A5089445654- Asthma and respiratory diseases
- Tracheal and airway disorders
- Allergic Rhinitis and Sensitization
- Respiratory and Cough-Related Research
- Neonatal Respiratory Health Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Dermatology and Skin Diseases
- Social Sciences and Policies
- Food Allergy and Anaphylaxis Research
- Religious and Theological Studies
- Respiratory viral infections research
- Cleft Lip and Palate Research
- Esophageal and GI Pathology
- Cystic Fibrosis Research Advances
- Coronary Interventions and Diagnostics
- Cardiovascular and Diving-Related Complications
- Pleural and Pulmonary Diseases
- Congenital Diaphragmatic Hernia Studies
- Cardiac Imaging and Diagnostics
- Craniofacial Disorders and Treatments
- Influenza Virus Research Studies
- Philosophy, Health, and Society
- Inhalation and Respiratory Drug Delivery
- Infant Health and Development
- Peripheral Neuropathies and Disorders
Complejo Hospitalario Universitario de Toledo
2017-2022
Hospital Virgen de la Salud
2013-2020
University of Castilla-La Mancha
2019
Santa Lucía University General Hospital
2012-2017
Instituto de Salud Carlos III
2001-2016
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2016
Universitat de Barcelona
2016
Government of Catalonia
2016
Complejo Hospitalario Universitario de Granada
2008-2015
Universidad de Murcia
2013
Iseganan, an antimicrobial peptide, is active against aerobic and anaerobic gram-positive gram-negative bacteria as well fungi yeasts. The drug has shown little resistance in vitro to be safe tolerated 800 patients with cancer treated for up 6 wk.To determine the efficacy of iseganan prevention ventilator-associated pneumonia (VAP).Mechanically ventilated United States Europe were randomized oral topical or placebo (1:1) six times per day while intubated 14 d. Patients eligible if within 24...
Questionnaires are widely used in epidemiological studies to measure eczema symptom prevalence, but there concerns regarding their accuracy if as a diagnostic tool.To compare the performance of validated questionnaire and standardized skin examination protocol employed second phase International Study Asthma Allergies Childhood (ISAAC).A total 30,358 schoolchildren aged 8-12 years from 18 countries were examined for flexural eczema. Parents also completed an questionnaire. We compared...
Since March 2020, the world is involved in COVID-19 pandemic, a disease caused by novel virus called SARS-CoV-2. Some authors have described ultrasonographic findings of pneumonia adults and children, but data on neonates are lacking. Our objective was to describe lung pattern newborns with SARS-CoV-2 infection during pandemic. Newborns who tested positive for PCR respiratory samples were evaluated point-of-care ultrasound (LU) from April 2020 included. LU performed bedside single...
Few epidemiological studies have compared the risk factors of asthma or wheezing between atopic and non‐atopic children. The objective this study was to determine if there are specific for current related status in schoolchildren. Schoolchildren 9–12 yr age from three Spanish cities (n = 2720) were subject a cross‐sectional (by questionnaire) atopy skin prick test) according ISAAC phase‐II protocol. Risk (in last 12 months) as reported by parents investigated among (positive test at least...
Abstract Hippocampal subfields differentially develop and age, they vary in vulnerability to neurodegenerative diseases. Innovation high-resolution imaging has accelerated clinical research on human hippocampal subfields, but substantial differences segmentation protocols impede comparisons of results across laboratories. The Subfields Group (HSG) is an international organization seeking address this issue by developing a histologically-valid, reliable, freely available protocol for T 2...
Abstract Aims: We assessed central-peripheral temperature gradient alteration for the diagnosis of late-onset neonatal sepsis and compared earliness detection this sign with altered blood cell count C-reactive protein. Method: Thirty-one preterm babies (<1500 g or <32 weeks) participated in an observational prospective study. Axillary (central) sole (peripheral) temperatures were continuously monitored a thermal probe (ThermoTracer; Dräger Medical AGF & Co. KgaA, Lübeck, Germany)...
HIV-2 is a neglected virus despite estimates of 1-2 million people being infected worldwide. The naturally resistant to some antiretrovirals used treat HIV-1 and therapeutic options are limited for patients with HIV-2.In this retrospective observational study, we analysed all HIV-2-infected individuals treated integrase strand transfer inhibitors (INSTIs) recorded in the Spanish cohort. Demographics, treatment modalities, laboratory values, quantitative RNA CD4 counts as well drug resistance...
The prognosis for late-onset sepsis depends largely on a timely diagnosis. We assess central-peripheral temperature difference monitoring as marker neonatal diagnosis.We performed prospective, observational study focusing cohort of 129 very low-birth-weight infants. Thermal gradient alteration was defined > 2°C maintained during 4 hours. then determined its association with the variable through logistic regression.We enrolled preterm babies in 52 months. alterations showed an adjusted odds...
The dismal outcome of pleuropericardial extramedullary multiple myeloma (EMM) reflects both the selection resistant disease and absence useful drugs. Carfilzomib dexamethasone should be explored in advanced EMM patients, even for bortezomib-resistant as may provide much longer overall survival than previously reported treatments.
Atopic dermatitis (AD) prevalence has considerably increased worldwide in recent years. Studying indoor environments is particularly relevant, especially industrialised countries where many people spend 80% of their time at home, children. This study aimed to identify the potential association between AD and energy source (biomass, gas electricity) used for cooking domestic heating a Spanish schoolchildren population. As part ISAAC (International Study Asthma Allergies Childhood) phase III...