Lixue Yin

ORCID: 0000-0003-3758-4313
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About
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Research Areas
  • Cardiovascular Function and Risk Factors
  • Cardiac Imaging and Diagnostics
  • Cardiomyopathy and Myosin Studies
  • Congenital Heart Disease Studies
  • Cardiac Valve Diseases and Treatments
  • Cardiac Arrhythmias and Treatments
  • Cardiovascular Health and Disease Prevention
  • Cardiac electrophysiology and arrhythmias
  • Medical Image Segmentation Techniques
  • Atrial Fibrillation Management and Outcomes
  • Cardiac pacing and defibrillation studies
  • Cardiovascular and Diving-Related Complications
  • AI in cancer detection
  • Acute Ischemic Stroke Management
  • Adipokines, Inflammation, and Metabolic Diseases
  • Cardiovascular Effects of Exercise
  • Cardiovascular Disease and Adiposity
  • Blood Pressure and Hypertension Studies
  • Berberine and alkaloids research
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiovascular and exercise physiology
  • COVID-19 and healthcare impacts
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Inflammatory Biomarkers in Disease Prognosis
  • Thyroid Cancer Diagnosis and Treatment

University of Electronic Science and Technology of China
2017-2025

Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
2015-2025

Maternal and Child Health Hospital of Sichuan Province
2024

Chinese Academy of Sciences
2023

Southwest Petroleum University
2023

Hangzhou First People's Hospital
2020

Shandong Chest Hospital
2016

Qilu Hospital of Shandong University
2016

Sichuan Provincial Hospital of Traditional Chinese Medicine
2003

Abstract Background Lipid and inflammatory molecules play a key role in the development of inflammation. Neutrophil counts are used as markers inflammation duration, HDL-C is an anti-atherosclerosis component. However, few studies have been found to integrate these two indicators explore coronary stenosis. We suggested that neutrophil count marker persistence anti-atherosclerotic component should be integrated into single biomarker NHR its correlation with CAD degree predict severity...

10.1186/s12872-020-01771-z article EN cc-by BMC Cardiovascular Disorders 2021-03-06

Abstract Objective This study aims to investigate the characteristics of myocardial work(MW) and reserve function in left ventricular remodeling hypertension (LVRH) patients through exercise stress echocardiography (ESE) pressure-strain loop (PSL) technique,and further associations MW parameters with capacity this observational study. Methods One hundred five hypertensive remodeling{Left mass index (LVMI) ≥115 g/m2 (male) LVMI ≥95 (female)} underwent ESE examination according established...

10.1093/ehjci/jeae333.327 article EN European Heart Journal - Cardiovascular Imaging 2025-01-01

ABSTRACT Purpose This study aims to elucidate the characteristics of segment myocardial work (MW) and reserve function through exercise stress echocardiography (ESE) explore associations between MW parameters capacity in patients with left ventricular remodeling due hypertension (LVRH). Methods A total 105 LVRH (LVMI ≥ 115 g/m 2 for males LVMI 95 females) underwent ESE examination following established guidelines. Additionally, 59 healthy subjects served as a control group. Speckle tracking...

10.1111/echo.70093 article EN Echocardiography 2025-03-01

This study aimed to investigate the clinical implications of vascular aging (VAg) phenotypes based on difference between chronological age (CA) and (VA). We defined VA as predicted in a multivariable linear regression model including structural functional parameters arteries conventional risk factors, multicentric, cross-sectional cohort (n=15580). According 10th 90th percentiles Δ-age (CA minus VA), we then classified status VAg into 3 phenotypes: early (EVA), Normal supernormal...

10.2147/cia.s485597 article EN cc-by-nc Clinical Interventions in Aging 2025-03-01

ABSTRACT Objective This study aimed to assess the impact of ventricular septal defect (VSD) on fetal cardiac geometry and systolic function during second trimester using Fetal Heart Quantification (Fetal HQ) technology. Methods In this prospective study, 91 fetuses with isolated VSD gestational age‐matched healthy controls were evaluated. Using GE Voluson E10 ultrasound system HQ software, parameters such as global sphericity index (GSI), longitudinal strain (GLS), ejection fraction (EF),...

10.1002/pd.6783 article EN cc-by-nc Prenatal Diagnosis 2025-04-01

AimsCurrently, available Doppler echocardiographic reference values are derived mainly from North American and European population studies, which may not applicable to the Chinese population. We aimed establish normal of parameters in a nationwide, population-based cohort healthy Han adults.

10.1093/ehjci/jev330 article EN European Heart Journal - Cardiovascular Imaging 2015-12-28

Inflammation and lipid signaling are involved in the pathogenesis progression of coronary artery disease (CAD). We proposed that high-sensitivity C-reactive proteins, as a marker pro-inflammatory state, high-density lipoprotein cholesterol (HDL-C), an anti-atherosclerosis component, should be integrated into single novel biomarker. Our work was conducted to discuss compare predictive ability protein ratio (CHR) with other existing indices, for example, neutrophil (NHR) lymphocyte (NLR),...

10.1536/ihj.21-246 article EN International Heart Journal 2021-11-05

Abstract Background Atrial fibrillation (AF) is associated with an increased risk of dementia. Little known about the relationship antithrombotic therapy and dementia in patients AF without clinical stroke. Method This was observational study based on a hospital registry. Patients aged 65–85 years at time diagnosis were identified via computerised database management system. prior stroke or cognitive dysfunction excluded. The primary outcome newly diagnosed during follow-up period. Results...

10.1136/postgradmedj-2020-137916 article EN Postgraduate Medical Journal 2020-11-12

Heart failure (HF) increases the risk of thromboembolic events (TE). Study in a Caucasian population has shown that CHA2DS2-VASc score predicts TE among HF patients without atrial fibrillation. We sought to assess usefulness predicting an Asian and refine scoring system improve its predictability sinus rhythm.A total 1,202 consecutive who were admitted our institution for new-onset from 2005 2012 fibrillation or anticoagulation retrospectively reviewed.The mean age was 77.6 ± 12.2 years...

10.1371/journal.pone.0169095 article EN cc-by PLoS ONE 2016-12-30

Background Inhibition of Rho/ROCK signalling pathway related proteins can alleviate left ventricular hypertrophy. Berberine hydrochloride (BBR) effectively inhibit The purpose this study is to explore the relationship between BBR and pathway.Methods Isoproterenol (ISO) was used induce hypertrophy in rats. Two-dimensional speckle tracking technique (2D-STE) evaluate rats each group (group A: normal control group; Group B: isoproterenol model C: ISO + 5mg/kg D: 10mg/kg group) Heart structure...

10.1080/00015385.2023.2168876 article EN cc-by-nc-nd Acta Cardiologica 2023-02-28

Objectives: To assess the performance of elastography (ES) and ultrasound (US) in predicting malignancy breast lesions to compare their combined diagnostic value with that magnetic resonance imaging (MRI). Materials Methods: The study prospectively enrolled 242 female patients dense breasts treated 35 heath care facilities China between November 2018 October 2019. Based on conventional US elastography, radiologists classified degree suspicion according Breast Imaging Reporting Data System...

10.7150/jca.43326 article EN cc-by-nc Journal of Cancer 2020-01-01

Objective The aim of this study was to evaluate the clinical significance remote consultation over bedside transthoracic echocardiography (RC-B-TTE) for patients with coronavirus disease 2019 (COVID-19). Methods Five frontline echocardiographers performed and interpreted B-TTE 30 COVID-19 in isolation wards, on-site reports (OSR) were generated. Then studies conducted by two experienced echocardiographic consultants while blinded OSR, corresponding (RCR) Subsequently, five convened together...

10.1111/echo.15124 article EN Echocardiography 2021-05-31

The aim of this study is to evaluate the left atrial strain (LAS) in patients with hypertrophic cardiomyopathy (HCM) by treadmill exercise stress echocardiography, combined three-dimensional speckle tracking technology, for predicting tolerance.A total 97 HCM who underwent echocardiography were recruited Sichuan Provincial People's Hospital between January 2018 and 2021, 30 control subjects selected be included normal group. their metabolic equivalents (METS) ≤ 6.0 HCM-1 group, while those...

10.3389/fcvm.2023.1168514 article EN cc-by Frontiers in Cardiovascular Medicine 2023-05-15

Carotid atherosclerosis plaque rupture is an important cause of myocardial infarction and stroke. The effective segmentation ultrasound images carotid atherosclerotic plaques aids clinicians to accurately assess stability. At present, this procedure relies mainly on the experience medical practitioner manually segment image plaque. This method also time-consuming.This study intends establish automatic intelligent plaque.The present combined U-Net DenseNet networks, automatically plaques....

10.3233/thc-220152 article EN Technology and Health Care 2022-08-09

Abstract Purpose The aim of this study was to investigate myocardial dysfunction and mechanical abnormalities in young patients with Graves' disease before therapy, using two‐dimensional speckle tracking echocardiography. Methods We performed a comprehensive transthoracic echocardiographic examination, including segmental global radial strain, time‐to‐peak 47 hyperthyroidism 34 healthy adults. strain corrected by RR interval. variables derived from deformation the six‐basal, six‐mid,...

10.1002/jcu.22802 article EN Journal of Clinical Ultrasound 2019-12-13

The aim of this prospective study was to assess the diagnosis value four-dimensional echocardiography area strain (AS) combined with exercise stress evaluate left ventricular regional systolic function in patients mild single vessel coronary artery stenosis.Based on treadmill load status, two-dimensional conventional and were performed suspected disease before angiogram. Thirty (case group) anterior descending stenosis (stenosis <50%) thirty gender- age-matched (control without according...

10.1111/echo.13638 article EN Echocardiography 2017-07-28
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