A5026704331- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Vestibular and auditory disorders
- Sepsis Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Ophthalmology and Eye Disorders
- Stroke Rehabilitation and Recovery
- Glaucoma and retinal disorders
- Cardiac Arrest and Resuscitation
- Cardiovascular Syncope and Autonomic Disorders
- Bacterial Infections and Vaccines
- Cerebral Venous Sinus Thrombosis
- Intracerebral and Subarachnoid Hemorrhage Research
- Infectious Diseases and Tuberculosis
- Cardiac Structural Anomalies and Repair
- Infectious Encephalopathies and Encephalitis
- Homicide, Infanticide, and Child Abuse
- Muscle activation and electromyography studies
- Health Promotion and Cardiovascular Prevention
- Renal and related cancers
- Cancer, Lipids, and Metabolism
- Heart Rate Variability and Autonomic Control
- Neutropenia and Cancer Infections
Alfried Krupp Hospital
2020-2025
Population Health Research Institute
2024
Kyorin University
2024
McMaster University
2024
Western University of Health Sciences
2024
Johns Hopkins Medicine
2021-2023
Johns Hopkins University
2021-2023
American University of Beirut
2018-2021
University of Duisburg-Essen
2005-2021
University of Glasgow
2011-2021
Direct oral anticoagulants (DOACs) reduce the rate of thromboembolism in patients with atrial fibrillation but benefits and risks survivors intracerebral haemorrhage are uncertain. We aimed to determine whether DOACs risk ischaemic stroke without substantially increasing recurrent haemorrhage. PRESTIGE-AF is a multicentre, open-label, randomised, phase 3 trial conducted at 75 hospitals six European countries. Eligible were aged 18 years or older spontaneous haemorrhage, fibrillation, an...
Because robotic devices record the kinematics and kinetics of human movements with high resolution, we hypothesized that measures collected longitudinally in patients after stroke would bear a significant relationship to standard clinical outcome and, therefore, might provide superior biomarkers.In moderate-to-severe acute ischemic stroke, used scales measure arm movement 7, 14, 21, 30, 90 days event at 2 sites. The robots are interactive speed, position, force so calculated kinematic...
In the present study, timing of conditioned eyeblink responses (CRs) was investigated in cerebellar patients and age-matched controls using a standard delay paradigm. Findings were compared with previously published data CR incidences same patient population (Gerwig et al., 2003; Timmann 2005). Sixteen pure cortical degeneration (spinocerebellar ataxia type 6 idiopathic ataxia), 14 lesions within territory superior artery, 13 infarctions posterior inferior artery included. The affected...
This review explores ferroptosis, a form of regulated cell death reliant on iron-induced phospholipid peroxidation, in diverse physiological and pathological contexts, including neurodegenerative disorders, ischemia-reperfusion. In the realm cardiovascular diseases, it significantly contributes to cardiomyopathies, dilated cardiomyopathy, hypertrophic restrictive cardiomyopathy. Ferroptosis involves intricate interactions within cellular iron metabolism, lipid balance between polyunsaturated...
Emergency Department (ED) visits for suicide attempts have been described worldwide; however, the populations studied were predominantly Western European, North American, or East Asian. This study aims to describe epidemiology of ED patients presenting post-suicide attempt an academic medical center in Lebanon and report on factors that affect disposition.A retrospective cohort was conducted between 2009 2015. Patients any age group included if they had presented after a attempt. with...
Objectives Patients with congestive heart failure (CHF) may be at a higher risk of mortality from sepsis than patients without CHF due to insufficient cardiovascular reserves during systemic infections. The aim this study is compare sepsis-related between and no in presenting tertiary medical centre. Design A single-centre, retrospective, cohort study. Setting Conducted an academic emergency department (ED) January 2010 2015. Patients’ charts were queried via the hospital’s electronic...
Objective One of the greatest challenges in clinical trial design is dealing with subjectivity and variability introduced by human raters when measuring end-points. We hypothesized that robotic measures capture kinematics movements collected longitudinally patients after stroke would bear a significant relationship to ordinal scales potentially lead development more sensitive motor biomarkers could improve efficiency cost trials. Materials methods used assay measure arm movement 208 7, 14,...
Abstract Background This study examines the relationship between universal health coverage (UHC) and burden of emergency diseases at a global level. Methods Data on Disability-Adjusted Life Years (DALYs) from conditions were extracted Institute for Health Metrics Evaluation (IHME) database years 2015 2019. UHC, measured using two variables 1) essential services 2) proportion population spending more than 10% household income out-of-pocket care expenditure, World Bank Database preceding our...
This case report describes a young woman who presented with slowly progressing weakness of the proximal limb muscles and slight decrease muscle tone but otherwise unremarkable neurological history. Diagnostic workup revealed fatty degeneration girdle an excessive increase parathyroid hormone as result severe vitamin D deficiency. Secondary hyperparathyroidism was diagnosed, deficits resolved after treatment underlying endocrinopathy.
Background Although the established measure of disability post stroke, modified Rankin Scale emphasizes motor function and may underestimate importance cognitive impairment in more disabled patients. A subset four items from National Institutes Health Stroke has been proposed to assess after stroke (Cog-4), correlate with Scale. Items correspond orientation, executive function, language, inattention. We investigated responsiveness Cog-4 treatment thrombolysis whether it offers information...
Blunt abdominal trauma in the setting of polycystic kidney disease is still scantly described literature and management guidelines such patients are not well-established. The authors herein present a case hypovolemic shock secondary to segmental renal artery bleed 75-year-old man with after minimal blunt trauma, who underwent successful selective arterial embolization, provide thorough review similar cases literature, while shedding light on important considerations when dealing patients. It...
Out-of-hospital cardiac arrest (OHCA) remains one of the most common causes death. There is a scarcity evidence concerning prevalence bacteraemia in patients presenting to Emergency Department (ED). We aimed determine OHCA ED, as well study association between and in-hospital mortality patients. In addition, antibiotic use during resuscitation was examined.This 200 adult who presented ED 2015 2019. Bacteraemia confirmed if at least blood culture bottles grew non-skin flora pathogen or two...
Meningitis is an inflammatory condition affecting the meninges surrounding brain and spinal cord. can be triggered by various factors, including infectious agents like viruses bacteria non-infectious contributors such as cancer or head injuries. The impact of meningitis on central nervous system involves disruptions in blood–brain barrier, cellular infiltrations, structural alterations. clinical features that differentiate between tuberculous (TBM) non-tuberculous (NTM) are discussed this...
Ein kryptogener ischämischer Schlaganfall wird nach den TOAST-Kriterien angenommen wenn andere Ursachen wie eine kardiale Emboliequelle, Makroangiopathie, ein lakunärer Infarkt oder Schlaganfallätiologie nicht nachgewiesen werden konnten. Während für die meisten definierten Schlaganfallätiologien mittlerweile gezielt Sekundärpräventionsstudien durchgeführt wurden, bestand bisher bei Patienten mit kryptogenem das Problem, dass diese Ätiologie ausreichend operational definiert ist. Das neue...
Although there are well known sex differences in older patients with ischemic stroke receiving acute reperfusion treatments, is paucity of data younger patients.We investigated sex-related clinical presentation, etiology and short-term outcomes consecutive young (AIS) below the age 50 years mechanical thrombectomy (MT) between January 2011 May 2021 a tertiary center.We identified total 202 MT, 51% being female. Young female AIS were significantly (39 ± 8 vs. 43 7 years, p < 0.001), presented...