Omid Halse
A5033989070- Acute Ischemic Stroke Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Innovations in Medical Education
- Venous Thromboembolism Diagnosis and Management
- Stroke Rehabilitation and Recovery
- Cerebrovascular and Carotid Artery Diseases
- Atrial Fibrillation Management and Outcomes
- COVID-19 and healthcare impacts
- Clinical Reasoning and Diagnostic Skills
- Traumatic Brain Injury and Neurovascular Disturbances
- Empathy and Medical Education
- Pharmaceutical Practices and Patient Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Reflective Practices in Education
- Long-Term Effects of COVID-19
- Health Sciences Research and Education
- S100 Proteins and Annexins
- Intracranial Aneurysms: Treatment and Complications
- Medical Education and Admissions
- Retinal and Optic Conditions
- Hospital Admissions and Outcomes
- Cerebrovascular and genetic disorders
- COVID-19 Clinical Research Studies
- Simulation-Based Education in Healthcare
- Genetic Syndromes and Imprinting
Imperial College Healthcare NHS Trust
2012-2025
Imperial College London
2014-2025
Charing Cross Hospital
2014-2025
Bangkok University
2023
Campbell Collaboration
2021
The University of Sydney
2015-2017
Royal Prince Alfred Hospital
2017
University of Chile
2017
NIHR Leicester Cardiovascular Biomedical Research Unit
2017
University of Leicester
2017
Anticipating the burden of intracerebral haemorrhage is crucial for proactive management and building resilience against future health challenges. Prior forecasts are based on population demography to a lesser extent epidemiological trends. This study aims utilise selected modifiable risk factors socio-demographic indicators forecast incidence mortality in Europe between 2019 2050.
Direct oral anticoagulants (DOACs) reduce the rate of thromboembolism in patients with atrial fibrillation but benefits and risks survivors intracerebral haemorrhage are uncertain. We aimed to determine whether DOACs risk ischaemic stroke without substantially increasing recurrent haemorrhage. PRESTIGE-AF is a multicentre, open-label, randomised, phase 3 trial conducted at 75 hospitals six European countries. Eligible were aged 18 years or older spontaneous haemorrhage, fibrillation, an...
A critical decision-step in the emergency treatment of ischemic stroke is whether or not to administer thrombolysis — a that can result good recovery, deterioration due symptomatic intracranial haemorrhage (SICH). Certain imaging features based upon early computerized tomography (CT), combination with clinical variables, have been found predict SICH, albeit modest accuracy. In this proof-of-concept study, we determine machine learning CT images which patients receiving tPA will develop SICH...
<h3>Importance</h3> Cryptogenic strokes constitute approximately 40% of ischemic in young adults, and most meet criteria for the embolic stroke undetermined source (ESUS). Two randomized clinical trials, NAVIGATE ESUS RESPECT ESUS, showed a high rate recurrence older adults with but prognosis prognostic factors among younger individuals is uncertain. <h3>Objective</h3> To determine rates associated recurrent death new-onset atrial fibrillation (AF) adults. <h3>Design, Setting,...
Background: The COVID-19 pandemic is having major implications for stroke services worldwide. We aimed to study the impact of national lockdown period during outbreak on and transient ischemic attack (TIA) care in London, UK. Methods: retrospectively analyzed data from a quality improvement registry consecutive patients presenting with acute TIA Stroke Department, Imperial College Health Care Trust London (between March 23rd 30th June 2020). As controls, we evaluated clinical reports metrics...
Background and purpose. Mechanical thrombectomy (MT) is the standard of care for eligible patients with a large vessel occlusion (LVO) acute ischemic stroke. Among undergoing MT there has been uncertainty regarding role intravenous thrombolysis (IVT) previous trials have yielded conflicting results clinical outcomes. We aim to investigate clinical, reperfusion outcomes safety or without IVT stroke due anterior circulation LVO. Materials Methods. This observational, prospective, single-centre...
<b><i>Introduction:</i></b> We examined the impact of coronavirus disease 2019 (COVID-19) pandemic on our regional stroke thrombectomy service in UK. <b><i>Methods:</i></b> This was a single-center health evaluation. began testing for COVID-19 3 March and introduced modified “COVID Stroke Thrombectomy Pathway” 18 March. analyzed clinical, procedural outcome data 61 consecutive patients between 1 January 30 April. compared February (“pre-COVID,”...
Uncertainty is a common and increasingly acknowledged problem in clinical practice. Current single best answer (SBA) style assessments test areas where there one correct answer, as the approach to assessment impacts on learning, these exams may poorly prepare our future doctors handle uncertainty. We therefore, need modify emphasize reasoning introduce possibility of more than 'correct' answer. have developed prioritization questions (CPQs), novel formative tool which students prioritize...
Reflection is a core component of good medical practice and growing importance given increasing rates burnout in the field medicine. Schwartz Rounds (SRs) are group-based model reflective practice. This study explored utility student-specific as medium for amongst students entering their first year clinical attachments, how effective these compared to standard organisation-wide Rounds.Three Medical Student (MSSRs) were piloted over course at major teaching hospital, focussed on theme: "Is...
Background It remains uncertain whether the drip‐and‐ship (DS) strategy (transport to nearest primary stroke centers) or mothership (MS) model (direct transportation comprehensive center) is organizational associated with best functional outcome in acute patients large vessel occlusion. In this study, we compared periprocedural complications and outcomes at 90 days of occlusion anterior circulation directly admitted our center those referred from centers treated mechanical thrombectomy....
Open-book examinations (OBEs) will likely become increasingly important assessment tools. We investigated how access to open-book resources affected questions testing factual recall, which might be easy look-up, versus higher-order cognitive domains. Few studies have OBEs using modern Internet or as summative assessments. compared performance on an examination conducted a traditional closed-book exam (CBE) in 2019 (N = 320) and remote OBE with free 2020 337) due COVID-19. This summative,...
This study compared knowledge attainment and student enjoyment engagement between clinical case vignette, patient-testimony videos mixed reality (MR) teaching via the Microsoft HoloLens 2, all delivered remotely to third year medical students. The feasibility of conducting MR on a large scale was also assessed.Medical students in Year 3 at Imperial College London participated three online sessions, one each format. All were expected attend these scheduled sessions complete formative...
Estimating patient weight forms an important part of emergency ischemic stroke management guiding the dose alteplase (tissue-type plasminogen activator). Weighing patients with can be logistically challenging and time consuming, potentially delaying treatment times. We aimed to assess reliability approximating determine recombinant tissue-type activator whether potential inaccurate dosing affected outcomes.Two hundred forty-two consecutive were studied at a large tertiary center. Estimated...
The global COVID-19 pandemic led many stroke centres worldwide to shift from in-person telemedicine consultations assess patients with transient ischaemic attacks (TIAs). We aimed investigate the impact of during on management and outcome TIA.We retrospectively analysed data a registry consecutive TIA assessed at Stroke Department, Imperial College Health Care Trust, London, national lockdown period (between March 23 2020 30 June 2020). As controls, we evaluated clinical reports quality...
Although previous studies investigated the main predictors of outcomes after endovascular thrombectomy (EVT) in patients aged 80 years and older, less is known about impact procedural features on elderly patients. The aim this study was to investigate influence EVT technical procedures 3-month a population older.
Infections and fever after stroke are associated with poor functional outcome or death. We assessed whether prophylactic treatment anti-emetic, antibiotic, antipyretic medication would improve in older patients acute stroke.We conducted an international, 2∗2∗2-factorial, randomised, controlled, open-label trial blinded assessment aged 66 years ischaemic intracerebral haemorrhage a score on the National Institutes of Health Stroke Scale ≥ 6. Patients were randomly allocated (1:1) to...
Abstract Adequate secondary prevention in survivors of intracerebral hemorrhage (ICH) who also have atrial fibrillation (AF) is a long-standing clinical dilemma because these patients are at increased risk recurrent ICH as well ischemic stroke. The efficacy and safety oral anticoagulation, the standard preventive medication for stroke with AF, AF uncertain. PRESTIGE-AF an international, phase 3b, multi-center, randomized, open, blinded end-point assessment (PROBE) trial that compared direct...
Abstract Background Mechanical thrombectomy (MT) remains an effective treatment for patients with acute ischemic stroke receiving oral anticoagulation (OAC) and large vessel occlusion (LVO). However, to date, it unclear whether MT is safe in on OAC. Aims In our study, we performed a propensity-matched analysis investigate the safety efficacy of anticoagulants. A propensity score method was used target causal inference observational study design. Methods This observational, prospective,...
Abstract Background Team‐based learning (TBL) currently relies on single best answer questions (SBAQs) to provide immediate feedback. Very short (VSAQs) are a reliable and discriminatory alternative that encourage learners use more authentic clinical reasoning strategies compared SBAQs. However, the challenge of marking VSAQs has limited their integration into TBL; we therefore explored feasibility within TBL session. Methods An online platform was developed allow during sessions. As part...