A5102842720- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Long-Term Effects of COVID-19
- Renal and Vascular Pathologies
- COVID-19 Clinical Research Studies
- Congenital Heart Disease Studies
- Venous Thromboembolism Diagnosis and Management
- Intracranial Aneurysms: Treatment and Complications
- Cerebral Venous Sinus Thrombosis
- Cardiovascular and Diving-Related Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Peripheral Neuropathies and Disorders
- Infectious Encephalopathies and Encephalitis
- COVID-19 and healthcare impacts
- Cerebrovascular and genetic disorders
- Clinical practice guidelines implementation
- Alcoholism and Thiamine Deficiency
- Cardiovascular Health and Disease Prevention
- Neurobiology of Language and Bilingualism
- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- Memory and Neural Mechanisms
- Multiple Sclerosis Research Studies
- ECG Monitoring and Analysis
- Trauma and Emergency Care Studies
Emory University
2020-2025
University of Iowa
2024-2025
University of Iowa Hospitals and Clinics
2023-2024
University of Pittsburgh
2024
University of Washington
2024
University of Thessaly
2024
Grady Memorial Hospital
2022-2023
Emory University Hospital
2022
University of Minnesota
2020
Background: The term embolic stroke of undetermined source (ESUS) encompasses a substantial but heterogeneous population patients with ischemic stroke, underscoring the importance identifying personalized treatment strategies. In subgroups randomized in ESUS trials, we evaluated effectiveness anticoagulation compared to antiplatelet therapy secondary prevention. Methods: A study-level meta-analysis was conducted controlled trials ESUS, comparing therapy. primary efficacy outcome recurrent...
Introduction: Atrial Fibrillation (AF) is detected in nearly 30% of patients undergoing cardiac monitoring after ischemic stroke. Studies investigating predictors AF showed mixed results. In this study, we aim to identify on insertable monitors (ICMs) and compare rates between cryptogenic stroke controls. Methods: The ANT icoagulation A nd St R oke Re C urrence T rial F I brillation Dete ted fter Stroke (ANTARCTICA) study an individual patient data meta-analysis prospective observational...
Background Recent randomized clinical trials have demonstrated that endovascular therapy for basilar artery occlusion is safe and potentially effective, predominantly in the non‐White population. The aim of this study was to identify predictors good functional outcome posterior circulation strokes US population after mechanical thrombectomy from TRACK (Trevo Stent‐Retriever Acute Stroke) NASA (North American Solitaire Stent Retriever registries North America. Methods Patient‐level data were...
Screening scales are recommended to assist field-based triage of acute stroke patients designated centers. Cincinnati prehospital scale (CPSS) is a commonly used screening tool and has been validated identify large vessel occlusion (LVO). This study addresses the impact county-based CPSS implementation suspected LVO comprehensive center (CSC).Dekalb County in Atlanta, Georgia, implemented CPSS-based protocol with score 3 last seen normal time < 24 h mandating transfer nearest CSC if added...
Background: Carotid free-floating-thrombus(CFT)is a rare cause of stroke describing an intraluminal thrombus that is loosely associated with the arterial wall and manifesting as filling defect fully surrounded by contrast. Unfortunately, there no clear consensus among experts on ideal treatment for CFT. Methods: Retrospective analysis acute ischemic stroke(AIS)patients diagnosed internal carotid CFT CTA between January2015-March2023.We aimed to compare two regimens: antiplatelet(APT)...
: Evaluating patients with ascending sensorimotor deficits has a broad differential diagnosis at initial presentation which can be further narrowed upon neurologic examination but may represent diagnostic and therapeutic dilemma in light of findings raising suspicion for multiple possible etiologies.
To present a case of contrast-induced encephalopathy (CIE) after IV thrombolysis (IVT) for acute ischemic stroke (AIS).
Vascular diseases are among the most common disorders that neurologists treat on a daily basis. Ischemic stroke is generally what comes to mind mention of vascular disorders. However, term inclusive multiple other pathologies. This chapter allows readers appreciate breadth this field by exploring various types lesions. In addition ischemic strokes, we will discuss cases hemorrhagic malformations, and uncommon entities such as dynamic occlusions rare genetic
Introduction PFO‐associated stroke is more common in young patients (<60 years) with less vascular risk factors, and an infarct pattern consistent embolic phenomena. These features are included the Risk of Paradoxical Embolization (RoPE) score which a high (≥ 7) indicates likelihood symptomatic PFO. However, carotid artery webs (CaW) have been reported same profile PFO might be detected. In this study, we calculated RoPE for CaW related strokes to identify how many these would potentially...
<h3>Objective:</h3> NA <h3>Background:</h3> Longitudinally extensive transverse myelitis (LETM) is caused by a myriad of etiologies. We present case Neuromyelitis Optica Spectrum Disorder (NMOSD)-related myelitis, initially seronegative, masquerading as VZV-related myelitis. <h3>Design/Methods:</h3> A report. <h3>Results:</h3> woman in her sixties reported one-month history bilateral lower extremity paresthesias and weakness. Days prior, she felt tingling on back with eruption painful rash,...
Introduction Loss of autoregulation after endovascular therapy (EVT) for large‐artery acute ischemic stroke (AIS) is well documented. [1] This might result in worse outcomes, despite successful recanalization, from hyper‐ or hypoperfusion with a risk hemorrhagic conversion larger volume, respectively. Transcranial doppler (TCD) was previously used to document this phenomenon using spontaneous fluctuations reactivity. Herein, we present patient suspected obstructive sleep apnea (OSA)...
Introduction: Carotid Web (CaW) is an underrecognized etiology for ischemic stroke. This entity has been shown to be amenable endovascular stenting, similar carotid atherosclerotic stenosis (CAS). We aimed assess procedural characteristics of stenting CaW as compared CAS. Methods: retrospectively analyzed a cohort patients at single comprehensive stroke center from October 2014 March 2021 who had undergone stent placement symptomatic CAS or CaW. Patients received other intervention (e.g....
Introduction: Patent foramen ovale (PFO) is present in a significant number of ESUS patients and paradoxical embolism from venous thromboembolism (VTE) often assumed to be the primary stroke mechanism. We hypothesized that not cause among with PFO based on markers coagulation hemostatic activation (MOCHA). Methods: presenting Emory Clinic January 1, 2017 December 31, 2020 were followed for median 13 months (IQR 8.1 - 21.7). MOCHA testing (d-dimer, prothrombin fragment 1.2,...
Introduction: The frequent presence of PFO in migraine patients with stroke has led to assumptions paradoxical embolism. Normal markers coagulation and hemostatic activation (MOCHA) effectively rule out active hypercoagulability venous thromboembolism. We hypothesized that ESUS have low frequency abnormal MOCHA. Methods: seen at the Emory Clinic from January 1, 2017 December 31, 2020 underwent MOCHA testing (d-dimer, prothrombin fragment 1.2, thrombin-antithrombin complex, fibrin monomer)...
arotid web (CaW) is a shelf-like fibrotic projection at the carotid bulb and constitutes an underrecognized cause of ischemic stroke.The histological natural history these lesions has not been investigated.Conversely, atherosclerotic have extensively documented to undergo dynamic processes cellular molecular levels, leading both positive negative remodeling. 1 Considering that 3-dimensional volumetric measurements on computed tomography angiography (CTA) for CaW size quantification...
A 28-year-old vegetarian woman with pernicious anemia developed progressive leg spasticity and psychosis leading to food paranoia severe malnutrition. She presented encephalopathy, anemia, hypoalbuminemia, deficiency of zinc vitamins B1, B6, B12. MRI revealed a lesion the splenium corpus callosum (figure 1) spinal cord changes 2). This case shows combination findings associated vitamin deficiencies: (B complex, Marchiafava-Bignami disease)1 (B12, subacute combined degeneration).2 Primary...
To report an unusual presentation of right-sided thalamic infarction causing mixed-aphasia.