A5027747170- Advanced Glycation End Products research
- Greenhouse Technology and Climate Control
- Plant tissue culture and regeneration
- Ginseng Biological Effects and Applications
- Nematode management and characterization studies
- Plant Genetic and Mutation Studies
- Plant Water Relations and Carbon Dynamics
- Phytochemicals and Antioxidant Activities
- Complement system in diseases
- Metallurgy and Material Forming
- Studies on Chitinases and Chitosanases
- Biochemical effects in animals
- Pharmacological Effects of Natural Compounds
- Tea Polyphenols and Effects
- Metal Forming Simulation Techniques
- Protein Hydrolysis and Bioactive Peptides
- Irrigation Practices and Water Management
- Plant Toxicity and Pharmacological Properties
- Moringa oleifera research and applications
- Bioenergy crop production and management
- Medicinal Plants and Neuroprotection
- Mollusks and Parasites Studies
- Phytochemicals and Medicinal Plants
- Hippo pathway signaling and YAP/TAZ
- Seed and Plant Biochemistry
Central China Normal University
2025
Wageningen University & Research
2022-2025
University of Kansas Medical Center
2022-2025
Institut de Biologie systémique et synthétique
2024
China Agricultural University
2016-2023
Ministry of Agriculture and Rural Affairs
2023
Jianghan University
2022
Second Hospital of Anhui Medical University
2022
Anhui Medical University
2022
Shanghai Jiao Tong University
2017-2021
In the study of solar greenhouses, microclimate, soil, and back walls have an important influence on greenhouse thermal environment because their good heat storage release characteristics. The transpiration crops makes indoor humidity increase sharply, which is main factor affecting distribution. Therefore, it great significance to grasp microclimate change law greenhouses coupling effect environment. this paper, based computational fluid dynamics (CFD), a three-dimensional model...
α-Dicarbonyl compounds, particularly methylglyoxal (MGO), glyoxal (GO), and 3-deoxyglucosone (3-DG), are highly reactive precursors for the formation of advanced glycation end products (AGEs). They formed in vivo during food processing. This study aimed to investigate role intracellular glutathione (GSH) levels induction Nrf2-mediated gene expression by α-dicarbonyl compounds. The reactions between compounds (MGO, GO, 3-DG) GSH were studied LC-MS a cell-free system. It was shown that these...
Over 1,000 pyrrolizidine alkaloids (PAs) and their N-oxides (PA-N-oxides) occur in 3% of all flowering plants. PA-N-oxides are toxic when reduced to parent PAs, which bioactivated into pyrrole intermediates that generate protein- DNA-adducts resulting liver toxicity carcinogenicity. Literature data for senecionine N-oxide rats indicate the relative potency (REP) value this PA-N-oxide compared its PA varies with endpoint used. The first was ratio between area under concentration-time curve...
Methylglyoxal (MGO), a highly reactive precursor of advanced glycation end products, is endogenously produced and prevalent in various food products. This study aimed to characterize protein modifications SH-SY5Y human neuroblastoma cells induced by MGO identify potential biomarkers for its exposure toxicity. A shot-gun proteomic analysis was applied treated with without exogenous MGO. Seventy-seven proteins were identified as susceptible modification, among which eight, including vimentin...
This study aimed to highlight the molecular and biochemical changes induced by methylglyoxal (MGO) exposure in SH-SY5Y human neuroblastoma cells, explore how these contribute its neurotoxicity, utilizing an integrated proteomics metabolomics approach. Using label-free quantitative nanoLC-MS/MS targeted LC-TQ-MS/MS-based metabolomics, results revealed that MGO exposure, particularly at cytotoxic levels, significantly altered proteome metabolome of cells. Analysis data showed significant...
In this study, four polysaccharide fractions designated as RGP1, RGP2, RGP3, and RGP4 were isolated from red ginseng by DEAE-52 cellulose chromatography, their macrophage immunomodulatory activities investigated. The results revealed that the proliferation, NO production, neutral phagocytosis of RAW 264.7 cells in groups treated with RGP1 RGP2 vitro increased significantly compared to RGP3 RGP4. addition, level TNF- α was groups. All consistently indicated had strong activities. Furthermore,...
Abstract A rapid, simple, and efficient liquid-phase microextraction (LPME) method coupled with high-performance liquid chromatography ultraviolet detection for the analysis of triazine herbicides was developed in this study. Under optimum conditions, enrichment factors extraction recoveries were 33.0–72.6 11.2–23.2%, respectively. The limits (LODs) range 0.03–0.10 µg L−1. relative standard deviations determination at μg L−1 levels varied 2.05–8.15%. successfully applied aqueous samples...
This study aimed to characterize the methylglyoxal (MGO) scavenging capacity of glutathione (GSH) and kaempferol in more detail with special emphasis on possible reversible nature adduct formation their competition for MGO, safety consequences MGO-scavenging effects. GSH showed immediate concentration-dependent effects, while effects by appeared concentration- but also time-dependent, stable adducts formed over time. The gradually disappeared a reaction kaempferol, became preferred scavenger...
Seed dormancy, a main factor contributing to preharvest sprouting (PHS) tolerance, is an adaptive trait largely affected by environmental conditions, such as temperature and moisture, during seed development after ripening. PHS reduces the end-use of wheat declining grain quality, which leads further economic losses. The cultivar ‘Chinese Spring’ (CS) has ph and kr genes, was always used bridge parent cross with related species in order transfer good genes...
SimiaoYong'an decoction, a traditional Chinese medicine formula consisting of four herbs, has been widely used for the treatment gangrene disease. However, its clinical application is restricted due to lack an effective quality control method that covers main active compounds in formula. In this study, high-performance liquid chromatography with diode-array detection (HPLC–DAD) was established simultaneous determination 13 including harpagide, neochlorogenic acid, chlorogenic...