A5100404786- Acute Ischemic Stroke Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
- Neurological Disease Mechanisms and Treatments
- Neurological Disorders and Treatments
- Venous Thromboembolism Diagnosis and Management
- Neurosurgical Procedures and Complications
- Retinal Imaging and Analysis
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebral Venous Sinus Thrombosis
- Glaucoma and retinal disorders
- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and genetic disorders
- Cardiovascular Health and Disease Prevention
- Retinal Diseases and Treatments
- Neurological and metabolic disorders
- Advanced Glycation End Products research
- Retinal and Optic Conditions
- Dementia and Cognitive Impairment Research
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Autoimmune Bullous Skin Diseases
- Atrial Fibrillation Management and Outcomes
- Asthma and respiratory diseases
- Blood Pressure and Hypertension Studies
Sichuan University
2016-2025
West China Hospital of Sichuan University
2016-2025
Chongqing Municipal Government
2025
Xi'an Jiaotong University
2024-2025
Xi'an Honghui Hospital
2024-2025
Inner Mongolia Agricultural University
2025
Changzhou University
2025
China Medical University
2009-2024
The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture
2017-2024
Beijing Proteome Research Center
2024
Early control of elevated blood pressure is the most promising treatment for acute intracerebral haemorrhage. We aimed to establish whether implementing a goal-directed care bundle incorporating protocols early intensive lowering and management algorithms hyperglycaemia, pyrexia, abnormal anticoagulation, implemented in hospital setting, could improve outcomes patients with spontaneous
Acupuncture is a frequently used complementary treatment for ischemic stroke in China but the evidence available from previous randomized trials inconclusive. The objective of this study was to assess efficacy and safety acupuncture more robustly designed larger scale trial. This multicenter, single-blinded, controlled Eight hundred sixty-two hospitalized patients with limb paralysis between 3 10 days after onset were allocated plus standard care or alone. applied 5 times per week 4 weeks....
<h3>Objective:</h3> To examine the potential efficacy of statin treatment in reducing risk poststroke seizures. <h3>Methods:</h3> In this cohort study, patients with a first-ever ischemic stroke and no history epilepsy before were enrolled. After mean follow-up period 2.5 years, assessment was performed to identify epilepsy. Logistic regression Cox analyses used assess relationship between use early-onset seizures or <h3>Results:</h3> Of 1,832 enrolled patients, 63 (3.4%) had 91 (5.0%)...
The present study investigated the antioxidant and neuroprotective effect of kaempferol against rotenone-induced Parkinson’s disease (PD). Kaempferol inhibits apomorphine-induced rotational behavior inhibited lipid peroxidation interleukin (IL)-6 tumor necrosis factor (TNF)-α, while markers were increased in a PD rat model SH-S5Y5 cells. levels monoamine striatum substantia nigra region brain. Histopathological analyses showed that apoptosis. Intracellular reactive oxygen species (ROS)...
Background: Early neurological deterioration (END) is not a rare phenomenon in single subcortical infarction (SSI; traditionally known as lacunar infarction) patients. Predictors of END SSI patients are uncertain. Aims: We aimed to investigate the association between infarct lesion characteristics, penetrating artery morphology, carrier plaque features and using whole-brain vessel-wall imaging. Methods: prospectively collected data from without stenosis corresponding artery. The size...
We aimed to develop and validate a prognostic model for predicting malignant brain oedema in patients with acute ischaemic stroke real-world setting of practice.A prospective multicentre study enrolled adult CT < 24 h onset symptoms admitted nine tertiary-level hospitals China between September 2017 December 2019. Malignant was defined as any patient who had decompressive craniectomy, discharge coma, or in-hospital death attributed symptomatic swelling. The derivation cohort consecutive from...
Background: High-resolution magnetic resonance vessel wall imaging (HRMR-VWI) is a promising technique for identifying intracranial vulnerable plaques beyond lumen narrowing. However, the association between HRMR-VWI characteristics and recurrent stroke remains uncertain. Aims: This study aimed to investigate ipsilateral in patients with symptomatic atherosclerotic steno-occlusive disease (ICAS). Methods: multicenter, observational recruited first-ever acute ischemic attributed ICAS (>50%...
This study addresses the urgent need for non-invasive early-onset Alzheimer's disease (EOAD) prediction. Using optical coherence tomography angiography (OCTA), we present a choriocapillaris model sensitive to EOAD, correlating with serum biomarkers.
Abstract To investigate the effects of low frequency electromagnetic fields (EMF) on proliferation epidermal stem cells, human cells (hESC) were isolated, expanded ex vivo, and then exposed to a EMF. The test control placed under same environment. for 30 min/day 5 mT EMF at 1, 10, 50 Hz 3, 5, or 7 days. cell proliferation, cycle, cell‐surface antigen phenotype investigated. Low significantly enhanced hESC in culture medium frequency‐dependent manner, with highest rate ( P < 0.05)....
Abstract Backgrounds Surgical resection and adjunct chemotherapy or radio-therapy has been applied for the therapy of superficial malignant tumor in clinics. Whereas, there are still some problems limit its clinical use, such as severe pains side effect. Thus, it is urgent need to develop effective, minimally invasive low toxicity stagey tumor. Topical drug administration microneedle patches shows advantages reduced systemic nimble application and, a result, great potential treat tumors....
We aimed to use novel whole-brain vessel-wall magnetic resonance imaging (WB-VWI) investigate the association between plaque distribution of middle cerebral artery (MCA) and morphological changes lenticulostriate arteries (LSAs) in single subcortical infarctions.Forty infarction patients with no relevant MCA disease on angiography were prospectively enrolled. Plaque location was dichotomized as proximal (located adjacent LSA origin) or distal imaging. The MCAs plaques divided into...