A5067624116- Transplantation: Methods and Outcomes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pulmonary Hypertension Research and Treatments
- Medical Imaging and Pathology Studies
- Cancer Immunotherapy and Biomarkers
- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Asthma and respiratory diseases
- Eosinophilic Esophagitis
- Lung Cancer Treatments and Mutations
- Cannabis and Cannabinoid Research
- Antifungal resistance and susceptibility
- Respiratory and Cough-Related Research
- Systemic Sclerosis and Related Diseases
- Inhalation and Respiratory Drug Delivery
- Mechanical Circulatory Support Devices
- Heavy metals in environment
- COVID-19 Clinical Research Studies
- Sarcoidosis and Beryllium Toxicity Research
- Melanoma and MAPK Pathways
- Advanced biosensing and bioanalysis techniques
- Medical and Biological Ozone Research
- Congenital Diaphragmatic Hernia Studies
Université Paris-Saclay
2018-2024
Newcastle University
2023-2024
Hôpital Marie Lannelongue
2017-2024
Université Paris-Sud
2018-2024
Inserm
2013-2024
Hôpital Paris Saint-Joseph
2020-2024
Centre Chirurgical Marie Lannelongue
2022-2023
Hypertension pulmonaire : physiopathologie et innovation thérapeutique
2022-2023
Hôpital Bichat-Claude-Bernard
2011-2022
Assistance Publique – Hôpitaux de Paris
2014-2021
Extracorporeal membrane oxygenation (ECMO) has become the standard of cardiopulmonary support during a sequential double lung transplant for pulmonary hypertension. Whether central or peripheral cannulation is best strategy these patients remains unknown. Our goal was to determine which by comparing 2 populations patients.We performed single-centre retrospective study based on an institutional prospective database.Between January 2011 and November 2016, 103 underwent We compared 54 who had...
Presence of anti-human leukocyte antigen donor-specific antibodies (DSAs) is associated with poor outcome after lung transplantation. Currently, DSAs are detected using the Luminex technique, which may be overly sensitive. The new C1q assay allows for exclusive detection complement (C1q)-binding antibodies, involved in antibody-mediated rejection. We investigated whether early complement-binding chronic allograft dysfunction (CLAD) and survival.From 2009 to 2012, transplant recipients from...
Aberrant expression of master phenotype regulators or alterations in their downstream pathways lung fibroblasts may play a central role idiopathic pulmonary fibrosis (IPF). Interrogating IPF fibroblast transcriptome datasets, we identified Forkhead Box F1 (FOXF1), DNA-binding protein required for development, as candidate actor IPF. Thus determined FOXF1 levels cultured from normal lungs vitro, and explored functions these cells using transient stable loss-of-function gain-of-function...
We aimed to review the clinical and biological presentation of granulomatosis associated with immune-checkpoint inhibitors (ICI) in patients melanoma explore its association classical sarcoidosis as well cancer response ICI. To this end, a retrospective study on 18 histologically proven ICI-induced over 12-year period single center, 67 similar cases reported literature, was conducted. Results indicate is an early side effect (median time onset: 2 months). Its presentation, predominant (90%)...
Background. We sought to determine whether invasive aspergillosis (IA) during the first year after lung transplantation increased risk of chronic allograft dysfunction (CLAD). Methods. retrospectively reviewed records 191 patients who underwent at our institution between January 2013 and December 2017. Screening for Aspergillus was with bronchial aspirates, bronchoalveolar lavage if indicated or surveillance bronchoscopy, radiography, computed tomography. used Fine Gray multivariable...
Background Lung or heart–lung transplantation (LT/HLT) for severe pulmonary hypertension (PH) as the primary disease indication carries a high risk of waiting list mortality and post-transplant complications. France UK both have coordinated PH patient services but with different referral pathways accessing LT services. Methods We conducted comparative analysis adult patients listed LT/HLT in France. Results included 211 (2006–2018) 170 (2010–2019). Cumulative incidence transplant, delisting...