A5062320911- Cardiac Valve Diseases and Treatments
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Congenital Heart Disease Studies
- Aortic Disease and Treatment Approaches
- Cardiac tumors and thrombi
- Neuroendocrine Tumor Research Advances
- Galectins and Cancer Biology
- Vascular Anomalies and Treatments
- Sarcoma Diagnosis and Treatment
- Peptidase Inhibition and Analysis
- Tracheal and airway disorders
- Lysosomal Storage Disorders Research
- Vascular Tumors and Angiosarcomas
- Renal Diseases and Glomerulopathies
- Chronic Kidney Disease and Diabetes
- Shoulder Injury and Treatment
- Coronary Interventions and Diagnostics
- Cardiac Arrest and Resuscitation
- Dialysis and Renal Disease Management
- Cardiac and Coronary Surgery Techniques
- Shoulder and Clavicle Injuries
- Transplantation: Methods and Outcomes
- Streptococcal Infections and Treatments
Hôpital Européen Georges-Pompidou
2017-2025
Centre Pompidou
2024
Assistance Publique – Hôpitaux de Paris
2017-2023
Université Paris Cité
2017-2023
Inserm
2022-2023
Hôpital Bichat-Claude-Bernard
2018-2021
Université Claude Bernard Lyon 1
2021
Post myocardial infarction ventricular septal defect (PMI-VSD) complicated by refractory cardiogenic shock is associated with an extremely high mortality rate. We sought to evaluate the factors in-ICU in patients PMI-VSD-related shock. Patients PMI-VSD shock, admitted 10 French tertiary centers between 2008 and 2022, were retrospectively included. The primary outcome was mortality. timing of surgery classified as early (≤ 7 days) or late (> days). Multivariable analysis performed identify...
ABSTRACT Valve interstitial cells (VICs) play a critical role in aortic valve calcification and angiogenic processes associated with calcific stenosis (CAVS). Within the same valve, VICs from differently calcified regions can exhibit diverse phenotypic functional properties. We hypothesised that isolated noncalcified (NC‐VICs) (C‐VICs) areas of human valves possess distinct characteristics. In this study, we C‐VICs NC‐VICs 23 obtained after replacement due to CAVS. Both VIC types exhibited...
Carmat bioprosthetic total artificial heart (Aeson; A-TAH) is a pulsatile and autoregulated device. The aim of this study to evaluate level hemolysis potential acquired von Willebrand syndrome after A-TAH implantation.We examined the presence in adult patients receiving support (n=10) during their whole clinical follow-up comparison with control subjects Heartmate II or III support. We also performed fluid structure interaction model coupled computational dynamics simulation resulting shear...
The CARMAT-Total Artificial Heart (C-TAH) is designed to provide heart replacement therapy for patients with end-stage biventricular failure. This report details the reliability and efficacy of autoregulation device control mechanism (auto-mode), mimic normal physiologic responses changing patient needs. Hemodynamic data from a continuous cohort 10 implanted device, recorded over 1,842 support days in auto-mode, were analyzed respect daily C-TAH uses embedded pressure sensors regulate pump...
Abstract Pulsatile Carmat bioprosthetic total artificial heart (C-TAH) is designed to be implanted in patients with biventricular end-stage failure. Since flow variation might contribute endothelial dysfunction, we explored circulating biomarkers after C-TAH implantation seven and compared the manual autoregulated mode. Markers of dysfunction regeneration were before during a 6- 9-month follow-up implantation. The was divided into three periods (< 3, 3–6, > 6 months) used estimate...
Background Bioprosthetic heart valves (BHVs) are less thrombogenic than mechanical prostheses; however, BHV thrombosis has been proposed as a risk factor for premature degeneration. Objectives We aimed to explore whether fibrin deposition on bovine pericardium tissue could lead calcification. Method Fibrin clot was obtained by blending three reagents, namely, CRYOcheck™ Pooled Normal Plasma (4/6), + phospholipids (Thrombinoscope BV), and 100 mM calcium (1/6), deposited discs. Non-treated...
Central picture legendHALT visualized through CT-scan imaging on an INSPIRIS bioprosthesis at the 3-month mark. messageThe rare HALT RESILIA tissue occurred exclusively in patients under antiplatelet therapy.Post operative anticoagulant strategies could be preferred to enhance valve durability.
Background: The modified Bentall procedure is a standard surgical approach for aortic root pathologies, including aneurysms, endocarditis with abscess, and dissections. Despite requiring valve replacement, this yields excellent results. Prosthesis selection should be individualized based on patient characteristics, contraindications to anticoagulation, preference. This study aims assess early mid-term outcomes of the using 4th generation pericardial valve. Methods: multicentric observational...
Primary cardiac synovial sarcoma is an extremely rare disease. Its prognosis poor with a median survival time of 24 months, even when adequate and timely treatment given. This case reports 61-year-old woman presenting primary 8-year following surgical adjuvant chemotherapy.
Hunter syndrome is a rare disease leading to glycosaminoglycan accumulation in tissues. Multiple organs are involved, but prognosis mainly conditioned by cardiac and respiratory failures. Cardiac valvular impairment quite common aortic root dilatation rarely described. This article covers case of surgical replacement due valve insufficiency documented with magnetic resonance computed tomography angiographies. Anatomic pathology reported both aorta mucoid overload elastic fibre depletion....
ObjectivesEnd-stage kidney diseases (ESKD) is considered a public health problem in both developed and emerging countries. This study aimed to assess the epidemiological profile of ESKD patients undergoing hemodialysis (HD) Sidi Bel Abbes city.MethodsThis retrospective, observational descriptive was conducted from January 2015 December 2018 involving 698 Renal replacement therapy, including 673 HD.ResultsThe prevalence 805.57 pmp. Regarding HD patients, there slight predominance males:...