A5026014319- Streptococcal Infections and Treatments
- Antifungal resistance and susceptibility
- Antimicrobial Resistance in Staphylococcus
- COVID-19 Clinical Research Studies
- Respiratory viral infections research
- Bacterial Identification and Susceptibility Testing
- Neutropenia and Cancer Infections
- Fungal Infections and Studies
- Pneumonia and Respiratory Infections
- Kawasaki Disease and Coronary Complications
- Antibiotic Use and Resistance
- Urinary Tract Infections Management
- Pediatric Urology and Nephrology Studies
- Infective Endocarditis Diagnosis and Management
- Antibiotics Pharmacokinetics and Efficacy
- Nosocomial Infections in ICU
- Bacterial Infections and Vaccines
- COVID-19 and Mental Health
- Blood disorders and treatments
- Neonatal and Maternal Infections
- COVID-19 and healthcare impacts
- Emotional Intelligence and Performance
- Neonatal Health and Biochemistry
- Infectious Encephalopathies and Encephalitis
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Hospital Roberto del Rio
2008-2025
Universidad Abierta Interamericana
2025
University of Chile
2008-2021
Sociedad de Biología de Chile
2016-2021
Hospital Luis Calvo Mackenna
2008
To compare the efficacy of pre-emptive versus empirical antifungal therapy in children with cancer, fever and neutropenia. This was a prospective, multicentre, randomized clinical trial. Children presenting persistent high-risk febrile neutropenia at five hospitals Santiago, Chile, were to or therapy. The group received only if accompanied by clinical, laboratory, imaging microbiological pre-defined criteria. primary endpoint overall mortality day 30 follow-up. Secondary endpoints included...
The new SARS-CoV-2 coronavirus or Coronavirus Disease 2019 (COVID-19) emerged in Wuhan, China and was officially declared as the source of pandemic March 2020 by World Health Organization (WHO). Its impact on nursing significant it caused numerous stressors staff working front line care. imposed conditions nurses, which impacted personal work-related issues that were interrelated with quality health care.The present study aimed to determine presence Job Stress primary care professionals...
Abstract Background Antimicrobial resistance (AMR) is a global concern. Collecting data and implementing interventions to optimize antimicrobial (AM) use has significant potential lower AMR.There no information in Latin American Region on how prescribers are using from positive blood culture results de-escalate AM. We present sub-analysis of the 2022-2023 Latin-PPS performed Chile including characterization bacteriemia de-escalation practices. distribution treat bacteremia Methods 13 public...
Abstract Background Clesrovimab is an investigational, long-acting monoclonal antibody for the prevention of RSV lower respiratory tract infection (LRI) in infants, including those at high risk severe disease due to serious comorbidity or premature birth. Methods This a planned interim analysis (IA) randomized, controlled, phase 3 trial infants entering their first season recommended receive palivizumab prematurity (≤35 weeks gestational age), chronic lung (CLD) prematurity, hemodynamically...
Background: Accurate diagnosis of catheter-related blood stream infection (CRBSI) is necessary to make a decision about removal the catheter. Differential time positivity (DTP) and ratio quantitative cultures (RQC) between central peripheral have not been evaluated against strict standard in children, namely catheter tip culture. Objective: Our aim compare DTP RQC tip-confirmed children. Method: Prospective study performed 2 large hospitals Santiago, Chile. Children with clinically suspected...
Abstract Background Central nervous system (CNS) infection has been an ongoing concern in paediatrics. The FilmArray® Meningoencephalitis (FAME) panel greater sensitivity identifying the aetiology of CNS infections. This study’s objective was to compare aetiological identification and hospitalization costs among patients with suspected before after use FAME. Methods An analytical observational study carried out using a retrospective cohort for pre-intervention (pre-FAME use) period...
Community associated-methicillin-resistant Staphylococcus aureus (SAMR-AC): comunication of the first four pediatric cases in Roberto del Rio Children´s HospitalStaphylococcus is a known pathogen patients that produces skin infections, cutaneous abscess, cellulitis and osteoarticular infections.Most these infections are produced by meticilin susceptible strain.The community associated methicillin resistant was published for time 1993, ever since then has been recognized as cosmopolite...
Chilean consensus of prevention, diagnosis and treatment ofClostridium difficile-associated diarrhea
Microorganisms isolated from blood cultures (BC) in patients with febrile neutropenia (NF) vary over time, requiring systematic monitoring to guide appropriate empirical therapy.To identify microorganisms BC and their antimicrobial resistance profile children cancer high risk NF.Prospective, multicenter study. The analysis included episodes of high-risk FN positive under 18 years age treated five hospitals Santiago, Chile, 2012-2015.A total 206 were analyzed 185 FN. main isolates Gram...
Several risk factors are associated with COVID-19 severity and death, such as advanced age, male sex, the presence of comorbidities.To study effect these socioeconomic variables on outcome Chilean patients admitted to a public hospital.Review medical records hospital positive PCR test for COVID-19, Chile from March June 2020. The variable was (ICU admission or death). exposure were level, comorbidities. A multivariable logistic regression analysis performed.Of 1,141 confirmed cases, 266...
Risk factor of intestinal colonization with vancomycin resistant Enterococcus spp in hospitalized pediatric patients oncological diseaseBackground: The isolation vancomycin-resistant (ERV) has increased significantly within the last few years, along risk infection and dissemination these bacteria.Our aim was to determine factors (RF) for disease at Hospital de Niños Roberto del Río.Methods: Between January 2012 December 2013 a transversal study performed 107 rectal swabs processed PCR...
Aspergillus fumigatus mediastinitis in an immunocompetent pediatric patient after heart surgeryPostsurgical aspergillosis occurs primarily patients whose main predisposing factor is the loss of skin and mucosal integrity during surgery.Local infection tends to be destructive refractory treatment relapses are common.It important consider differential diagnosis slowly progressive surgical site infections with negative bacterial cultures.We present case a child who developed months surgery.
Enterobacteriaceae are a group of gram-negative rods that can cause serious infections in humans. A susceptibility Klebsiella pneumoniae 79.4% to piperacillin/tazobactam (PIP/TAZO) is reported pediatric hospitals Chile. There no published data date regarding PIP/TAZO other species this population.To measure the vitro isolates from patients hospital Chile.Descriptive and prospective study positive cultures assisting "Hospital de niños Roberto del Río" (HRRIO) between January 2013 August 2014....
Staphylococcus aureus coloniza la nasofaringe en un tercio de los individuos sanos y además es causante infecciones graves pediatría, como endocarditis, neumonía e osteoarticulares. Posee varios mecanismos virulencia, siendo leucocidina Panton Valentine (LPV) uno ellos, una exotoxina que causa muerte celular. Su producción está comúnmente relacionada con resistente a meticilina (SARM) pulmonares musculo-esqueléticas graves. Sin embargo, LPV no exclusiva SARM. Se presentan dos casos clínicos...
La infección del tracto urinario (ITU) es una de las infecciones bacterianas más frecuentes en la infancia. Un adecuado diagnóstico esencial para poder realizar un tratamiento racional, eficiente y eficaz; sin embargo, existe gran heterogeneidad los métodos diagnósticos, especÃficamente el estudio susceptibilidad antimicrobiana. El objetivo estas recomendaciones entregar herramientas uniformar criterios bacteriana in vitro antimicrobiano ITU población pediátrica, con enfoque uso...