Objectives: To investigate the correlation between iron deposition changes in lesioned thalamic nuclei and presence severity of central post-stroke pain (CPSP) after infarction using quantitative susceptibility mapping (QSM) technique. Methods: We consecutively enrolled patients with unilateral chronic radiological examination conformed . Detailed multidimensional characteristics measured as follows: Douleur Neuropathique 4 (DN4) questionnaire for validation neuropathic diagnosis, Short-Form...

Propionate, 3-hydroxypropionate (3HP), methylcitrate, related compounds, and ammonium accumulate in body fluids of patients with disorders propionyl-CoA metabolism, such as propionic acidemia. Although liver transplantation alleviates hyperammonemia, high concentrations propionate, 3HP, methylcitrate persist fluids. We hypothesized that conserved metabolic perturbations occurring transplanted result from the simultaneous presence propionate 3HP investigated inter-relations metabolism...

Background and purpose Previous studies have reported about inflammation processes (IPs) that play important roles in aneurysm formation rupture, which could be driven by blood flow. IPs can identified using aneurysmal wall enhancement (AWE) on high-resolution black-blood MRI (BB-MRI) flow haemodynamics demonstrated four-dimensional-flow (4D-flow MRI). Thus, this study investigated the associations between AWE unruptured intracranial aneurysms (IA) combining 4D-flow BB-MRI. Materials methods...

Purpose To compare the ability of diffusion parameters obtained by stretched-exponential and kurtosis models diffusion-weighted imaging (DWI) to distinguish between patients with primary aldosteronism (PA) healthy controls (HCs) in renal assessment. Materials methods A total 44 participants (22 22 HCs) underwent MRI an 11 b-value DWI sequence a 3 (DKI) from June 2021 April 2022. Binary logistic regression was used construct combining different parameters. Receiver-operating characteristic...

Previous studies have hypothesized that intracranial aneurysm (IA) morphology interacts with hemodynamic conditions. Magnetic resonance imaging (MRI) provides a single image modality solution for both morphological and measurements IA. This study aimed to explore the interaction between hemodynamics of IA using black-blood MRI (BB-MRI) 4D flow MRI.A total 97 patients unruptured were recruited this study. The size, size ratio (SR), minimum wall thickness (mWT) measured BB-MRI. Velocity, blood...

Repetitive transcranial magnetic stimulation (rTMS) is increasingly used to treat neuropsychiatric disorders. Inhibitory and excitatory regimens have been both adopted but the exact mechanism of action remains unclear, investigating their differential effects on laminar diffusion profiles neocortex may add important evidence. Twenty healthy participants were randomly assigned receive a low-frequency/inhibitory or high-frequency/excitatory rTMS targeting left dorsolateral prefrontal cortex...

Inflammation and hemodynamics are interrelated risk factors for intracranial aneurysm rupture. This study aimed to identify the relationship between these from an individual-patient perspective using biomarkers of wall enhancement (AWE) derived high-resolution magnetic resonance imaging (HR-MRI) hemodynamic parameters by four-dimensional flow MRI (4D-flow MRI).A total 29 patients with unruptured aneurysms larger than 4 mm were included in this prospective cross-sectional study. A 24 had AWE...

Controlling the spontaneous directional transport of droplets plays an important role in application microchemical reactions and microdroplet detection. Although relevant technologies have been widely studied, existing droplet strategies still face problems complex structure, single function, poor flexibility. Inspired by strategy nature, asymmetric wettability surface with microcone channels (AWS-MC) is prepared on a flexible fabric combining modification femtosecond laser manufacturing...

Abstract Background Differentiation of glioma and solitary brain metastasis (SBM), which requires biopsy or multi-disciplinary diagnosis, remains sophisticated clinically. Histogram analysis MR diffusion molecular imaging hasn’t been fully investigated for the differentiation may have potential to improve it. Methods A total 65 patients with newly diagnosed metastases were enrolled. All underwent DWI, IVIM, APTW, as well T1W, T2W, T2FLAIR, contrast-enhanced T1W imaging. The histogram...

Conventional spinal magnetic resonance imaging (MRI) cannot provide accurate diagnosis and surgical planning; thin-layer scanning can enhance the diagnostic efficacy. This study aimed to investigate value of 3-dimensional (3D) (MR) in preoperative evaluation lumbar disc herniation, with a focus on application Multi-Echo iN Steady-state Acquisition (MENSA) sequence.

Background: Conventional reference multi-contrast black-blood (BB) MRI can be used for measuring luminal stenosis severity and plaque components, its performance has been validated by intra- inter-reader reproducibility test histology. Recently, a set of 3D BB sequences have developed, but accuracy reliability not well investigated. In this study, we evaluated the (3D-MERGE, T2-VISTA, SNAP) comparing it with vessel wall assessing reproducibility. Methods: total, 27 patients were recruited in...

Background Aneurysm inflow angle has been shown to be associated with hemodynamic changes by computational fluid dynamics. However, these studies were based on single aneurysm model and limited side‐wall aneurysms. Purpose To investigate the association between morphology, hemodynamic, inflammation of intracranial bifurcation Study type Prospective. Population A total 62 patients (aged 58.34 ± 12.39, 44 female) 59 unruptured aneurysms 17 included. Field strength/sequence 3.0 T; 3D fast field...

In this work, we propose a preoperative magnetic resonance examination of patients with lumbar disc herniation using the 3D MENSA sequence. This sequence was superior to cube, cube stir in subjective and objective evaluation. The MRI is able clearly depict nerve roots offer desirable contrast between roots, ligamentum flavum, bone, intervertebral discs. Patients degeneration can effectively benefit from since it provides informative imaging information help understand compression adjacent...

Accurate preoperative risk stratification is of critical importance for determine patients who will benefit from liver resection. Our study developed three subgroups with HCC associated different prognosis (RFS and OS) after resection based on MR imaging features using the Survival Classification Regression Tree (CART) method. The generated CART method demonstrated good discriminatory preoperatively prognosis. Therefore, model this present may help clinicians to consider non-surgical...

Improving image resolution by denoising is an important research goal in MRI reconstruction. An emerging technique, deep learning reconstruction (DLR), has shown great potential denoising. In this study, we included 37 patients with pathologically diagnosed hepatic malignancy, and compared the quality of DLR original regarding dual echo T1 weighted sequence, diffusion imaging (DWI) fat-suppressed gadolinium-enhancement. It was that significantly improved reducing background noise, thus...

At present, the resolution of magnetic resonance image is still limited to detection pancreatic space occupying lesions. In this work, quantitative and qualitative analysis images T1WI DWI with built-in DL Recon was carried out. The results showed that obtained by sequence were better than original in terms SNR, CNR subjective scores. It confirmed deep learning reconstruction can improve has potential lesions pancreas.

Sentinel lymph nodes(SLN) status is one of the most important indicators affecting breast cancer patient treatment and prognostic. Thus, a non-invasive diagnostic method capable accurately predicting SLN great value in selecting patients who would benefit from therapy. In this study, we investigate performance different [pN0, pN0 (i+), pN1mi, pN1] using dynamic contrast-enhanced (DCE) MRI. We found that (1) Krans, Kep, Ve are significantly status, (2) Ktrans best single parameter for...

Magnetic resonance imaging (MRI) is a useful tool to diagnose lumbar endplate inflammation. It thus important improve diagnostic accuracy by improving image quality. In this study, we compared signal-to-noise ratio (SNR), contrast noise (CNR) and subjective scores between original images deep learning reconstruction (DL Recon) in 31 patients diagnosed with was observed that the reconstructed outperformed conventional terms of both objective values.

In this study, we aim to investigate the performance of quantitative measurements from synthetic MRI in predicting disease activity Graves’ ophthalmopathy (GO).40 patients with different Clinical Activity Scores are investigated. We found a trend that muscles’ T1, T2 and PD values increased increasing CAS level, spatially for values. Furthermore, fact escalation ‘inactive’ groups compared healthy controls, indicate staging may underestimate activity. conclude have potential predict clinical...

Motivation: The potential of DLR to improve the quality liver acquisition with volume acceleration (LAVA) sequence images and its impact on lesion diagnosis has not been extensively reported. Goal(s): This study aims investigate utility in MR by comparing image diagnostic efficacy original LAVA venous phase DL-LAVA sequence. Approach: performance were compared Results: results revealed that significantly improved sequence, was superior. Impact: show can which may detection liver-related...

Motivation: Triple-negative breast cancer (TNBC) is a highly malignant and prognostically challenging subtype of often elusive in conventional MRI scans [1.4.5]. Three-Dimensional Amide Proton Transfer Imaging (3D-APT), non-invasive molecular imaging technique, shows promise improving TNBC diagnosis. Goal(s): This study aimed toinvestigate the diagnostic potential 3D-APT, alone conjunction with diffusion-weighted (DWI), distinguishing from non-TNBC. Approach: Quantitative analysis comparison...