- Natural Products and Biological Research
- Veterinary medicine and infectious diseases
- Plant Virus Research Studies
- Viral-associated cancers and disorders
- Berry genetics and cultivation research
- Health and Wellbeing Research
- Diverse Approaches in Healthcare and Education Studies
- Cervical Cancer and HPV Research
- Soybean genetics and cultivation
- Wheat and Barley Genetics and Pathology
- Agricultural Practices and Plant Genetics
- Sugarcane Cultivation and Processing
- Plant Pathogenic Bacteria Studies
- Plant Genetic and Mutation Studies
- Plant Disease Resistance and Genetics
- Ovarian cancer diagnosis and treatment
- Genetic Mapping and Diversity in Plants and Animals
- Cytomegalovirus and herpesvirus research
- Lymphoma Diagnosis and Treatment
- Lipid metabolism and biosynthesis
- RNA regulation and disease
- Biological and pharmacological studies of plants
- Polyomavirus and related diseases
- Hypothalamic control of reproductive hormones
- Chromatography in Natural Products
Seeders (South Korea)
2014-2023
University of Wisconsin–Madison
2016-2022
Daeduk University
2016-2018
Gyeongsang National University
2000-2015
Jacobson Holman (United States)
2015
Ewha Womans University
2008-2010
Korea Research Institute of Bioscience and Biotechnology
2005
The tomato (Solanum lycopersicum L.) is a model plant for genome research in Solanaceae, as well studying crop breeding.Genome-wide single nucleotide polymorphisms (SNPs) are valuable resource genetic and breeding.However, to do discovery of genome-wide SNPs, most methods require expensive high-depth sequencing.Here, we describe method SNP calling using modified version SAMtools that improved its sensitivity.We analyzed 90 Gb raw sequence data from nextgeneration sequencing two resequencing...
Langerhans cell sarcoma (LCS) is a neoplastic proliferation of cells that have overtly malignant cytologic features. It very rare disease and theoretically, it can present de novo or progress from an antecedent histiocytosis (LCH). However, to our knowledge, LCS arising LCH has not been reported on. We here case pulmonary LCH. A 34 yr-old man who was smoker, had fever chronic cough. Computed tomographic (CT) scan revealed multiple tiny nodules in both lungs. The thoracoscopic lung biopsy...
Systemic activation of hemostasis and thrombosis has been implicated in tumor progression metastasis. D-dimer used as an indicator for the thrombosis. Here, we investigated role coagulation patients with metastatic gastric cancer by measuring level. We conducted observation study 46 who received palliative chemotherapy (CTx). levels were assessed before CTx at first response evaluation after CTx. The overall survival (OS) pretreatment <1.5 μg/mL was significantly longer than that ≥1.5 (22.0...
The UL133-138 locus present in clinical strains of human cytomegalovirus (HCMV) encodes proteins required for latency and reactivation CD34(+) hematopoietic progenitor cells virion maturation endothelial cells. encoded form multiple homo- hetero-interactions localize within secretory membranes. One these genes, UL136 gene, is expressed as at least five different protein isoforms with overlapping unique functions. Here we show that another gene from this locus, the UL138 also generates more...
The purpose of this study is to investigate differences in organ-specific cancer incidence according the region and population size Korea.We reviewed data registration program Gyeongnam Regional Cancer Center between 2008 2011. Age-standardized rates were analyzed administrative zone.Incidence thyroid has been increasing rapidly both urban rural areas. However, was much lower areas than megalopolis such as Seoul. Gastric relatively more common areas, near sea (Ulsan, Busan, Incheon), other...
Rubus is an economically important fruit crop across the globe. Recently, several mutant genotypes with improved agronomic traits have been developed using gamma ray irradiation. This study investigated genetic diversity and variations in single nucleotide polymorphism (SNP) markers generated from genotyping-by-sequencing (GBS) analysis. A GBS library of 14 genotypes, consisting seven boysenberry lines, four blackberry three original varieties, were sequenced on Illumina Hiseq2000 platform....
Subcutaneous panniculitis-like T cell lymphoma (SPTL) is a distinctive cutaneous characterized by an infiltration of subcutaneous tissue neoplastic cells, similar to panniculitis. It well-established that patients who are diagnosed with SPTL usually respond poorly chemotherapy, showing fatal outcome. As first line treatment for SPTL, anthracycline-based chemotherapy was most frequently used. For the efficacy cyclosporine A has been recently reported in relapsed after chemotherapy. However,...
Replication-dependent (RD) histones are deposited onto human cytomegalovirus (HCMV) genomes at the start of infection. We examined how HCMV affects de novo production RD and found that viral infection blocked accumulation histone mRNAs normally occurs during S phase. Furthermore, present in HCMV-infected cells did not undergo unique 3′ processing required for their normal nuclear export translation. The protein orchestrates nucleus, stem loop–binding (SLBP), was predominantly cytoplasm,...
In this study, gene expression changes in cowpea plants irradiated by two different types of radiation: proton-beams and gamma-rays were investigated. Seeds the Okdang cultivar exposed to 100, 200, 300 Gy proton-beams. transcriptome analysis, 32, 75, 69 differentially expressed genes (DEGs) at each dose gamma-ray irradiation compared with that control identified. A total eight commonly up-regulated for all doses. However, there no down-regulated genes. contrast, 168, 434, 387 DEGs identified...
Perilla citriodora is a diploid and an aromatic herb species belonging to the family Lamiaceae widely distributed in East Asia. The complete chloroplast genome sequence of P. was generated by de novo assembly using whole next-generation sequences. assembled 152 588 bp length structurally divided into four distinct regions; large single copy region (83 699 bp), small (17 537 pair inverted repeat regions (25 676 bp). A total 115 genes were annotated including 81 protein-coding genes, 30 tRNA...
Perilla is a key component of Korean food. It contains several plant-specialized metabolites that provide medical benefits. In response to an increased interest in healthy supplement food from the public, people are focusing on properties Perilla. Nevertheless, unlike rice and soybeans, there few studies based molecular genetics Perilla, so it difficult systematically study breed. The wild citriodora 'Jeju17', was identified decade ago island Jeju. Using short-reads, long-reads, Hi-C,...
The coexistence of aspergillosis and squamous cell carcinoma (SCC) in the maxillary sinus was very rare. To our knowledge, this is second report coexistent SCC sinus. A 58-year-old man underwent surgery for unilateral infection with oroantral fistula. In surgical specimen, were co-detected routine immunohistochemical stainings. Moreover, human papillomavirus 18 (HPV-18) detected by polymerase chain reaction specimen. patient re-operated subtotal maxillectomy has been followed up two years...
This report describes methods for selecting informative single nucleotide polymorphisms (SNPs), and the development of an online Solanaceae genome database, using 234 tomato resequencing data entries deposited in NCBI SRA database.The 126 accessions Solanum lycopersicum, 68 lycopersicum var.cerasiforme, 33 pimpinellifolium, which are frequently used breeding, some wild-species were included analysis.To select tag-SNPs, we identified 29,504,960 SNPs tomatoes then separated genic intergenic...
이 연구는 수도권 66개 시·군·구를 대상으로 도시간 인구이동 결정요인을 분석한다. 전출지와 전입지를 하나의 쌍으로 하는 자료를 구축하며 도시 내부 인구이동은 제외한다. 종속변수로 인구 전입률을 설정하며 결정요인으로 인구지표, 거리지표, 주택지표, 경제지표, 도시기반시설지표를 사용한다. 분석 결과는 다음과 같다. 첫째, 전입지 간의 거리가 멀수록 인구이동이 감소하며 둘째, 2000년 이후 택지개발사업으로 전출지의 주택이 증가하거나 자가 APT 비율이 증가할 경우 전입지의 감소시키는 것으로 나타났다. 본 기존 연구와 달리 전입지와 전출지를 동시에 고려한 모형을 구축하고 연구를 수행했다는 점에서 의의가 있다.