- Gut microbiota and health
- Gastroesophageal reflux and treatments
- Reproductive tract infections research
- Helicobacter pylori-related gastroenterology studies
- HIV Research and Treatment
- Diet and metabolism studies
- Meat and Animal Product Quality
- Clostridium difficile and Clostridium perfringens research
- Nutritional Studies and Diet
- Psoriasis: Treatment and Pathogenesis
- Phytochemicals and Antioxidant Activities
- Agriculture Sustainability and Environmental Impact
- Herpesvirus Infections and Treatments
- Eosinophilic Esophagitis
- Infant Nutrition and Health
- Pharmaceutical and Antibiotic Environmental Impacts
- Infant Health and Development
- Cervical Cancer and HPV Research
- Cassava research and cyanide
- Edible Oils Quality and Analysis
- Gastrointestinal motility and disorders
- Pelvic floor disorders treatments
- Geochemistry and Elemental Analysis
- Epigenetics and DNA Methylation
- Oral microbiology and periodontitis research
University of California, Davis
2018-2024
University of California Davis Medical Center
2021
Scripps Research Institute
2004
In spite of controversy, recent studies present evidence that a microbiome is in the human placenta. However, there limited information about potential equine placental microbiome. study, we characterized microbial population placenta (chorioallantois) healthy prepartum (280 days gestation, n = 6) and postpartum (immediately after foaling, 351 11) mares, using 16S rDNA sequencing (rDNA-seq). both groups, majority bacteria belonged to phyla Proteobacteria, Firmicutes, Actinobacteria,...
ABSTRACT We have derived and characterized a highly pathogenic molecular isolate of feline immunodeficiency virus subtype C (FIV-C) CABCpady00C. Clone FIV-C36 was obtained by lambda cloning from cats that developed severe disease when infected with CABCpady00C (Abbotsford, British Columbia, Canada). Env is 96% identical to the noninfectious FIV-C sequence deposited in GenBank (FIV-Cgb; accession number AF474246 ) (A. Harmache et al.) but much more divergent compared subgroup A clones...
The microbiome is an integral and dynamic component of the host emerging as a critical determinant immune responses; however, its influence on vaccine immunogenicity largely not well understood. Here, we examined pivotal relationship between mucosal vaccine-induced responses by assessing longitudinal changes in vaginal rectal profiles after intradermal immunization with human immunodeficiency virus type 1 (HIV-1) DNA adult rhesus macaques that received two prior primes. We report both...
Brewer's spent grain (BSG) was dried via infra-red drying (IRD) or hot-air (HAD) and milled into fine powders. Proximate analysis (moisture, protein, fat, ash, carbohydrates by difference), water activity, dietary fiber, total soluble phenolics, antioxidant capacity analyses were performed to characterize compare both types of BSG Mice feeding the two BSG, each at three different concentrations, conducted effects on health indicators determine evidence dose response. Weights body, feed...
Abstract Olive pomace (OP) is the main by‐product of olive oil extraction. After pit and skin removal, OP pulp has high concentrations dietary fiber phenolics with antioxidant capacity. This study evaluated mice health benefits drum‐dried pitted obtained after first second Fresh was steam blanched, then pits skins separated in a pulper/finisher, milled. characterized by proximate analysis, total soluble (TSP), individual phenolics, fiber. Drum‐dried from extraction formulated at 10% 20% fat...
It is estimated that more than half of the world population has been infected with Helicobacter pylori. Most newly acquired H. pylori infections occur in children before 10 years age. We hypothesized early life infection could influence composition microbiome at mucosal sites distant to stomach. To test this hypothesis, we utilized infant rhesus macaque monkey as an animal model natural colonization determine impact on lung and oral during a window postnatal development. From cohort 4-7...
The use of organic byproducts, such as brewery spent grain (BSG), a major byproduct the beer-brewing industry, has increased in recent years. BSG is rich fiber, proteins, polyphenols, vitamins, and minerals, all these compounds remain untapped during brewing process considered potential source bioactive molecules with health benefits. In this study, two types, regular fines fraction, were evaluated. Proximate, amino acid, dietary fiber analyses performed to compare characteristics both...
Abstract Cervicovaginal bacteria cause inflammation which in turn increases HIV risk. Profiling the cervicovaginal microbiome, therefore, is instrumental for vaccine development. We show that microbiome profile captured by lavage comparable to samples obtained vaginal swabs. Thus, may serve as a sampling strategy NHP studies.
In this study, we examined the total bacterial community associated with ureolytic biomineralization from urine drainage systems. Biomineral samples were obtained 11 California Department of Transportation public restrooms fitted waterless, low-flow, or conventional urinals in 2019. Following high throughput 16S rRNA Illumina sequences processed using DADA2 pipeline, microbial diversity assessment 169 biomineral and resulted 3,869 reference aggregated as 598 operational taxonomic units...
It is estimated that more than half of the world population has been infected with