose</h3> To assess effectiveness safety simplification a experienced HIV patients. <h3>Material methods</h3> A retrospective including patients switching between August 2009 January 2015. Demographic characteristics, viral load...
Case: we present a patient with alveolar hemorrhage associated tirofiban, whose diagnosis was delayed because the initial signs, which were misinterpreted as pneumonia, unrecognized. Discussion and conclusions: an early accurate is essential to guide appropriate management of any type bleeding complication in acute coronary syndrome (ACS), especially case (AH).
<h3>Background</h3> Hereditary haemorrhagic telangiectasia (HHT), also known as Osler–Weber–Rendu disease, is a rare, vascular, autosomal dominant disorder. Telangiectasias and arteriovenous malformations (AVMs) of the lung, liver CNS are vascular lesions present in HHT, most commonly causing epistaxis gastrointestinal bleeding. The diagnosis based on Curaçao criteria. Recently, severity score (ESS) was created standardised measure to estimate degree epistaxis. <h3>Purpose</h3> To describe...
Abstract Background Post-extubation upper airway obstruction (UAO) is a frequent complication causing stridor and respiratory distress, which occasionally may require reintubation, thereby increasing morbidity mortality rates. Contradictory results have been obtained in studies assessing the effectiveness of steroids preventing post-extubation UAO, available evidence limited. We designed multicentric randomized, placebo-controlled study to explore dexamethasone UAO children. Methods A...
Abstract Background: Post-extubation upper airway obstruction (UAO) is a frequent complication causing stridor and respiratory distress, which occasionally may require reintubation, thereby increasing morbidity mortality rates. Contradictory results have been obtained in studies assessing the effectiveness of steroids preventing post-extubation UAO, available evidence limited. We designed multicentric randomized, placebo-controlled study to explore dexamethasone UAO children. Methods: A...