- Acute Ischemic Stroke Management
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrhythmias and Treatments
- ECG Monitoring and Analysis
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
- Gastroesophageal reflux and treatments
- Heart Rate Variability and Autonomic Control
- Cardiac Structural Anomalies and Repair
- Cardiovascular Function and Risk Factors
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Imaging and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Non-Invasive Vital Sign Monitoring
Evangelisches Krankenhaus Bielefeld
2020-2025
University Hospital Leipzig
2023
Klinikum Bielefeld
2016
Sismanoglio General Hospital
2007-2008
Summary Recently, the clinical entity embolic stroke of undetermined source (ESUS) has been defined for patients with ischemic strokes, where neither a cardioembolic nor non-cardiac can be detected. These may suffer from asymptomatic atrial fibrillation (AF), terminating spontaneously and thus eluding detection. Implantable loop recorders (ILR) automatic AF detection algorithms detect short-lasting, subclinical AF. The aim this study was to prospectively assess predict in ESUS using ILR...
Undocumented atrial fibrillation (AF) is suspected as a main stroke cause in patients with embolic of undetermined source (ESUS), but its prevalence largely unknown. This prospective study therefore aimed at delineating the AF ESUS using continuous cardiac monitoring by implantable loop recorder (ILR) daily remote interrogation over period 3 years and clinical consequences, including recurrent stroke.In consecutive an diagnosis after complete work-up, ILR was implanted followed until...
Introduction: Atrial Fibrillation (AF) is detected in nearly 30% of patients undergoing cardiac monitoring after ischemic stroke. Studies investigating predictors AF showed mixed results. In this study, we aim to identify on insertable monitors (ICMs) and compare rates between cryptogenic stroke controls. Methods: The ANT icoagulation A nd St R oke Re C urrence T rial F I brillation Dete ted fter Stroke (ANTARCTICA) study an individual patient data meta-analysis prospective observational...
Atrial fibrillation (AF) is one of the most frequent causes stroke. Several randomized trials have shown that prolonged monitoring increases detection AF, but effect on reducing recurrent cardioembolism, ie, ischemic stroke and systemic embolism, remains unknown. We aim to evaluate whether a risk-adapted, intensified heart rhythm with consequent guideline conform treatment, which implies initiation oral anticoagulation (OAC), leads reduction cardioembolism.Find-AF 2 randomized, controlled,...
Abstract Endovascular thrombectomy (EVT) is the most effective treatment for acute ischemic stroke caused by large vessel occlusion (LVO). Yet, long-term outcome (LTO) and health-related quality of life (HRQoL) in these patients have rarely been addressed, as opposed to modified Rankin scale (mRS) recordings. We analysed demographic data, neuroimaging parameters 694 consecutive a maximum care hospital. In 138 with respect on receipt written informed consent, LTO HRQoL were collected over...
Approximately 20% of strokes are embolic undetermined source (ESUS). Undetected atrial fibrillation (AF) remains an important cause. Yet, oral anticoagulation in unselected ESUS patients failed secondary stroke prevention. Guidance on effective AF detection is lacking. Here, we introduce a novel, non-invasive risk assessment after ESUS.Catch-Up investigator-initiated, observational cohort study conducted between 2018 and 2019 at the Munich University Hospital. Besides clinical...
Abstract Background Evaluation of outcome after stroke is largely based on assessment gross function 3 months onset using scales such as mRS. Cognitive or social functions, level symptom burden emotional health are not usually assessed, nor data available long-term functional outcomes years stroke. Methods Analysis 1141 patients with AIS treated IVT from two major German university hospitals between 2017 and 2020. Patient characteristics short-term were analysed patient records. Long-term...
Detection of atrial fibrillation (AF) is one the primary diagnostic goals for patients on a stroke unit. Physician-based manual analysis continuous ECG monitoring regarded as gold standard AF detection but requires considerable resources. Recently, automated computer-based RR intervals was established to simplify detection. The present prospective study analyzes both methods head regarding specificity, sensitivity, and overall effectiveness.Consecutive without history or proof in admission...
Introduction: The embolic stroke of unknown source concept was introduced as a more rigid analysis patients with cryptogenic representing superselection cardioembolic stroke. These are particularly candidates for intermittent AF. As long AF has not been documented, current concepts do recommend oral anticoagulation.Implantable loop recorders (ILR) in ESUS may detect and establish the indication anticoagulation. aim this study to prospectively assess predict occurrence ILR after ESUS....