A5101509571- Reproductive Biology and Fertility
- Plant-Microbe Interactions and Immunity
- Ovarian function and disorders
- Legume Nitrogen Fixing Symbiosis
- Mycorrhizal Fungi and Plant Interactions
- Fungal Biology and Applications
- Plant Pathogens and Fungal Diseases
- Plant nutrient uptake and metabolism
- Endometriosis Research and Treatment
- Plant Pathogenic Bacteria Studies
- Plant Micronutrient Interactions and Effects
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Health and Technologies
- Plant Disease Resistance and Genetics
- Forest Ecology and Biodiversity Studies
- Plant Parasitism and Resistance
- Plant Molecular Biology Research
- Cerebrovascular and Carotid Artery Diseases
- Nitrogen and Sulfur Effects on Brassica
- Plant Gene Expression Analysis
- Fungal and yeast genetics research
- Plant Stress Responses and Tolerance
- Reproductive System and Pregnancy
- Research in Cotton Cultivation
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Northwest A&F University
2022-2025
State Grid Corporation of China (China)
2025
Lanzhou University of Technology
2020-2024
University of Cologne
2021-2023
Wageningen University & Research
2019-2022
Shanghai East Hospital
2018-2022
Peking University People's Hospital
2022
Peking University
2022
Cluster of Excellence on Plant Sciences
2021
Lanzhou University
2020
Objective To investigate the clinical outcome and endocrinological characteristics of progestin‐primed ovarian stimulation ( PPOS ) using 4 versus 10 mg medroxyprogesterone acetate MPA per day in infertile women with normal ovary reserve. Design A randomised parallel controlled trial. Setting Tertiary‐care academic medical centre. Participants cohort 300 undergoing vitro fertilisation IVF )/intracytoplasmic sperm injection ICSI treatment. Methods Human menopausal gonadotropin hMG ; 225 iu...
We have previously reported a new luteal-phase ovarian stimulation (LPS) strategy for infertility treatment. The purpose of this study was to systematically assess the efficiency and safety by comparing it with conventional protocols.Retrospective cohort study.Patients normal reserve undergoing ovum pick-up (OPU) cycles between April 2012 September 2013 were enrolled: 708 patients underwent LPS protocol compared 745 who mild treatment 1287 short-term protocol.Number mature oocytes retrieved...
Plants trigger immune responses upon recognition of fungal cell wall chitin, followed by the release various antimicrobials, including chitinase enzymes that hydrolyze chitin. In turn, many pathogens secrete LysM effectors prevent chitin host through scavenging oligomers. We previously showed intrachain dimerization Cladosporium fulvum effector Ecp6 confers an ultrahigh-affinity binding groove competitively sequesters oligomers from receptors. Additionally, particular are found to protect...
ObjectiveTo investigate flexibility in starting controlled ovarian stimulation at any phase of the menstrual cycle infertile women undergoing treatment with assisted reproduction.DesignRetrospective cohort study.SettingAcademic tertiary-care medical center.Patient(s)At total 150 patients vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) treatment. Ninety also underwent frozen embryo transfer (FET) procedures.Intervention(s)Depending on when was started, three groups were...
During fungal infections, plant cells secrete chitinases, which digest chitin in the cell walls. The recognition of released oligomers via lysin motif (LysM)-containing immune host receptors results activation defense signaling pathways. We report here that Verticillium nonalfalfae, a hemibiotrophic xylem-invading fungus, prevents these digestion and processes by secreting carbohydrate-binding 18 (CBM18)-chitin-binding protein, VnaChtBP, is transcriptionally activated specifically during...
Abstract Chitin is a major structural component of fungal cell walls and acts as microbe‐associated molecular pattern (MAMP) that, on recognition by plant host, triggers the activation immune responses. To avoid these responses, Septoria tritici blotch (STB) pathogen wheat, Zymoseptoria , secretes LysM effector proteins. Previously, effectors Mg1LysM Mg3LysM were shown to protect hyphae against host chitinases. Furthermore, Mg3LysM, but not Mg1LysM, was suppress chitin‐induced reactive...
Abstract Arbuscular mycorrhizal (AM) fungi may have some potential use in the restoration of degraded grassland through beneficial effects on plant growth and soil quality. A field investigation was conducted three sites typical steppe Inner Mongolia. The communities, one which undegraded, moderately third severely degraded, were studied by collecting samples four species that occurred all sites. percentage root length colonized AM estimated composition diversity fungus spores recovered from...
Abstract Chitin is a homopolymer of β-(1,4)-linked N-acetyl-D-glucosamine (GlcNAc) and major structural component fungal cell walls. In plants, chitin acts as microbe-associated molecular pattern (MAMP) that recognized by lysin motif (LysM)-containing plant surface-localized recognition receptors (PRRs) activate plethora downstream immune responses. To deregulate chitin-induced immunity successfully establish infection, many pathogens secrete LysM domain-containing effector proteins during...
Abstract Plant‐pathogenic fungi are causative agents of the majority plant diseases and can lead to severe crop loss in infected populations. Fungal colonization is achieved by combining different strategies, such as avoiding counteracting immune system manipulating host metabolome. Of major importance virulence factors secreted fungi, which fulfil diverse functions support infection process. Most these proteins highly specialized, with structural biochemical information often absent. Here,...
Endometriosis, the presence of active endometrial tissue outside lining membrane uterine cavity, is a common disease in women childbearing age. The ectopic endometrium has some characteristics tumor tissue, including invasive and migratory abilities. In addition, endometriosis associated with inflammation reduced cellular apoptosis.Western blot analysis, qPCR, immunohistochemistry, immunofluorescence microscopy, Transwell assay, wound healing TUNEL staining.Interleukin-1β (IL-1β) induced...
Polycystic ovary syndrome (PCOS) is an endocrinopathy with complex pathophysiology that a common cause of anovulatory infertility in women. Although the disruption circadian rhythms indicated PCOS, role clock etiology these pathologies has yet to be appreciated. The nuclear receptors REV-ERBα and REV-ERBβ are core modulators participate regulation diverse set biological functions. However, expression REV-ERBs their effects remain unclear. Here, we demonstrate levels were lower granulosa...
During the storage and processing time of lily bulb, violet‐red discoloration scales often occurs, which is mainly caused by biosynthesis anthocyanin. To investigate effect light irradiation on accumulation anthocyanin in fresh‐cut bulb scales, here, we examined 12 days shading at 20°C We found that color change treated with 20°C/light was greater than subjected to 20°C/shading treatment. This difference based variations L ∗ , a b values, as well degree browning surface scales. The content...
Oral progestin has recently been used to prevent premature LH surges in ovarian stimulation, and this progestin-primed stimulation (PPOS) is effective safe patients with different reserves. The current data are lacking regarding how individualize the gonadotropin dose regimen for women polycystic syndrome (PCOS). A retrospective cohort trial was performed evaluate efficacy of milder clomiphene citrate (CC) compared standard protocol infertile PCOS. total 220 PCOS were collected classified...
Abstract The potential effects of high basal luteinizing hormone (LH) levels on human reproduction were controversial. To demonstrate the elevated LH outcome patients undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles, we performed a retrospective data analysis 1011 polycystic ovarian syndrome (PCOS) treated with menopausal gonadotropin and medroxyprogesterone acetate (hMG + MPA) protocol at our center between Nov. 2013 Jun. 2017. PCOS had significantly...
Abstract Context The LH/chorionic gonadotropin receptor (LHCGR) is mainly expressed in gonads and plays important roles estradiol production, ovulation, luteal formation. Women with pathogenic LHCGR variants suffer from infertility, successful fertility treatments for such women have never been reported. Objective purpose of this study was to determine whether can achieve pregnancies through vitro fertilization. Design Three LH resistance infertility their parents underwent exome sequencing....
Premature ovulation occurs at a high rate in natural-cycle vitro fertilization (IVF), and cycle cancellation further hampers the overall efficiency of procedure. While lower levels estradiol (E2) are observed preovulatory follicles, it is unclear whether declines E2 can be used as an effective marker premature ovulation.This retrospective analysis includes 801 natural/unstimulated IVF/ICSI cycles undergoing scheduled ovum pick-up (OPU) 153 emergency OPU university IVF center from May 2014 to...